Results 41 to 50 of about 236,953 (124)
Is DNA methylation the new guardian of the genome?
Molecular Cytogenetics, 2017 Background It has been known for more than 100 years that aneuploidy is an essence of cancer. The question is what keeps the genome stable, thereby preventing aneuploidy. For the past 25 years, it has been proposed that p53 is the “guardian of the genome.
Robert M. Hoffman
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Genetic polymorphisms and metabolism of endocrine disruptors in cancer susceptibility
Cadernos de Saúde PúblicaEpidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Ana Hatagima
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Quality in SportCancer is a disease of genetic material and develops as a result of the accumulation of gradually occurring genetic damage. The transformation of a normal cell into a cancer cell, known as neoplastic transformation, requires several gene mutations.
Maria Ciechacka
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Journal of Traditional and Complementary Medicine, 2013 Excessive oxidative stress induced by reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive metabolites of carcinogens alters cellular homeostasis, leading to genetic/epigenetic changes, genomic instability, neoplastic ...
Jong Hun Lee +4 more
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Genomic alterations and precise medicine of esophageal squamous cell carcinoma
Journal of Bio-X Research, 2018 . Human cancer is a complex disease caused by the interaction of multiple genes and environmental factors. It is known that environmental factors such as smoking, drinking, and food carcinogens are implicated in the development of certain types of cancer
Qionghua Cui, BS +2 more
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Association Study of Polymorphism in CYP3A5 Gene with Bladder Cancer
Armaghane Danesh Bimonthly Journal, 2015 Aims and objectives: The environmental procarcinogen hypothesis of tumour pathogenesis proposes that many carcinogens require metabolic activation by drug metabolizing enzymes to form the proximate carcinogen.
m bakhtiari tajar +3 more
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Progress on internal exposure to typical environmental persistent organic pollutants and cancer
环境与职业医学Environmental pollution is closely linked to the occurrence and development of cancer. Chemical carcinogens are the most important environmental factors causing cancer in humans. Among them, persistent organic pollutants (POPs) are characterized by their
Xuerui MA +5 more
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Pollution of living environment
Zdravniški Vestnik, 2007 Background: Information on cancer causation has come from investigation of the patterns of cancer in human populations and the induction of tumours in experimental animals following treatment with cancer-causing agents.
Ivan Eržen
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Cadernos de Saúde Pública, 2002 Epidemiological studies have estimated that approximately 80% of all cancers are related to environmental factors. Individual cancer susceptibility can be the result of several host factors, including differences in metabolism, DNA repair, altered ...
Ana Hatagima
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生物医学转化Asbestos is a collective term for six natural mineral fibers that have been widely used commercially. These fibers are classified into two main groups: amphibole asbestos (including crocidolite, tremolite, actinolite, anthophyllite, and amosite) and ...
Huang Qiulin, Lian Fuzhi, Chen Tianhui
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