Results 71 to 80 of about 1,292,732 (363)

ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling

FEBS Letters, EarlyView.
In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li, Gerard van der Zon, Peter ten Dijke, Tong Shen   +3 more
wiley   +1 more source

2024 State of the Art Leadership Awards

Journal of Inclusive Postsecondary Education
The Journal of Inclusive Postsecondary Education would like to recognize the following awardees for their contributions to the field. Each honoree received their award at the 2024 State of the Art Conference in Inclusive Postsecondary Education, held in
Beth Myers, Clare Papay
doaj   +1 more source

Supporting All Educators to Take Part in Teacher Professional Learning for Inclusion

Trends in Higher Education, 2023
In the process of ensuring inclusive education, teachers’ individual roles are shifting towards collaborative practice, involving sharing tasks and expertise among a wide range of educational professionals. Policies for inclusion have resulted in a sense
Annet De Vroey, Amélie Lecheval, Simoni Symeonidou   +2 more
doaj   +1 more source

Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells

FEBS Letters, EarlyView.
In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker, Nimit Mistry, Nicoletta Plotegher, Elizabeth R. Westbrook, Michael D. E. Sewell, John Carroll, Gyorgy Szabadkai, Angus J. Bain, Michael R. Duchen   +8 more
wiley   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

FEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász, Albert Bálint Papp, Lukács Sándor Lesinszki, Attila Mócsai, Tamás Varga, László Nagy, Péter Gogolák   +6 more
wiley   +1 more source

Inclusive education

, 2016
Inclusive education is one of the key ideas and driving forces to emerge in education both nationally and internationally over the past 30 years or so. This chapter explores the idea, and origins, of inclusive education and some of the very different ways the term is used in different contexts.
openaire   +4 more sources

Inclusive Educational Technology

Archives of Business Research, 2016
Educational technology is a collection of research approaches to improve education aiming at effective use of technological tools to facilitate learning processes. There is little literature about inclusive educational technology. In this paper we present first a literature research about inclusive educational technology fostering inclusive education ...
Ileana Hamburg, Sascha Bucksch
openaire   +2 more sources

Inclusive education and democracy [PDF]

, 2019
In this article it is argued that inclusive education can be construed as a response to the crisis of modern democracy and its school project. Such a response consists, in part, in the production of a new school normativity, in the light of the ideals ...
Gaete, Alfredo, Luna, Laura
core   +2 more sources

Functional role and folding properties of the glucan‐binding domain of oral bacterial glucansucrase

FEBS Letters, EarlyView.
The role of the glucan‐binding domain in Streptococcus sobrinus glucansucrase was examined, focusing on its impact on enzymatic activity, dextran binding, and structural stability of deletion mutants and a circularly permuted protein. Our research revealed that glucosyl transfer efficiency is linked to cooperative interdomain folding.
Hideyuki Komatsu, Takayuki Sadakane, Yudai Murata, Junichi Taira, Hiroshi Sakamoto, Takao Kodama   +5 more
wiley   +1 more source

Executive Function in Adolescence: Associations with Child and Family Risk Factors and Self-Regulation in Early Childhood

Frontiers in Psychology, 2017
Executive functions are important higher-order cognitive skills for goal-directed thought and action. These capacities contribute to successful school achievement and lifelong wellbeing.
Donna Berthelsen, Nicole Hayes, Nicole Hayes, Sonia L. J. White, Kate E. Williams   +4 more
doaj   +1 more source