Results 231 to 240 of about 21,074 (263)
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2010
WNT signaling is emerging as a global regulator of metabolism, targeting multiple tissues. This is achieved either directly through Wnt receptors, or indirectly through the action of incretins, hormones that enhance glucose-stimulated insulin secretion and target extrapancreatic organs that cooperatively control whole body energy balance. WNT increases
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WNT signaling is emerging as a global regulator of metabolism, targeting multiple tissues. This is achieved either directly through Wnt receptors, or indirectly through the action of incretins, hormones that enhance glucose-stimulated insulin secretion and target extrapancreatic organs that cooperatively control whole body energy balance. WNT increases
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1988
Publisher Summary This chapter provides an overview of incretin. According to LaBarre, incretin refers to endocrine factors from the gut with insulinotropic activity. An incretin should fulfill these conditions: (1) it must be released by nutrients, especially carbohydrates, (2) it must stimulate insulin secretion in the presence of elevated blood ...
W. Creutzfeldt, R. Ebert
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Publisher Summary This chapter provides an overview of incretin. According to LaBarre, incretin refers to endocrine factors from the gut with insulinotropic activity. An incretin should fulfill these conditions: (1) it must be released by nutrients, especially carbohydrates, (2) it must stimulate insulin secretion in the presence of elevated blood ...
W. Creutzfeldt, R. Ebert
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[The concept of incretins and the physiological roles of incretins].
Nihon rinsho. Japanese journal of clinical medicine, 2011Incretins, exemplified by glucagon-like peptide 1(GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) are secreted in a nutrient-dependent manner and stimulate glucose-dependent insulin secretion. Both GLP-1 and GIP also promote beta cell proliferation and inhibit apoptosis, leading to expansion of beta cell mass. GLP-1, but not GIP, controls
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Journal of Medicine and Pharmacy, 2011
The incretins are peptide hormones secreted from the gut in response to food. They increase the secretion of insulin. The incretin response is reduced in patients with type 2 diabetes so drugs acting on incretins may improve glycaemic control. Incretins are metabolised by dipeptidyl peptidase, so selectively inhibiting this enzyme increases the ...
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The incretins are peptide hormones secreted from the gut in response to food. They increase the secretion of insulin. The incretin response is reduced in patients with type 2 diabetes so drugs acting on incretins may improve glycaemic control. Incretins are metabolised by dipeptidyl peptidase, so selectively inhibiting this enzyme increases the ...
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The expanding incretin universe: from basic biology to clinical translation
Diabetologia, 2023Daniel Drucker +2 more
exaly
Incretin hormones: Their role in health and disease
Diabetes, Obesity and Metabolism, 2018Michael Albrecht Nauck, Juris Meier
exaly
Clinical calcium, 2009
Gastrointestinal hormones including gastric inhibitory polypeptide (GIP) and glucagon-like peptide (GLP) -1 are incretin, which are secreted immediately after meal ingestion and stimulate insulin secretion from pancreatic beta-cells. Characterization of extra-pancreatic GIP and GLP-1 receptors has revealed that these hormones regulate bone turnover ...
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Gastrointestinal hormones including gastric inhibitory polypeptide (GIP) and glucagon-like peptide (GLP) -1 are incretin, which are secreted immediately after meal ingestion and stimulate insulin secretion from pancreatic beta-cells. Characterization of extra-pancreatic GIP and GLP-1 receptors has revealed that these hormones regulate bone turnover ...
openaire +1 more source