Results 221 to 230 of about 16,445 (315)

Organoids in Cancer Research and Regenerative Medicine: Current Status, Challenges, and Future Prospects

MedComm, Volume 7, Issue 1, January 2026.
The management of cancer and tissue regeneration remains a substantial challenge to global health. Organoids, which are stem cell‐derived three‐dimensional multicellular structures, are revolutionizing biomedical research. Therefore, this review highlights their applications in cancer research and regenerative medicine, while discussing current ...
Ruiyang Li, Yuezhou Wu, Zhu'anzhen Zheng, Fengjin Zhou, Ke Xu, Jiacan Su   +5 more
wiley   +1 more source

The Global Burden of Cholesteatoma: A Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, Volume 174, Issue 1, Page 45-56, January 2026.
Abstract Objective This systematic review and meta‐analysis sought to estimate the global and World Health Organization (WHO) regional prevalence and burden of cholesteatoma. Data Sources PubMed, APA PsycINFO, the Cochrane Library, Embase, and WHO International Clinical Trials Registry Platform (ICTRP) from 2010 to 2025.
Herbert Melariri, Yusentha Balakrishna, Abdiwahab Mukhtar, Elizabeth Joseph, Simone Labuschagne, Racheal Hapunda‐Chibanga, Sara Finestone, Allison Bosman, Onyinyechi Ukaegbe, Haben Birhane Werkineh, Marc Merven, Amina Seguya, Blessing Melariri, Lillian Mokoh, Timothy Els, Daniel Tharratt, Amir Murtaza, Mohamed Moosajee, Tashneem Harris, Lucky Onotai, Ida Amir, Paula Melariri   +21 more
wiley   +1 more source

Ancestral Origin and Structural Characteristics of Non‐Syntenic Homologous Chromosomes in Abalones (Haliotis)

Molecular Ecology Resources, Volume 26, Issue 1, January 2026.
ABSTRACT Structural variation is increasingly recognised as a pivotal contributor to genomic diversity in marine invertebrates, yet its extent and evolutionary significance remain poorly characterised in many species. Haplotype‐phased genome assembly is an excellent resource for studying such variations by comparing homologous chromosomes.
Shotaro Hirase, Takashi Makino, Takeshi Takeuchi, Mitsutaka Kadota, Shigehiro Kuraku, Kiyoshi Kikuchi   +5 more
wiley   +1 more source

Primary Antibody Deficiency in Patients With Chronic Rhinosinusitis: A Call for Immunologic Evaluation Prior to Biologic Therapy

Clinical Otolaryngology, Volume 51, Issue 1, Page 144-152, January 2026.
ABSTRACT Objective Chronic rhinosinusitis (CRS) is prevalent and causes a great negative impact on quality of life. Primary antibody deficiency (PAD) is highly prevalent with CRS compared to the background population. There are efficient treatment options to consider when CRS is a symptom of PAD. The condition seems to be underdiagnosed.
Anita García Petersen, Kasra Zainali‐Gill, Carsten Schade Larsen, Christian Nielsen, Therese Ovesen   +4 more
wiley   +1 more source

Tryptophan Suppresses FTH1‐Driven Ferritinophagy, a Key Correlate of Prognosis in Hepatocellular Carcinoma

Cell Proliferation, Volume 59, Issue 1, January 2026.
Intracellular tryptophan levels modulate selective autophagy of FTH1 via the NCOA4 pathway. This autophagic process then inhibits 6‐HMT synthesis, which then results in an increase in reactive oxygen species and ferroptosis. ABSTRACT Hepatocellular carcinoma (HCC) remains a lethal malignancy with limited therapeutic options.
Xinxiang Cheng, Xin Ge, Chi Zhang, Xingye Yang, Zhengxin Yu, Min Zhang, Wen Cao, Qingtao Ni, Yang Liu, Songbing He, Yin Yuan   +10 more
wiley   +1 more source

Health-related quality of life among a group of Egyptian children with inborn errors of immunity: a cross-sectional study [PDF]

Yehia El-gamal, Azza M. Youssef, A. M. El sayed, Nesrine Radwan   +3 more
openalex   +1 more source

