Results 91 to 100 of about 1,111,501 (280)

On the prediction of simultaneous inbreeding coefficients at multiple loci

open access: yesGenetical Research, 2004
A new deterministic method for predicting simultaneous inbreeding coefficients at three and four loci is presented. The method involves calculating the conditional probability of IBD (identical by descent) at one locus given IBD at other loci, and multiplying this probability by the prior probability of the latter loci being simultaneously IBD.
Hernandez Sanchez, Julio   +2 more
openaire   +3 more sources

Genotyping Contemporary Captive and Historical Wild Western Lowland Gorillas Indicates Captive Breeding Is Maintaining Genetic Diversity in a Critically Endangered Primate

open access: yesAnimal Conservation, EarlyView.
Captive populations of threatened species risk losing genetic diversity over time. We evaluated the genetic status of contemporary captive western lowland gorillas (Gorilla gorilla gorilla) at Howletts and Port Lympne and compared this with specimens from a historical wild population.
Jaimie Morris   +5 more
wiley   +1 more source

Estimates of inbreeding coefficient from ROH.

open access: yes, 2018
Estimates of inbreeding coefficient from ROH.
Kelly Nunes (255120)   +6 more
core   +1 more source

Genomic Assessment of Reintroduced African Wild Dogs Informs Conservation Translocations

open access: yesAnimal Conservation, EarlyView.
Few reintroduction and translocation programs incorporate genomic assessments into management planning, despite ongoing debate over how founder individuals should be selected. Here, we assess the genomic composition of reintroduced African wild dog (Lycaon pictus) populations in private reserves in South Africa, comparing them with a free‐roaming ...
Michou Weimar   +4 more
wiley   +1 more source

Predicting rates of inbreeding: in populations undergoing selection [PDF]

open access: yes, 2000
Tractable forms of predicting rates of inbreeding (Delta F) in selected populations with general indices, nonrandom mating, and overlapping generations were developed, with the principal results assuming a period of equilibrium in the selection process ...
Woolliams, J.A.   +2 more
core  

Inverse inbreeding coefficient problems with an application to linkage analysis of recessive diseases in inbred populations [PDF]

open access: yes, 2000
Medical geneticists connect relatives having the same disease into a family structure called a pedigree. Genetic linkage analysis uses pedigrees to find the approximate chromosomal locations of disease-causing genes. The problem of choosing a pedigree is
Biesecker, Leslie G.   +5 more
core   +1 more source

Tipping the Scales Using Cryopreservation: Modelling the Genetic Value and Management Potential of Integrated Cryopreservation for Threatened Ex‐Situ Pupfish Populations

open access: yesAnimal Conservation, EarlyView.
This graphical abstract depicts the number of additional fish that would be required to achieve 90% genetic diversity for endangered pupfish species housed in EAZA collections, with or without the use of cryopreserved material. ABSTRACT Zoos and aquaria must retain genetic diversity for the species they house if the populations are to remain viable ...
James Edward Brereton   +5 more
wiley   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

open access: yesAndrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou   +8 more
wiley   +1 more source

Summary of inbreeding coefficient estimates across cohorts, and association testing.

open access: yes, 2013
For each case and control group we present the average the estimated inbreeding coefficient and the number of individuals with inbreeding coefficients above a specified threshold.
Ni Huang (19501)   +29 more
core   +1 more source

Genomics‐informed management of ex situ populations

open access: yesConservation Biology, EarlyView.
Abstract The European Association of Zoos and Aquariums (EAZA) manages insurance populations for hundreds of species through its EAZA ex situ programs (EEPs). EEPs help safeguard against extinction in the wild and provide source populations for genetic rescue programs.
Cock van Oosterhout   +8 more
wiley   +1 more source

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