Results 81 to 90 of about 5,024 (202)
ChemCatChem, Volume 18, Issue 4, 25 February 2026.A series of ketimines were synthesized via electrophilic aromatic substitution on indole and pyrrole derivatives. This synthetic method is based on activating amides using PIII/PV═O redox catalysis, yielding an imidoyl chloride intermediate. Subsequent conversion with indole and pyrrole derivatives afforded 20 novel ketimines in yields up to 94 ...
Viktorija Medvarić +2 more
wiley +1 more source
Photo- and electro-chemical strategies for indazole synthesis
Tetrahedron ChemThe indazole core is prevalently found in the structures of bioactive molecules, demonstrating promising potential in medicinal chemistry and drug discovery, which therefore has attracted sustained attention from the synthetic community.
Binbin Huang
doaj +1 more source
Synthesis of azole biophospanates presursors for proton-exchange membrane for application in high temperature PEM fuel cells [PDF]
, 2011 This work reports the synthesis and characterization of phosphonate-, hydroxybisphosphonate- and aminobisphosphonatebenzimidazole derivatives substituted at N-1 position and new regioisomers phosphonateand aminobisphosphonatebenzotriazole derivatives ...
Rangel, C. M., Teixeira, Fatima
core
, 2014 International audienceThe solvent is certainly one of the main sources of wastes during palladium-catalysed direct arylation reactions. We found that such direct arylations of heteroaromatics can be performed using very high concentrations of reactants ...
Bensaid, Souhila, Doucet, Henri
core +3 more sources
Recent Contributions of Organic Synthesis to Forensic Science
ChemPlusChem, Volume 91, Issue 2, February 2026.Forensic science is a multidisciplinary field that plays a vital role in providing scientific evidence for criminal investigations. This review highlights advances and opportunities at the interface between organic synthesis and forensic science, with applications in drug identification, forensic toxicology, and latent fingerprint detection and ...
Gustavo dos Santos Martins +3 more
wiley +1 more source
High Throughput Screening of a GlaxoSmithKline Protein Kinase Inhibitor Set Identifies an Inhibitor of Human Cytomegalovirus Replication that Prevents CREB and Histone H3 Post-Translational Modification. [PDF]
, 2017 To identify new compounds with anti-human cytomegalovirus (HCMV) activity and new anti-HCMV targets, we developed a high throughput strategy to screen a GlaxoSmithKline (GSK) Published Kinase Inhibitor Set (PKIS).
Ho, CMK +5 more
core +3 more sources
Rapid Identification of New Psychoactive Substances in Letters by LA‐APCI‐MS
Drug Testing and Analysis, Volume 18, Issue 2, Page 198-206, February 2026.Laser ablation coupled to molecular mass spectrometry utilizing a modified atmospheric pressure chemical ionization source was used for the detection of synthetic cannabinoid receptor agonists in infused prison mail samples. ABSTRACT New psychoactive substances (NPS), especially synthetic cannabinoid receptor agonists (SCRA), are increasingly smuggled ...
Mark Wesner +4 more
wiley +1 more source
High temperature pyrolysis of solid products obtained from rapid hydrothermal pre-processing of pinewood sawdust [PDF]
, 2014 A sample of pinewood sawdust was rapidly pre-processed in a torrefaction-type procedure, separately in subcritical water (neutral) and with added Na2CO3 (alkaline compound) and Nb2O 5 (solid acid) in a batch reactor.
Almeida +28 more
core +1 more source
Drug Testing and Analysis, Volume 18, Issue 2, Page 222-229, February 2026.A novel software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances was developed and applied to mimic the metabolism of the synthetic cannabinoid receptor agonist MDMB‐4en‐PINACA. ABSTRACT An innovative software tool for the rapid and efficient simulation of the metabolism of new psychoactive substances (NPS ...
Mark Wesner +3 more
wiley +1 more source
Molecules, 2006 A series of indazoles substituted at the N-1 and N-2 positions with ester-containing side chains -(CH2)nCO2R of different lengths (n = 0-6, 9, 10) are described.Nucleophilic substitution reactions on halo esters (X(CH2)nCO2R) by 1H-indazole inalkaline ...
Isabel Bento +5 more
doaj +1 more source