Results 81 to 90 of about 74,170 (261)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Evaluation Of The Implementation Of The Independent Curriculum

Eduvest - Journal of Universal Studies
The implementation of the Independent Curriculum in driving schools is a strategic step by the Ministry of Education and Culture in facing the challenges of the 21st century, which emphasizes competency-based learning, differentiation, and character. In this context, the subjects of Physical Education, Sports, However, the implementation of this new ...
openaire   +1 more source

ACHIEVE THE IMPLEMENTATION OF THE INDEPENDENT CURRICULUM THROUGH THE INDEPENDENT TEACHING PLATFORM

JENTRE
Penelitian ini sebagai penyeimbang terhadap pelaksanaan program sekolah dan guru penggerak, yaitu program pemerintah untuk memahamkan dan mengimplementasikan kurikulum merdeka. Platform merdeka mengajar (PMM) yang digelar oleh kementerian pendidikan dan kebudayaan, yang pelaksanaannya dilaksanakan secara daring juga dilaksanakan untuk memahamkan para ...
Titim Kurnia, Kirana Qurotal Aini Prawira   +1 more
openaire   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

FEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell, Cassy Ross, Panagiota S. Filippou, Bruno Silvester Lopes, Dominic Gilchrist, Paul Dean, Kamar Ameen‐Ali, Tora K. Smulders‐Srinivasan, Ahmad A. Khundakar   +8 more
wiley   +1 more source

Learning innovation: Reconstruction laboratory activities design on respiratory air and designing a simple spirometer

Bio-Inoved: Jurnal Biologi-Inovasi Pendidikan
Laboratory practicum in science learning is considered important, especially in the context of the Independent Curriculum. Science-based learning is needed to encourage the development of students' skills and character, supported by practical activities.
Solikhah Isti Fadilah, Bambang Supriatno, Alfyn Abdan Nurahman, Amprasto Amprasto   +3 more
doaj   +1 more source

Implementation of Holistic Learning in the Independent Curriculum

Social, Humanities, and Educational Studies (SHES): Conference Series
<p>Pembelajaran holistik mempunyai peranan penting dalam mencapai tujuan penerapan kurikulum merdeka. Pembelajaran ini sangat penting untuk dilaksanakan, namun belum sepenuhnya diterapkan pada kurikulum merdeka. Penelitian ini membahas bagaimana penerapan pembelajaran holistik dalam kurikulum merdeka melalui pembelajaran intrakurikuler ...
Astuti Yuniati, Sri Marmoah, Kartika Chrysti Suryandari   +2 more
openaire   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Implementation of the Merdeka Curriculum in Learning Supervision for Inclusion Programs in Primary Education

Jurnal Abdimas Cendekiawan Indonesia
This community service aims to socialize the implementation of the Merdeka Curriculum for learning supervision in inclusion service programs in education units.
Meyritha Trifina Sari, Dian Yunitasari, Achmad Supriyanto, Kim Leah   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

FEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton, Fang Zhao, Reeta Davis, Meg Walsh, Kevin E O'Connor, David O'Connell, Tanja Narancic   +6 more
wiley   +1 more source

Implementation of Independent Curriculum Policy in Facing the Society 5.0 Era

Jurnal Ilmiah Ilmu Administrasi Publik
The rapid development of technology in the era of society 5.0 is characterized by the rapid pace of information technology, this also makes various challenges appear in various aspects, one of which is education.
Julizar Idris, Jumanah Jumanah, Ira Rahmawati, Marlina Marlina, Nurlinda Nurlinda   +4 more
doaj   +1 more source