Results 11 to 20 of about 7,022,792 (370)
Coiled-Coil Based Inclusion Bodies and Their Potential Applications [PDF]
Frontiers in Bioengineering and Biotechnology, 2021 The production of recombinant proteins using microbial cell factories is frequently associated with the formation of inclusion bodies (IBs). These proteinaceous entities can be sometimes a reservoir of stable and active protein, might display good ...
Marcos Gil-Garcia, Salvador Ventura
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Inclusion bodies: Not that bad… [PDF]
Frontiers in Microbiology, 2014 The formation of inclusion bodies constitute a frequent event during the production of heterologous proteins in bacterial hosts. Although the mechanisms leading to their formation are not completely understood, empirical data have been exploited trying ...
Ana eRamon +2 more
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Lewy and his inclusion bodies: Discovery and rejection
Dementia & Neuropsychologia, 2017 Fritz Jacob Heinrich Lewy described the pathology of Paralysis agitans [Parkinson disease] and was the first to identify eosinophilic inclusion bodies in neurons of certain brain nuclei, later known as Lewy bodies, the pathological signature of the Lewy ...
Eliasz Engelhardt +1 more
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At-Line Reversed Phase Liquid Chromatography for In-Process Monitoring of Inclusion Body Solubilization [PDF]
Bioengineering, 2021 Refolding is known as the bottleneck in inclusion body (IB) downstream processing in the pharmaceutical industry: high dilutions leading to large operating volumes, slow refolding kinetics and low refolding yields are only a few of the problems that ...
Julian Ebner +6 more
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Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids [PDF]
eLifeDue to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs).
Xiuling Cao +9 more
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Frontiers in Bioengineering and Biotechnology, 2021 Recombinant proteins are becoming increasingly important for industrial applications, where Escherichia coli is the most widely used bacterial host for their production. However, the formation of inclusion bodies is a frequently encountered challenge for
Arshpreet Bhatwa +5 more
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New Perspectives on the Biogenesis of Viral Inclusion Bodies in Negative-Sense RNA Virus Infections
Cells, 2021 Infections by negative strand RNA viruses (NSVs) induce the formation of viral inclusion bodies (IBs) in the host cell that segregate viral as well as cellular proteins to enable efficient viral replication.
O. Dolnik +2 more
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A compendium of specific histopathological bodies in dermatology
Indian Journal of Dermatology, 2021 The spectrum of histopathological variations of most of the Dermatological conditions is so wide and overlapping that even with our current vast knowledge of this discipline, it seems to be a tough task for clinicians as well as Dermatopathologists to ...
Anup Kumar Tiwary +3 more
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Bioresources and Bioprocessing, 2021 The Global Diabetes Compact was launched by the World Health Organization in April 2021 with one of its important goals to increase the accessibility and affordability of life-saving medicine—insulin.
Y. Siew, Wei Zhang
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