Results 31 to 40 of about 236,953 (124)

Epigenetic mechanisms in metal carcinogenesis

open access: yesToxicology Reports, 2022
Many metals exhibit genotoxic and/or carcinogenic effects. These toxic metals can be found ubiquitously – in drinking water, food, air, general use products, in everyday and occupational settings.
Luka Manić   +6 more
doaj   +1 more source

Occupational cancers – Epidemiology and certification

open access: yesMedycyna Pracy, 2018
The etiology of cancer is multifactorial. Malignant tumors caused by factors occurring in the work environment, classified as carcinogenic in humans, can be recognized as an occupational disease.
Marta Wiszniewska   +6 more
doaj   +1 more source

Microbiome and cancer

open access: yesLibri Oncologici, 2021
The aim of this review paper is to present the complex interactions between microbiome and the host and the importance of the microbiome in maintaining homeostasis.
Franjo Cmrečak   +3 more
doaj   +1 more source

Targeting the Aryl Hydrocarbon Receptor Signaling Pathway in Breast Cancer Development

open access: yesFrontiers in Immunology, 2021
Activation of the aryl hydrocarbon receptor (AhR) through environmental exposure to known human carcinogens including dioxins can lead to the promotion of breast cancer.
Christoph F. A. Vogel   +16 more
doaj   +1 more source

The effects of cigarette smoking extracts on cell cycle and tumor spread: novel evidence

open access: yesFuture Science OA, 2019
Cigarette smoking is a major preventable risk factor for lung cancer, contributing to lung cancer progression and metastasis. Moreover, cigarette smoking correlates with increased metastasis frequency of pancreatic, breast and bladder cancer.
Aldo Pezzuto   +3 more
doaj   +1 more source

Extremely high Tp53 mutation load in esophageal squamous cell carcinoma in Golestan Province, Iran. [PDF]

open access: yesPLoS ONE, 2011
Golestan Province in northeastern Iran has one of the highest incidences of esophageal squamous cell carcinoma (ESCC) in the world with rates over 50 per 100,000 person-years in both sexes. We have analyzed TP53 mutation patterns in tumors from this high-
Behnoush Abedi-Ardekani   +16 more
doaj   +1 more source

Rare malignancies in Eastern India, socio-economic impact

open access: yesRare Tumors, 2016
The etiology of cancer is multifactorial. Various factors, including physical carcinogens, chemicals and viral carcinogens affect patients with known predisposing factors who subsequently develop malignancies. Here is a retrospective study of 18 patients
Surendra Senapati   +3 more
doaj   +1 more source

Key characteristics of carcinogens meet hallmarks for prevention-cutting the Gordian knot

open access: yesFrontiers in Oncology
The complexity of cancer requires a comprehensive approach to understand its diverse manifestations and underlying mechanisms. Initially outlined by Hanahan and Weinberg in 2000 and updated in 2010, the hallmarks of cancer provide a conceptual basis for ...
Sasi S. Senga   +3 more
doaj   +1 more source

Tobacco, air pollution, environmental carcinogenesis, and thoughts on conquering strategies of lung cancer

open access: yesCancer Biology & Medicine, 2019
Each year there will be an estimated 2.1 million new lung cancer cases and 1.8 million lung cancer deaths worldwide. Tobacco smoke is the No.1 risk factors of lung cancer, accounting for > 85% lung cancer deaths. Air pollution, or haze, comprises ambient
Guangbiao Zhou
doaj   +1 more source

Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility

open access: yesCadernos de Saúde Pública, 2002
Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Hatagima Ana
doaj  

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