Libri Oncologici, 2021 The aim of this review paper is to present the complex interactions between microbiome and the host and the importance of the microbiome in maintaining homeostasis.
Franjo Cmrečak +3 more
doaj +1 more source
Rank the triplets: A ranking-based multiple instance learning framework for detecting HPV infection in head and neck cancers using routine H&E images [PDF]
arXiv, 2022 The aetiology of head and neck squamous cell carcinoma (HNSCC) involves multiple carcinogens such as alcohol, tobacco and infection with human papillomavirus (HPV). As the HPV infection influences the prognosis, treatment and survival of patients with HNSCC, it is important to determine the HPV status of these tumours. In this paper, we propose a novel
arxiv
Retrospective on U.S. Health Risk Assessment: How Others Can Benefit [PDF]
, 1995 Dr. Paustenbach reviews the scientific underpinnings of about twenty years of health risk assessment practice and their implications for environmental policy.
Paustenbach, Dennis J.
core +1 more source
Case-control study of arsenic in drinking water and lung cancer in California and Nevada. [PDF]
, 2013 Millions of people are exposed to arsenic in drinking water, which at high concentrations is known to cause lung cancer in humans. At lower concentrations, the risks are unknown.
Balmes, John R +5 more
core +1 more source
A Tukey type trend test for repeated carcinogenicity bioassays, motivated by multiple glyphosate studies [PDF]
arXiv, 2020 In the last two decades, significant methodological progress to the simultaneous inference of simple and complex randomized designs, particularly proportions as endpoints, occurred. This includes: i) the new Tukey trend test approach, ii) multiple contrast tests for binomial proportions, iii) multiple contrast tests for poly-k estimates, and Add-1 ...
arxiv
Attractor structures of signaling networks: Consequences of different conformational barcode dynamics and their relations to network-based drug design [PDF]
Molecular Informatics (2014) 33: 463-468, 2014 Conformational barcodes tag functional sites of proteins, and are decoded by interacting molecules transmitting the incoming signal. Conformational barcodes are modified by all co-occurring allosteric events induced by post-translational modifications, pathogen, drug binding, etc.
arxiv +1 more source
A versatile trend test for the evaluation of tumor incidences in long-term carcinogenicity bioassays [PDF]
arXiv, 2020 For the evaluation of carcinogenicity bioassays a new trend test is proposed which is based on a maximum of arithmetic, ordinal, and logarithmic regression scores as well as the Williams-type contrasts for either crude proportions or more appropriate poly3-estimates for the tumor-by-time relationships. This test provides an almost appropriate power for
arxiv
On a fundamental problem in the analysis of cancer registry data [PDF]
arXiv, 2023 In epidemiology research with cancer registry data, it is often of primary interest to make inference on cancer death, not overall survival. Since cause of death is not easy to collect or is not necessarily reliable in cancer registries, some special methodologies have been introduced and widely used by using the concepts of the relative survival ratio
arxiv
Rare malignancies in Eastern India, socio-economic impact
Rare Tumors, 2016 The etiology of cancer is multifactorial. Various factors, including physical carcinogens, chemicals and viral carcinogens affect patients with known predisposing factors who subsequently develop malignancies. Here is a retrospective study of 18 patients
Surendra Senapati +3 more
doaj +1 more source
Extremely high Tp53 mutation load in esophageal squamous cell carcinoma in Golestan Province, Iran. [PDF]
PLoS ONE, 2011 Golestan Province in northeastern Iran has one of the highest incidences of esophageal squamous cell carcinoma (ESCC) in the world with rates over 50 per 100,000 person-years in both sexes. We have analyzed TP53 mutation patterns in tumors from this high-
Behnoush Abedi-Ardekani +16 more
doaj +1 more source