Results 51 to 60 of about 2,629,038 (335)
Stochastic Modelling Approach to the Incubation Time of Prionic Diseases
Transmissible spongiform encephalopathies like the bovine spongiform encephalopathy (BSE) and the Creutzfeldt-Jakob disease (CJD) in humans are neurodegenerative diseases for which prions are the attributed pathogenic agents.
A. S. Ferreira +15 more
core +1 more source
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile +8 more
wiley +1 more source
Net primary productivity (NPP) is a crucial indicator of ecosystem function and sustainability. Quantifying the response of NPP to phenological dynamics is essential for understanding the impact of climate change on ecosystem processes.
Jiale Wang +6 more
doaj +1 more source
Formation of nanocrystals based on decomposition in the amorphous Zr41.2Ti13.8Cu12.5Ni10Be22.5 alloy [PDF]
Primary crystallization and decomposition in the bulk amorphous alloy Ar41.2Ti13.8Cu12.5Ni10Be22.5 have been studied by small angle neutron scattering (SANS), transmission electron microscopy (TEM), and differential scanning calorimetry (DSC).
Johnson, W. L. +2 more
core +1 more source
Phytohormone brassinosteroid‐induced gene regulation by the transcription factor BIL1/BZR1 involves redox‐dependent DNA‐binding alternation and interaction with the transcription factor PIF4. The reduced BIL1/BZR1 dimer binds preferred cis‐elements, while oxidation alters its oligomerization state and disrupts DNA‐binding ability.
Shohei Nosaki +4 more
wiley +1 more source
Influence of incubation temperature on morphology and locomotion performance of Leatherback (Dermochelys coriacea) hatchlings [PDF]
The journey of Leatherback (Dermochelys coriacea (Vandelli, 1761)) hatchlings from nest to the sea is a vulnerable life-history stage. Studies have shown that nest incubation temperatures influence hatchling morphology and locomotor performance, which ...
Downie, J.R., Mickelson, L.E.
core +1 more source
Structural dynamics of the plant hormone receptor ETR1 in a native‐like membrane environment
The present study unveils the structural and signaling dynamics of ETR1, a key plant ethylene receptor. Using an optimized nanodisc system and solution NMR, we captured full‐length ETR1 in a native‐like membrane environment. Our findings reveal dynamic domain uncoupling and Cu(I)‐induced rigidification, providing the first evidence of metal‐triggered ...
Moritz Lemke +2 more
wiley +1 more source
Sharing the burden : on the division of parental care and vocalizations during incubation [PDF]
In species with biparental care, individuals only have to pay the costs for their own parental investment, whereas the contribution of their partner comes for free. Each parent hence benefits if its partner works harder, creating an evolutionary conflict
Kavelaars, Marwa M. +2 more
core +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source

