Results 11 to 20 of about 243,471 (265)

Ocimum sanctum linn: An ethnomedicinal herb as a potential source of anti-carcinogen against various cancer diseases and effective ways to include the basil in everyday diet

International journal of health sciences, 2022
Ethno-medicines have been playing a vital role throughout human history in the day to day healthcare routine. Before the evolution of western medicine, for thousands of years, people have been using traditional medicine for the treatment of different diseases.
C. Joy Hepzibah, V. David Arputha Raj
openaire   +1 more source

Investigating the different mechanisms of genotoxic and non-genotoxic carcinogens by a gene set analysis. [PDF]

PLoS ONE, 2014
Based on the process of carcinogenesis, carcinogens are classified as either genotoxic or non-genotoxic. In contrast to non-genotoxic carcinogens, many genotoxic carcinogens have been reported to cause tumor in carcinogenic bioassays in animals.
Won Jun Lee, Sang Cheol Kim, Seul Ji Lee, Jeongmi Lee, Jeong Hill Park, Kyung-Sang Yu, Johan Lim, Sung Won Kwon   +7 more
doaj   +1 more source

Tobacco smoking as risk factor of laryngeal cancer

Journal of Education, Health and Sport, 2019
Introduction: Laryngeal cancer is one of the most common type of head and neck cancers. It develops due to spontaneous mutation or influence of external factors (physical, biological and chemical).
Michał Konopelko, Olga Padała, Adrianna Krupa, Maciej Putowski, Ewa Piasek   +4 more
doaj   +3 more sources

Data from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage

, 2023
<div>Abstract<p>Cancer prevention is a cost-effective alternative to treatment. In mice, the mTOR inhibitor rapamycin prevents distinct spontaneous, noninflammatory cancers, making it a candidate broad-spectrum cancer prevention agent.
Tyler J. Curiel, Zelton D. Sharp, Paul Hasty, Aijie Liu, Danielle Callaway, Sherry Dodds, Vincent Hurez, Yang Liu, Srilakshmi Pandeswara, Vinh Dao   +9 more
openaire   +1 more source

The research progress in the interaction between Candida albicans and cancers

Frontiers in Microbiology, 2022
Candida albicans is an opportunistic pathogenic fungus, which tends to infect the host with defective immune function including cancer patients. A growing number of studies have shown that C. albicans infection increases the host susceptibility to cancer
Dalang Yu, Zhiping Liu
doaj   +1 more source

Supplemental Figures S1-4 from Prevention of Carcinogen and Inflammation-Induced Dermal Cancer by Oral Rapamycin Includes Reducing Genetic Damage

, 2023
<p>Supplemental Figures S1-4. Supplementary Figure S1: eRapa prevents DMBA/TPA-induced dermal neoplasia and malignant degeneration in WT mice. Supplementary Figure S2: eRapa does not suppress mTORC1 signaling in whole skin. Supplementary Figure S3: eRapa is not a calorie restriction mimetic.
Tyler J. Curiel, Zelton D. Sharp, Paul Hasty, Aijie Liu, Danielle Callaway, Sherry Dodds, Vincent Hurez, Yang Liu, Srilakshmi Pandeswara, Vinh Dao   +9 more
openaire   +1 more source

The mutational signature profile of known and suspected human carcinogens in mice

Nature Genetics, 2020
Epidemiological studies have identified many environmental agents that appear to significantly increase cancer risk in human populations. By analyzing tumor genomes from mice chronically exposed to 1 of 20 known or suspected human carcinogens, we reveal ...
L. Riva, A. Pandiri, Y. R. Li, A. Droop, J. Hewinson, M. Quail, V. Iyer, Rebecca Shepherd, R. Herbert, P. Campbell, R. Sills, L. Alexandrov, A. Balmain, D. Adams   +13 more
semanticscholar   +1 more source

Unboxing the molecular modalities of mutagens in cancer

Environmental science and pollution research international, 2021
The etiology of the majority of human cancers is associated with a myriad of environmental causes, including physical, chemical, and biological factors. DNA damage induced by such mutagens is the initial step in the process of carcinogenesis resulting in
S. Kumari, Sudhanshu Sharma, Dia Advani, A. Khosla, Pravir Kumar, R. K. Ambasta   +5 more
semanticscholar   +1 more source

Application of the key characteristics of carcinogens in cancer hazard identification

Carcinogenesis, 2018
Smith et al. (Env. Health Perspect. 124: 713, 2016) identified 10 key characteristics (KCs), one or more of which are commonly exhibited by established human carcinogens.
K. Guyton, I. Rusyn, W. Chiu, D. Corpet, M. van den Berg, M. Ross, D. Christiani, F. Beland, Martyn T. Smith   +8 more
semanticscholar   +1 more source

Opiate and Tobacco Use and Exposure to Carcinogens and Toxicants in the Golestan Cohort Study

Cancer Epidemiology, Biomarkers and Prevention, 2020
Background: There is little information on human exposure to carcinogens and other toxicants related to opiate use, alone or in combination with tobacco. Methods: Among male participants of the Golestan Cohort Study in Northeast Iran, we studied 28 never
A. Etemadi, H. Poustchi, A. Calafat, B. Blount, V. D. De Jesús, Lanqing Wang, A. Pourshams, Ramin Shakeri, Maki Inoue-Choi, M. Shiels, G. Roshandel, G. Murphy, C. Sosnoff, Deepak Bhandari, June Feng, B. Xia, Yuesong Wang, Lei Meng, F. Kamangar, P. Brennan, P. Boffetta, S. Dawsey, C. Abnet, R. Malekzadeh, N. Freedman   +24 more
semanticscholar   +1 more source