Results 11 to 20 of about 7,614,909 (324)
Maturation and detoxification of synphilin-1 inclusion bodies regulated by sphingolipids [PDF]
Due to proteostasis stress induced by aging or disease, misfolded proteins can form toxic intermediate species of aggregates and eventually mature into less toxic inclusion bodies (IBs).
Xiuling Cao +9 more
doaj +2 more sources
Chemical Assistance in Refolding of Bacterial Inclusion Bodies
Escherichia coli is one of the most widely used hosts for the production of recombinant proteins but insoluble expression of heterologous proteins is a major bottleneck in production of recombinant proteins in E. coli.
Mona Alibolandi, Hasan Mirzahoseini
doaj +2 more sources
Recombinant proteins are becoming increasingly important for industrial applications, where Escherichia coli is the most widely used bacterial host for their production. However, the formation of inclusion bodies is a frequently encountered challenge for
Arshpreet Bhatwa +5 more
semanticscholar +1 more source
The Global Diabetes Compact was launched by the World Health Organization in April 2021 with one of its important goals to increase the accessibility and affordability of life-saving medicine—insulin.
Y. Siew, Wei Zhang
semanticscholar +1 more source
A compendium of specific histopathological bodies in dermatology
The spectrum of histopathological variations of most of the Dermatological conditions is so wide and overlapping that even with our current vast knowledge of this discipline, it seems to be a tough task for clinicians as well as Dermatopathologists to ...
Anup Kumar Tiwary +3 more
doaj +1 more source
Inclusion body myositis (IBM) is an inflammatory myopathy with distinctive clinicopathologic features. The etiology of IBM remains elusive. The immune-mediated basis for this disease has been challenged by evidence implicating a number of divergent etiologic factors.
Rabi, Tawil, Robert C, Griggs
openaire +4 more sources
Inclusion Bodies in Ionic Liquids
The pivotal role of proteins in pharmaceuticals is challenged by stability issues, making the study of inclusion bodies—a source of insoluble protein aggregates—increasingly relevant.
András Szabadi +3 more
doaj +1 more source
The idiopathic inflammatory myopathies (IIMs) are a heterogeneous group of rare disorders that share many similarities. In addition to sporadic inclusion body myositis (IBM), these include dermatomyositis, polymyositis, and autoimmune necrotizing myopathy. IBM is the most common IIM after age 50 years.
Mazen M, Dimachkie, Richard J, Barohn
openaire +5 more sources
Many viruses replicate almost entirely in the cytoplasm of infected cells; however, how these pathogens are able to compartmentalize their life cycle to provide favorable conditions for replication and to avoid the litany of antiviral detection ...
Fatoumatta Jobe +4 more
semanticscholar +1 more source

