Results 71 to 80 of about 7,022,792 (370)

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

From glycogen metabolism to Lafora disease [PDF]

open access: yes, 2016
Glycogen synthesis is normally absent in neurons. However, inclusion bodies resembling abnormal glycogen accumulate in several neurological diseases, particularly in progressive myoclonus epilepsy or Lafora disease.
Guinovart, Joan
core  

Yeast prions form infectious amyloid inclusion bodies in bacteria [PDF]

open access: yes, 2012
Background: Prions were first identified as infectious proteins associated with fatal brain diseases in mammals. However, fungal prions behave as epigenetic regulators that can alter a range of cellular processes.
Espargaró Colomé, Alba   +3 more
core   +3 more sources

Protein misfolding specifies recruitment to cytoplasmic inclusion bodies

open access: yesJournal of Cell Biology, 2016
Inclusion bodies containing aggregated disease-associated proteins and polyubiquitin conjugates are universal hallmarks of neurodegenerative diseases. Here, Bersuker et al.
K. Bersuker, M. Brandeis, R. Kopito
semanticscholar   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

C-Terminal Truncation of α 1,6-Fucosyltransferase from Rhizobium Sp. does not Annul the Transferase Activity of the Enzyme [PDF]

open access: yes, 2002
6 pages.-- PMID: 11814863 [PubMed].Recently we have over-expressed the enzyme a 1,6-fucosyltransferase from Rhizobium sp. in Escherichia coli. In this heterologous system the enzyme was mainly expressed as inclusion bodies and the one that was expressed ...
Bastida, Agatha   +2 more
core   +2 more sources

Recovery of bioactive protein from bacterial inclusion bodies using trifluoroethanol as solubilization agent

open access: yesMicrobial Cell Factories, 2016
BackgroundFormation of inclusion bodies poses a major hurdle in recovery of bioactive recombinant protein from Escherichia coli. Urea and guanidine hydrochloride have routinely been used to solubilize inclusion body proteins, but many times result in ...
V. Upadhyay   +4 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Renal Involvement in Congenital Cytomegalovirus Infection: A Systematic Review

open access: yesMicroorganisms, 2021
Background: Congenital cytomegalovirus (cCMV) infection is the most frequent mother-to-child transmitted infection worldwide and a prevalent cause of neonatal disease and long-term morbidity.
María Ríos-Barnés   +3 more
doaj   +1 more source

Planetesimal Accretion in Binary Systems: Role of the Companion's Orbital Inclination

open access: yes, 2009
Recent observations show that planet can reside in close binary systems with stellar separation of only about 20 AU. However, planet formation in such close binary systems is a challenge to current theory.
Armitage   +23 more
core   +1 more source

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