Results 61 to 70 of about 281,431 (254)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Isolation and identification of versatile Bacillus aryabhattai and their effect on plant growth promotion and essential oil yield in Eryngium foetidum L

open access: yesDiscover Plants
Eryngium foetidum L. is a promising horticultural crop known for its numerous medicinal properties. Therefore, cultivating E. foetidum L. using sustainable practices is essential, which can be achieved by modifying the rhizospheric architecture of the ...
V. Sadhana   +3 more
doaj   +1 more source

Incubation of the ostrich [PDF]

open access: yesNature, 1883
I HAVE received the following letter from Mr. J. E. Harting, and with his permission send it to you for publication. I do so partly in justice to Mr. Harting himself—the letter having been originally written to the Spectator in vindication of his own accuracy, and having been rejected by the editor—and partly because I think it desirable that the point
openaire   +2 more sources

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Storage of Hatching Eggs : Effects of storage and early incubation conditions on egg characteristics, embryonic development, hatchability, and chicken quality [PDF]

open access: yes, 2010
Key words: egg storage, embryonic development, albumen quality, hatchability, chick quality It is well known that an increase in the storage duration increases incubation duration and decreases hatchability and chick quality.
Reijrink, I.A.M.
core  

Measuring School Principals’ Well-Being: Validation of an Instrument

open access: yesEducation Sciences
The article reports on the development and validation of an instrument to measure the well-being of public-school principals in Gauteng, South Africa, based on a specific theoretical framework. Adopting a quantitative, post-positivist paradigm, data were
Naadira Adamjee   +2 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

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