Results 61 to 70 of about 118,473 (208)

Inclusões intracitoplasmáticas hialinas na medular da adrenal de bovinos

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2011
Cytoplasmic inclusion bodies in adrenal medullary chromaffin cells have been described in various species including humans. These inclusions are believed to be related to certain infectious, toxic and neurodegenerative diseases.
L.P Mesquita, C.C Abreu, F Wouters, M.S Varaschin, P.S Bezerra Jr   +4 more
doaj   +1 more source

Human Cytomegalovirus. Studies on the Mechanism of Viral Gytopathology and Inclusion Body Formation.

Experimental Biology and Medicine, 1967
SummaryWhen cultured human fetal fi-broblasts were infected by human cytomegalo-virus, virus-induced morphologic changes consisting of cytopathology, intracytoplasmic and intranuclear inclusion bodies developed during a 72-hour period. Thus, in this system, virus-induced cell changes followed closely upon viral multiplication.
R M, McAllister, J E, Filbert, C R, Goodheart   +2 more
openaire   +2 more sources

Locus coeruleus to basolateral amygdala noradrenergic projections promote anxiety-like behavior [PDF]

, 2017
Increased tonic activity of locus coeruleus noradrenergic (LC-NE) neurons induces anxiety-like and aversive behavior. While some information is known about the afferent circuitry that endogenously drives this neural activity and behavior, the downstream ...
Bhatti, Dionnet L., Bruchas, Michael R., Lawson, Lamley A., McCall, Jordan G., McElligott, Zoe A., Siuda, Edward R., Stuber, Garret D.   +6 more
core   +3 more sources

Phosphorylation of Bluetongue Virus Nonstructural Protein 2 Is Essential for Formation of Viral Inclusion Bodies [PDF]

Journal of Virology, 2005
ABSTRACT In bluetongue virus (BTV)-infected cells, large cytoplasmic aggregates are formed, termed viral inclusion bodies (VIBs), which are believed to be the sites of viral replication and morphogenesis. The BTV nonstructural protein NS2 is the major component of VIBs. NS2 undergoes intracellular phosphorylation and possesses a strong single-
Jens, Modrof, Kostas, Lymperopoulos, Polly, Roy   +2 more
openaire   +2 more sources

Multi-Faceted Roles of Stress Granules in Viral Infection

Microorganisms
Stress granules (SG), dynamic cytoplasmic condensates formed via liquid-liquid phase separation (LLPS), serve as a critical hub for cellular stress adaptation and antiviral defense.
Ruihan Zhao, Xiangdong Li
doaj   +1 more source

Inclusion body myositis, viral infections, and TDP-43: a narrative review

Clinical and Experimental Medicine
AbstractThe ubiquitous RNA-processing molecule TDP-43 is involved in neuromuscular diseases such as inclusion body myositis, a late-onset acquired inflammatory myopathy. TDP-43 solubility and function are disrupted in certain viral infections. Certain viruses, high viremia, co-infections, reactivation of latent viruses, and post-acute expansion of ...
Vitalie Văcăraş, Romana Vulturar, Adina Chiş, Laura Damian   +3 more
openaire   +2 more sources

Ebola Virus Sequesters IRF3 in Viral Inclusion Bodies to Evade Host Antiviral Immunity

, 2023
Abstract Viral inclusion bodies (IBs) are commonly formed during the replication of Ebola virus (EBOV) in infected cells, but their role in viral immune evasion has rarely been explored. Here, we found that interferon regulatory factor 3 (IRF3), but not TANK-binding kinase 1 (TBK-1) or IκB kinase epsilon (IKKε), was recruited and ...
Lin Zhu, Jing Jin, Tingting Wang, Yong Hu, Hainan Liu, Ting Gao, Qincai Dong, Yanwen Jin, Ping Li, Zijing Liu, Xuan Liu, Cheng Cao   +11 more
openaire   +1 more source

The Potyviridae Cylindrical Inclusion Helicase: A Key Multipartner and Multifunctional Protein

Molecular Plant-Microbe Interactions, 2014
A unique feature shared by all plant viruses of the Potyviridae family is the induction of characteristic pinwheel-shaped inclusion bodies in the cytoplasm of infected cells.
M. Sorel, J. A. Garcia, S. German-Retana
doaj   +1 more source

Vimentin inhibits α-tubulin acetylation via enhancing α-TAT1 degradation to suppress the replication of human parainfluenza virus type 3.

PLoS Pathogens, 2022
We previously found that, among human parainfluenza virus type 3 (HPIV3) proteins, the interaction of nucleoprotein (N) and phosphoprotein (P) provides the minimal requirement for the formation of cytoplasmic inclusion bodies (IBs), which are sites of ...
Pengfei Liu, Shengwei Zhang, Jingyi Ma, Dongning Jin, Yali Qin, Mingzhou Chen   +5 more
doaj   +1 more source

Interaction between Cauliflower Mosaic Virus Inclusion Body Protein and Capsid Protein: Implications for Viral Assembly

Virology, 1996
The cauliflower mosaic virus (CaMV) inclusion body protein (pVI) is able to specifically interact with the viral capsid precursor protein (pIV). By using the yeast two-hybrid system and a blot assay, the pIV region required for the recognition of pVI was mapped to the lysine-rich domain.
Himmelbach, A., Chapdelaine, Y., Hohn, T.   +2 more
openaire   +3 more sources