Toll-like receptor 3 (TLR3) plays a major role in the formation of rabies virus Negri Bodies. [PDF]
PLoS Pathogens, 2009 Human neurons express the innate immune response receptor, Toll-like receptor 3 (TLR3). TLR3 levels are increased in pathological conditions such as brain virus infection.
Pauline Ménager +8 more
doaj +1 more source
Viral Inclusion Bodies in Tracheobronchial Epithelium of Asymptomatic Subjects [PDF]
Chest, 1976 During a survey conducted for the cytodiagnosis of early bronchogenic carcinoma, cytoplasmic viral inclusion bodies were found sporadically in tracheobronchial smears of asymtomatic patients of both sexes (ages ranging from 18 to 80 years) undergoing general endotracheal anesthesia for surgery.
Katz, Judith S. +2 more
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The Infectious Disease Ontology in the Age of COVID-19 [PDF]
, 2021 The Infectious Disease Ontology (IDO) is a suite of interoperable ontology modules that aims to provide coverage of all aspects of the infectious disease domain, including biomedical research, clinical care, and public health.
Babcock, Shane +3 more
core +1 more source
Aquareovirus NS80 recruits viral proteins to its inclusions, and its C-terminal domain is the primary driving force for viral inclusion formation. [PDF]
PLoS ONE, 2013 Cytoplasmic inclusion bodies formed in reovirus-infected cells are the sites of viral replication and assembly. Previous studies have suggested that the NS80 protein of aquareovirus may be involved in the formation of viral inclusion bodies.
Ling Shao +4 more
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The N-Terminal of Aquareovirus NS80 Is Required for Interacting with Viral Proteins and Viral Replication. [PDF]
PLoS ONE, 2016 Reovirus replication and assembly occurs within viral inclusion bodies that formed in specific intracellular compartments of cytoplasm in infected cells.
Jie Zhang +4 more
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Cells, 2020 Ebola virus (EBOV) causes severe outbreaks of viral hemorrhagic fever in humans. While virus-host interactions are promising targets for antivirals, there is only limited knowledge regarding the interactions of EBOV with cellular host factors.
Lisa Wendt +6 more
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Cellular Casein Kinase 2 and Protein Phosphatase 2A Modulate Replication Site Assembly of Bluetongue Virus. [PDF]
, 2016 A number of cytoplasmic replicating viruses produce cytoplasmic inclusion bodies or protein aggregates; however, a hallmark of viruses of the Reoviridae family is that they utilize these sites for purposes of replication and capsid assembly, functioning ...
Mohl, Bjorn-Patrick, Roy, Polly
core +1 more source
Unravelling the structure of viral replication complexes at super-resolution
Frontiers in Plant Science, 2013 During infection, many RNA viruses produce characteristic inclusion bodies that contain both viral and host components. These structures were first described over a century ago and originally termed ‘X bodies’, as their function was not immediately ...
Olga eLinnik +4 more
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Differential Disease Susceptibilities in Experimentally Reptarenavirus-Infected Boa Constrictors and Ball Pythons. [PDF]
, 2017 Inclusion body disease (IBD) is an infectious disease originally described in captive snakes. It has traditionally been diagnosed by the presence of large eosinophilic cytoplasmic inclusions and is associated with neurological, gastrointestinal, and ...
Boback, Scott M +9 more
core +1 more source
Viruses, 2020 Members of the Reoviridae family assemble virus factories within the cytoplasm of infected cells to replicate and assemble virus particles. Bluetongue virus (BTV) forms virus inclusion bodies (VIBs) that are aggregates of viral RNA, certain viral ...
Bjorn-Patrick Mohl +4 more
doaj +1 more source