Results 111 to 120 of about 173,002 (293)

A Low‐Cost, Handheld Optical Stiffness Sensor for Minimally Invasive Surgery

open access: yesAdvanced Robotics Research, EarlyView.
A novel handheld stiffness sensor is presented for real‐time tissue stiffness characterization. By simultaneously sensing contact force and tissue deformation, the device enables accurate stiffness quantification without requiring precise manual control. This approach offers a promising solution for intraoperative tumor detection and minimally invasive
Qianyu Ma   +4 more
wiley   +1 more source

Effects of Direct and Indirect Written Corrective Feedback on French Writing Skills: A Comparative Study

open access: yesInternational Journal of Education
This study aims to examine the impact of implementing direct and indirect written corrective feedback on the enhancement of French writing skills. The research employed a quantitative approach utilizing a static-group pretest-posttest design.
Alifia Jihan Anandani Bima   +2 more
doaj   +1 more source

Malectin Alleviates Endoplasmic Reticulum Stress in Gestational Diabetes Mellitus via Glycoprotein Quality Control Mechanisms

open access: yesAdvanced Science, EarlyView.
Malectin alleviates high glucose‐induced ER stress and damage in placental trophoblasts, a function dependent on its six critical carbohydrate‐binding residues. In a GDM mouse model, administration of TAT‐Malectin ameliorated hyperglycemia and placental ER stress and prevented fetal macrosomia.
Jiahui Zhu   +12 more
wiley   +1 more source

THE COMPARATIVE STUDY BETWEEN TEACHERS DIRECT AND INDIRECT FEEDBACK TECHNIQUES IN IMPROVING STUDENTS WRITING RECOUNT TEXT AT SMAN 1 KOTAGAJAH [PDF]

open access: yes, 2017
Penelitian ini bertujuan untuk meneliti apakah i) teknik teachers direct feedback dapat meningkatkan kemampuan menulis siswa, ii) teknik teachers indirect feedback dapat meningkatkan kemampuan menulis siswa, dan iii) apakah ada perbedaan pada kemampuan ...
Yufrizal, Hery   +2 more
core  

Charting Uncharted Waters: AI-Driven Feedback and Writing Accuracy of Intermediate Iranian EFL Learners

open access: yesResearch in English Language Pedagogy
This study explored the impact of AI-driven feedback on the writing accuracy of Iranian intermediate EFL learners using a quasi-experimental design.
Mohsen Banisharif Dehkordi   +2 more
doaj  

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

open access: yesAdvanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang   +19 more
wiley   +1 more source

Cross Kingdom Metabolic Engineering Paradigm Elevating Sustainable Protein Production

open access: yesAdvanced Science, EarlyView.
ABSTRACT Confronting the dual crisis of escalating global protein demand and unsustainable agriculture necessitates transformative solutions. Here, we pioneer evolutionary insights from maize nitrogen optimization via asparagine synthetase (ASNS) to rewire metabolism in Pichia pastoris.
Yuanyuan Du   +4 more
wiley   +1 more source

Exploring the mediating effect of feedback self-efficacy between students’ self-feedback behavior and academic proficiency

open access: yesFrontiers in Psychology
Self-feedback and feedback self-efficacy are imperative components of self-regulated learning; few studies have investigated their combined impacts on academic achievement.
Yongle Yang   +6 more
doaj   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang   +16 more
wiley   +1 more source

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