Results 31 to 40 of about 260,941 (267)

Dietary Compounds as Epigenetic Modulating Agents in Cancer

open access: yesFrontiers in Genetics, 2019
Epigenetic mechanisms control gene expression during normal development and their aberrant regulation may lead to human diseases including cancer. Natural phytochemicals can largely modulate mammalian epigenome through regulation of mechanisms and ...
Ángeles Carlos-Reyes   +8 more
semanticscholar   +1 more source

Endocrine disruptors from the environment affecting breast cancer

open access: yesOncology Letters, 2020
Evaluation of carcinogenic substances from the environment is a challenge for scientists. Recently, a novel approach based on 10 key characteristics of human carcinogens classified by the International Agency for Research on Cancer (IARC) has emerged ...
G. Calaf   +4 more
semanticscholar   +1 more source

Squamous Cancer of the Esophagus in Africa: A Causal Pathway Established

open access: yesAsian Pacific Journal of Cancer Biology, 2022
Squamous cancer of the esophagus has been endemic in much of East, Central and Southern Africa since the 1940s. Much research has concentrated on attempts to identify major carcinogenic influences, and failure to do so has made it clear that the problem ...
Alastair M Sammon
doaj   +1 more source

DNA Methylation as a Molecular Mechanism of Carcinogenesis in World Trade Center Dust Exposure: Insights from a Structured Literature Review

open access: yesBiomolecules
The collapse of the World Trade Center (WTC) buildings in New York City generated a large plume of dust and smoke. WTC dust contained human carcinogens including metals, asbestos, polycyclic aromatic hydrocarbons (PAHs), persistent organic pollutants ...
Stephanie Tuminello   +7 more
doaj   +1 more source

Environmental risk factors for cancer - review paper.

open access: yesAnnals of Agricultural and Environmental Medicine, 2019
The cancerous process is result of disturbed cell function. This is due to the accumulation of many genetic and epigenetic changes within the cell, expressed in the accumulation of chromosomal or molecular aberrations, which leads to genetic instability.
A. Lewandowska   +4 more
semanticscholar   +1 more source

Establishing a Policy Framework for the Primary Prevention of Occupational Cancer: A Proposal Based on a Prospective Health Policy Analysis

open access: yesSafety and Health at Work, 2017
Background: Despite our knowledge of the causes of cancer, millions of workers are involuntarily exposed to a wide range of known and suspected carcinogens in the workplace. To address this issue from a policy perspective, we developed a policy framework
Amanda Veglia   +2 more
doaj   +1 more source

Synthetic Receptors for Early Detection and Treatment of Cancer

open access: yesBiosensors, 2023
Over recent decades, synthetic macrocyclic compounds have attracted interest from the scientific community due to their ability to selectively and reversibly form complexes with a huge variety of guest moieties. These molecules have been studied within a
Frank Davis, Séamus P. J. Higson
doaj   +1 more source

An Assessment on Ethanol-Blended Gasoline/Diesel Fuels on Cancer Risk and Mortality

open access: yesInternational Journal of Environmental Research and Public Health, 2021
Although cancer is traditionally considered a genetic disease, the epigenetic abnormalities, including DNA hypermethylation, histone deacetylation, and/or microRNA dysregulation, have been demonstrated as a hallmark of cancer.
Steffen Mueller   +2 more
semanticscholar   +1 more source

Hallmarks of Cancer-Related Newly Prognostic Factors of Oral Squamous Cell Carcinoma

open access: yesInternational Journal of Molecular Sciences, 2018
Head and neck cancer, including oral squamous cell carcinoma (OSCC), is the sixth leading malignancy worldwide. OSCC is an aggressive tumor and its prognosis has exhibited little improvement in the last three decades.
T. Sasahira, T. Kirita
semanticscholar   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

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