ABSTRACT Aims To evaluate the cardiovascular efficacy and absolute benefit of glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) by baseline estimated glomerular filtration rate (eGFR). Materials and Methods PubMed and EMBASE were searched to 29 April 2026 for randomized placebo‐controlled trials of GLP‐1RAs in adults with type 2 diabetes or ...
Masashi Hasebe +3 more
wiley +1 more source
Regulation of glucose metabolism by incretins: implications for treatment of type 2 diabetes. [PDF]
Saito R, Harada N.
europepmc +1 more source
ABSTRACT Background The obesity pharmacotherapy landscape is evolving rapidly, with several approved incretin‐based therapies and an expanding pipeline of investigational compounds targeting multiple metabolic pathways. Conventional evidence syntheses often struggle to accommodate differences in dose selection, treatment duration and stage of clinical ...
Matteo Monami +2 more
wiley +1 more source
Decoding incretin resistance: a mechanistic framework to reclassify therapeutic variability for GLP-1 receptor agonist therapy. [PDF]
Fajkić A, Lam YW, Belančić A.
europepmc +1 more source
JNK3 regulates β cell responses to incretins in human islets and mouse models. [PDF]
Louzada RA +10 more
europepmc +1 more source
Tirzepatide for Excess Weight in Adults With Type 1 Diabetes Using MiniMed 780G
Diabetes, Obesity and Metabolism, Volume 28, Issue 9, Page 8709-8713, September 2026.
Michelantonio De Fano +6 more
wiley +1 more source
Implications of GLP-1 Agonists on Office-Based Sedation and General Anesthesia for Dentistry. [PDF]
McKenzie C, DeBernardo A, Schwartz P.
europepmc +1 more source
Effect of GIP and GLP-1 infusion on bone resorption in glucose intolerant, pancreatic insufficient cystic fibrosis. [PDF]
Lei WS +7 more
europepmc +1 more source
A Critical Analysis of the Clinical Use of Incretin-Based Therapies: Efficacy and Adverse Events. [PDF]
Radparvar I, Agrawal DK.
europepmc +1 more source
Incretins in the Therapy of Diabetic Kidney Disease [PDF]
Diabetic kidney disease is a microvascular complication that occurs in patients with diabetes. It is strongly associated with increased risk of kidney replacement therapy and all-cause mortality.
Andrzej Pawlik, Weronika Bielka
exaly +2 more sources

