Mutations in pathways depending on BRCA1 and BRCA2 may increase cancer risks from an environmental carcinogen [PDF]
, 2011 Recently, the President’s Cancer Panel [2008-2009] protested that preventive action is not taken when uncertainty exists about potential harm from a chemical, because the US regulatory approach demands that a hazard be incontrovertibly ...
Bernard Friedenson
core +2 more sources
West Kazakhstan Medical JournalThis paper examines the impact of global warming on cancer development, specifically focusing on the intensified effects of environmental carcinogens such as ultraviolet (UV) radiation and air pollutants.
Pardis Shirkani, Afshin Shirkani
doaj +1 more source
Frontiers in Public Health, 2018 Cancer is a significant health problem in the Middle East and global population. It is well established that there is a direct link between tobacco smoking and cancer, which will continue to pose a significant threat to human health.
Mohammed A. I. Al-Obaide +3 more
doaj +1 more source
Genomic Changes in Normal Breast Tissue in Women at Normal Risk or at High Risk for Breast Cancer
Breast Cancer: Basic and Clinical Research, 2016 Sporadic breast cancer develops through the accumulation of molecular abnormalities in normal breast tissue, resulting from exposure to estrogens and other carcinogens beginning at adolescence and continuing throughout life.
David N. Danforth
doaj +1 more source
Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development
Frontiers in Immunology, 2021 Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer.
Christoph F. A. Vogel +16 more
doaj +1 more source
Recent perspectives on the relations between faecal mutagenicity, genotoxicity and diet [PDF]
, 2011 Peer reviewedPublisher ...
Hani eEl-Nezami +3 more
core +4 more sources
Occupational cancers – Epidemiology and certification
Medycyna Pracy, 2018 The etiology of cancer is multifactorial. Malignant tumors caused by factors occurring in the work environment, classified as carcinogenic in humans, can be recognized as an occupational disease.
Marta Wiszniewska +6 more
doaj +1 more source
Deep Neural Networks integrating genomics and histopathological images for predicting stages and survival time-to-event in colon cancer [PDF]
arXiv, 2022 There exists unexplained diverse variation within the predefined colon cancer stages using only features either from genomics or histopathological whole slide images as prognostic factors. Unraveling this variation will bring about improved in staging and treatment outcome, hence motivated by the advancement of Deep Neural Network libraries and ...
arxiv
Small Businesses, Public Health, and Scientific Integrity [PDF]
, 2013 This report examines the activities of an independent office within the Small Business Administration: the Office of Advocacy. The Office of Advocacy has responsibility for ensuring that federal agencies evaluate the small business impacts of the rules ...
Katie Greenhaw +2 more
core
An agent-based modelling framework to study growth mechanisms in EGFR-L858R mutant alveolar type II cells [PDF]
arXiv, 2023 Mutations in the epidermal growth factor receptor (EGFR) are common in non-small cell lung cancer (NSCLC), particularly in never-smoker patients. However, these mutations are not always carcinogenic, and have recently been reported in histologically normal lung tissue from patients with and without lung cancer.
arxiv