Rheumatologic manifestations in children with underlying inborn errors of immunity. [PDF]

BMC Rheumatol
Saeidi Z, Fadai S, Mesdaghi M, Mirzaee AZ, Sharafian S, Rahmani K, Eslami N, Parvaneh VJ, Talebi M, Chavoshzadeh Z, Shiari R.   +10 more
europepmc   +1 more source

Pharmacotherapy Risks in Rare Genetic Diseases: Cross‐Referencing ACMG Secondary Findings v3.2 List With Clinical Databases

Clinical and Translational Science, Volume 19, Issue 1, January 2026.
ABSTRACT Clinical genomics and pharmacogenomics have largely remained separate fields, though some genetic variants have overlapping disease risk and drug implications. However, the extent of this overlap is not well studied. To explore this gap, we cross‐referenced genes from the American College of Medical Genetics Secondary Findings v3.2 list with ...
Josiah D. Allen, Benjamin Q. Duong, Jordan Brady, Pamela Arn   +3 more
wiley   +1 more source

Liver transplantation: a 31-year perspective. Part I. [PDF]

, 1990
Adler, Ajlouni, Allain, Alper, Alper, Berman, Bernuau, Bilheimer, Bismuth, Bismuth, Bontempo, Brass, Breining, Brems, Brems, Brettschneider, Buist, Burdelski, Busuttil, Campbell, Carter, Casella, Centers for Disease Control, Christensen, Colledan, Colonna, Colonna, Corman, Cox, Craig, Cuervas-Mons, Daloze, Darby, Demetris, Demetris, Dickson, Dubois, Dummer, Dzik, Emond, Erice, Esquivel, Esquivel, Esquivel, Esquivel, Esquivel, Esquivel, Evans, Fisch, Fortner, Fortner, Friend, Fulginiti, Gallinger, Gartner, Ghent, Ghent, Gibas, Gonwa, Groth, Guiot, Haagsma, Hanto, Harbison, Hobart, Hoeg, Hood, Houssin, Huber, Iwatsuki, Iwatsuki, Iwatsuki, Iwatsuki, Iwatsuki, Iwatsuki, Jacobs, Johnson, Kalayoglu, Kaufman, Koneru, Koneru, Kuo, Kusne, L'age-Stehr, Lauchart, Lavivi, Lefkowitch, Lerut, Lewis, Lynch, Mai, Makowka, Makowka, Malatack, Malatack, Marchioro, Margreiter, Margreiter, Marino, Markus, Markus, Marsh, Merion, Mieles, Miller, Millis, Mora, Mulbacher, Nalesnik, Nalesnik, Neuberger, Neuberger, Neuberger, O'Donnell, O'Grady, O'Grady, O'Grady, O'Grady, O'Grady, Opelz, Ostberg, Osther, Paradis, Parkman, Peleman, Pichlmayr, Pichlmayr, Polson, Polson, Polson, Polson, Popper, Portmann, Prompt, Purtilo, Putnam, Rakela, Rakela, Raum, Ringe, Rizzetto, Rubin, Saliba, Samuel, Samuel, Schmid, Schnitzer, Schroter, Schroter, Seltman, Shaffer, Shaffer, Shaw, Shaw, Sheil, Shiel, Sinclair, Sokol, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Starzl, Stieber, Stock, Stone, Strong, Tarter, Teperman, Teperman, Terpstra, Terpstra, Trey, Trey, Tzakis, Tzakis, Urbach, Van Thiel, Van Thiel, Vogel, Wall, Wall, Wallwork, Watts, Weiss, Williams, Williams, Wolff, Wolpl, Wolpl, Woodle, Yacoub, Zeldis, Ziegler, Zitelli, Zitelli, Zitelli   +212 more
core   +1 more source

Dupilumab for atopic manifestations in pediatric patients with inborn errors of immunity: efficacy and safety in a genetically diverse cohort. [PDF]

Front Immunol
Alsediq N, Algholaiqa T, Alnami G, AlJaber AN.   +3 more
europepmc   +1 more source