Results 201 to 210 of about 8,133 (247)

Sexual Safety Signals of Common Antidiabetic Drugs: Insights From FAERS Disproportionality Analysis

Andrology, Volume 14, Issue 6, Page 1627-1635, September 2026.
ABSTRACT Background Erectile dysfunction is a prevalent and distressing complication of diabetes mellitus that markedly affects quality of life in male patients. Although the role of diabetes in erectile dysfunction is well‐established, potential drug‐induced sexual dysfunction associated with commonly prescribed antidiabetic medications remains ...
Shan Lin, Xuefeng Ding, Xin Dang, Qingyuan Zhan   +3 more
wiley   +1 more source

Gαs defines the fundamental coupling mechanism of insulin secretion. [PDF]

J Diabetes Investig
Shirakawa J.
europepmc   +1 more source

MicroRNA‐Driven Regulation of β‐Cell Function in Type 2 Diabetes: Molecular Mechanisms, Network Insights, and Translational Perspectives

Acta Physiologica, Volume 242, Issue 9, September 2026.
ABSTRACT MicroRNAs (miRNAs) have emerged as central regulators of pancreatic islet biology, influencing β‐cell development, proliferation, and function. In type 2 diabetes (T2D), both adaptive and maladaptive miRNA responses shape β‐cell compensation and progressive secretory dysfunction.
Lena Eliasson, Alexandros Karagiannopoulos, Mototsugu Nagao, Anna Wendt   +3 more
wiley   +1 more source

Obstructive Sleep Apnea: An Evolving Therapeutic Landscape with an Emerging Role for Incretin-Based Therapies. [PDF]

Adv Ther
Xu B, Gaynor-Sodeifi K, Kundel V.
europepmc   +1 more source

Dual Glucagon and GLP‐1 Receptor Agonist Survodutide Improves Biomarkers of Beta‐Cell Function and Insulin Sensitivity in People With Type 2 Diabetes or Living With Overweight/Obesity

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8242-8253, September 2026.
ABSTRACT Aims This post hoc analysis evaluated the effect of survodutide on beta‐cell function, insulin sensitivity, and glucose biomarkers in two phase 2 trial populations. Materials and Methods Trial 1404‐0002 randomised 413 participants with type 2 diabetes on metformin to receive survodutide, placebo, or semaglutide over 16 weeks.
Elif I. Ekinci, Sandra González Maldonado, Anna Unseld, Jorge Arrubla Martinez, Anita M. Hennige, Corinna Schoelch   +5 more
wiley   +1 more source

c-Jun N-terminal kinase 3 as a permissive regulator of β-cell incretin responsiveness. [PDF]

J Diabetes Investig
Yamazaki Y.
europepmc   +1 more source

Glucagon‐Like Peptide‐1 Receptor Agonists and Risk of Mental Health Disorders in Type 2 Diabetes: Active Comparator, New User Cohort Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8482-8493, September 2026.
ABSTRACT Aims We evaluated the risk of mental health disorders among glucagon‐like peptide‐1 receptor agonist (GLP1RA) users compared with users of dipeptidyl peptidase‐4 (DPP‐4) inhibitors and sodium‐glucose cotransporter‐2 (SGLT2) inhibitors. Materials and Methods We conducted a nationwide, active‐comparator new‐user cohort study using the Korean ...
Chungsoo Kim, Seonji Kim, Dong Yun Lee, Eugene Han, Yong‐ho Lee, Seng Chan You   +5 more
wiley   +1 more source

Impact of Prolonged Fasting and Refeeding on Enteroendocrine Hormone Expression: One More Piece of the Fasting/Refeeding Metabolic Puzzle. [PDF]

Biomedicines
Nunes G, Guimarães M, Oliveira SB, Pereira SS, Vara-Luiz F, Mendes I, Palma C, Oliveira C, Fonseca J.   +8 more
europepmc   +1 more source

Dose–Response Association Between Systemic and Dermatologic Glucocorticoid Use and Type 2 Diabetes Mellitus: A Nationwide Case–Control Study

Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8094-8102, September 2026.
ABSTRACT Aims To investigate the association and dose–response between systemic and topical glucocorticoids and odds of Type 2 diabetes mellitus. Materials and Methods We conducted a nationwide case–control study using Danish registry data from 2013 to 2021. People aged 40 years or older with incident type 2 diabetes mellitus (n = 149 113) were matched
David Vadsholt, Annika V. Kvist, Chano Sandiramoorthy, Joshua R. Lewis, Peter Vestergaard, Johan Røikjer, Nicklas H. Rasmussen   +6 more
wiley   +1 more source

Incretin polyagonists as an alternative to bariatric surgery to manage obesity. [PDF]

World J Gastrointest Pathophysiol
Manoj RJ, Fernandez CJ, Nair S, Pappachan JM.   +3 more
europepmc   +1 more source