Results 81 to 90 of about 2,686,565 (303)

Territorial aggression and coexistence in hybridizing Campylorhynchus: disentangling the roles of climate, resource availability, and species interactions in western Ecuador

Journal of Avian Biology
Interspecific territoriality is a prevalent form of interference competition among animals across environments. However, the connections between interspecific territorial aggression and other related aspects such as hybridization and climate remain ...
Luis Daniel Montalvo, Rebecca T. Kimball, Scott K. Robinson   +2 more
doaj   +1 more source

Direct and Indirect Effects of Public Infrastructure on Regional Economic Growth in Japan: An Application of the Covariance Structure Model by Geographical Classification Area [PDF]

The direct and indirect effects of public infrastructure (PI) were evaluated by a covariance structure model. Empirical results showed the positive indirect effect, crowding-in effect, as well as the direct effect as an input factor, differences of these
Kunimitsu, Yoji
core   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Threshold levels and the realization of a group benefit [PDF]

This paper considers a voluntary contribution threshold game in which a group benefit is realized only if the number of contributors at least reaches a threshold level, and analyzes the effect of the threshold level on the likelihood that the group ...
Xiaopeng Xu
core  

Approximate properties of the response of nonlinear dynamic systems to stochastic inputs [PDF]

, 1971
Indirect method considers effect of nonlinearity and obtains approximate probability densities of certain characteristics, from these densities various statistical properties are calculated. Direct method determines response moments directly.
Zirkle, L. D.
core   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Indirect effects of leadership behaviors on departmental performance via organizational learning in Ethiopian public research universities

Cogent Education
There are myriads of research outputs regarding the nexus between leadership behaviors and organizational effectiveness. Nonetheless, there is a scarcity of empirical studies examining the indirect effect of leadership behaviors on academic performance ...
Wakgari Tasisa Duressa, Befekadu Zeleke Kidane   +1 more
doaj   +1 more source

Study on character association in Lens culinaris medik.

Electronic Journal of Plant Breeding, 2021
A field trial with fifty genotypes of lentil was undertaken in Agriculture Farm of the Institute of Agriculture, Visva –Bharati University during two consecutive winters of the year 2017-18 and 2018-19, with an intention to find out the nature of the ...
Soumya Satpathy*, Sandip Debnath and Abinash Mishra
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source