Results 91 to 100 of about 10,572 (203)
A Molecular Hybridization Approach for the Design of Potent, Highly Selective, and Brain-Penetrant N-Myristoyltransferase Inhibitors [PDF]
, 2018 Crystallography has guided the hybridization of two series of Trypanosoma brucei N-myristoyltransferase (NMT) inhibitors, leading to a novel highly selective series.
Brand, Stephen +18 more
core +3 more sources
N-(3-Chloro-1-methyl-1H-indazol-5-yl)-4-methylbenzenesulfonamide
Acta Crystallographica Section E, 2014 The asymmetric unit of the title compound, C15H14ClN3O2S, contains two independent molecules showing different conformations: in one molecule, the indazole ring system makes a dihedral angle of 51.5 (1)° with the benzene ring whereas in the other, the ...
Hakima Chicha +4 more
doaj +1 more source
A straightforward synthesis of indazolo[3,2-a]isoquinolin-6-amines [PDF]
, 2013 4-Substituted 1-bromoisoquinolin-3-amines were subjected to Suzuki coupling with o-nitrophenylboronic acid to yield 1-(2-nitrophenyl) isoquinolinamines, which participated in Cadogan cyclization with triethyl phosphite under microwave irradiation in a ...
Balog, József +2 more
core +1 more source
1-(3-Chloro-6-nitro-1H-indazol-1-yl)ethan-1-one
IUCrData, 2017 The asymmetric unit of the title compound, C9H6ClN3O3, contains one full molecule in a general position and a half molcule sitting on a crystallographic mirror plane.
Mohamed Mokhtar Mohamed Abdelahi +5 more
doaj +1 more source
Chemical composition of Nigella sativa Linn : Part 2 Recent advances [PDF]
, 2016 The black cumin or Nigella sativa L. seeds have many acclaimed medicinal properties such as bronchodilatory, hypotensive, antibacterial, antifungal, analgesic, anti-inflammatory and immunopotentiating.
Afzal, M, Khan, Akram
core +1 more source
1-(6-Nitro-1H-indazol-1-yl)ethanone
IUCrData, 2017 In the title molecule, C9H7N3O3, the indazole moiety is essentially planar and the mean plane of the acetyl substituent is twisted by 5.3 (1)° from its plane.
Mohamed Mokhtar Mohamed Abdelahi +5 more
doaj +1 more source
Pharmacological activities of ruthenium complexes related to their NO scavenging properties [PDF]
, 2016 Angiogenesis is considered responsible for the growth of primary tumours and of their metastases. With the present study, the effects of three ruthenium compounds, potassiumchlorido (ethylendiamminotetraacetate)rutenate(III) (RuEDTA), sodium (bis ...
Bergamo, Alberta +3 more
core +2 more sources
Crystal structure of (E)-3-[(2,6-dimethylphenyl)diazenyl]-7-methyl-1H-indazole
Acta Crystallographica Section E: Crystallographic Communications, 2018 The title azo compound, C16H16N4, was synthesized from 2,6-dimethylaniline. The diazenyl group adopts a trans (E) conformation, with an N=N bond length of 1.265 (4) Å. The pyrazole ring is approximately planar.
Shiomi Yagi +2 more
doaj +1 more source
Chalcones as versatile synthons for the synthesis of 5- and 6-membered nitrogen heterocylces [PDF]
, 2014 Chalcones belong to the flavonoid family which constitutes one of the major classes of naturally occurring oxygen heterocyclic compounds. The alpha,beta-unsaturated carbonyl system of chalcones possesses two electrophilic reactive centers allowing them ...
Albuquerque, Hélio +3 more
core +1 more source
1-(5-Nitro-1H-indazol-1-yl)ethanone
IUCrData, 2016 In the title compound, C9H7N3O3, paired ribbons of molecules running in the a-axis direction are formed by intermolecular C—H...O and offset π-stacking interactions.
Mohammed Boulhaoua +4 more
doaj +1 more source