Results 41 to 50 of about 4,871 (254)
The Journal of Physiology, EarlyView.Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich +9 more
wiley +1 more source
Research progress of donepezil for treating mild to moderate Alzheimer's disease
Chinese Journal of Contemporary Neurology and Neurosurgery, 2017 Donepezil is the second generation of cholinesterase inhibitors (ChEIs), which has a good effect on mild to moderate Alzheimer's disease (AD). In recent years, there were a lot of studies on the mechanism of donepezil. This paper mainly introduces the
Xin-xin LI, Yun-yun ZHANG, Bin WANG
doaj
A General Strategy for C(sp3)─H Bond Etherification via Quinoline Derivative‐Mediated Electrolysis
Advanced Science, Volume 12, Issue 22, June 12, 2025.A quinoline‐based mediator is introduced for the electrochemical etherification of C(sp3)─H bonds, enabling the process with minimal dependence on substrate electronic properties. The reaction demonstrates compatibility with various C─H bonds, including tertiary benzylic C─H bonds and unactivated C(sp3)─H bonds.
Yousen Xu +4 more
wiley +1 more source
Advanced Synthesis &Catalysis, Volume 367, Issue 8, April 15, 2025.Abstract The manuscript describes a formal [10+2] higher‐order cycloaddition between 2‐arylideneindan‐1‐ones and α‐alkylidene azlactones as higherene precursors and higherenofiles respectively. The reaction is realized under Brønsted‐base catalysis utilizing the phase transfer catalysis approach.
Joanna Dybowska +3 more
wiley +1 more source
Examining the regulatory value of multi-route mammalian acute systemic toxicity studies [PDF]
, 2011 Regulatory information requirements for pesticides call for submission of acute systemic toxicity data for up to three different exposure routes (oral, dermal, inhalation) for both active ingredients and formulated products.
BULGHERONI Anna +2 more
core
Chemistry – A European Journal, Volume 31, Issue 11, February 20, 2025.Little explored are 1,3,5‐triazine cores that are substituted with three different heteroaromatic groups despite their distinct optical and electronic properties. 1,3,5‐Triazines substituted with strong donor and acceptor thiophenes give rise to long wavelength absorption tails due to intramolecular charge transfer absorptions of the meta‐conjugated ...
Jacob G. Rothera +9 more
wiley +1 more source
Progress Toward Replacing Animals in Toxicity Testing for Cosmetics [PDF]
, 2012 In the 1980’s, animal rights activists successfully motivated the cosmetic industry to begin researching alternatives to animal tests.
Nye, Marisa B.
core
Chemistry – A European Journal, Volume 30, Issue 69, December 10, 2024.In the organophosphine chemistry, the typical reaction is initiated through the β‐addition of phosphine to allenoates or alkynoates. This paper reports an unprecedented reactivity of 1,3‐enynoates and indane‐1,3‐diones in the presence of phosphines.
Szu‐Han Chen +5 more
wiley +1 more source
Green Electrochemical Sensors, Their Applications and Greenness Metrics Used: A Review
Electroanalysis, Volume 36, Issue 11, November 2024.Abstract Green analytical methods are important techniques that aim to reduce or eliminate the use of harmful chemicals and waste in various analyses. These methods, based on green chemistry principles, are environmentally friendly and reliable. Electrochemical techniques have an essential role in diverse analyses, and are presented as a superior ...
Caglar Berkel, Oguz Özbek
wiley +1 more source
European Journal of Inorganic Chemistry, Volume 27, Issue 25, September 2, 2024.Dinuclear cobalt(III) complexes have been isolated with the bridging thean− bis(dioxolene) ligand in the cat2−‐cat2−, cat2−‐SQ⋅− and SQ⋅−‐SQ⋅− states (theaH4=2,3,6,7‐tetrahydroxy‐9,10‐dimethyl‐9,10‐dihydro‐9,10‐ethanoanthracene, cat2−=catecholate, SQ⋅−=semiquinonate).
Jett T. Janetzki +5 more
wiley +1 more source