Results 51 to 60 of about 2,266,638 (297)

Motivation and Organizational Culture on Performance with Self-efficacy Mediation [PDF]

open access: yes, 2016
The study aims to determine firstly the direct effect of motivation on performance,secondly the indirect effect of motivation on performance mediated by self efficacy, thirdlythe direct influence of organizational culture on the performance, and lastly ...
Heriningsih, S. (Sucahyo)   +1 more
core   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Teaching Grammar in Iraqi Secondary Schools by Using the Communicative Approach [PDF]

open access: yesScientific Bulletin of the Politehnica University of Timişoara: Transactions on Modern Languages, 2022
The aim of the present paper is to describe the teaching grammar process in Iraqi secondary schools based on the Communicative Approach (CA) with reference to teacher’s experience and the difficulties that the teachers face during teaching the class ...
Mohamed Ramadhan HASHIM
doaj  

Indirect methods for wake potential integration [PDF]

open access: yesPhysical Review Special Topics - Accelerators and Beams, 2006
The development of the modern accelerator and free-electron laser projects requires to consider wake fields of very short bunches in arbitrary three dimensional structures. To obtain the wake numerically by direct integration is difficult, since it takes a long time for the scattered fields to catch up to the bunch.
openaire   +4 more sources

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Radiative capture reactions via indirect methods

open access: yesPhysical Review C, 2017
In this paper we address the indirect method, which can provide a powerful technique to obtain information about radiative capture reactions at astrophysically relevant energies. The idea of the indirect method is to use the indirect reaction $A(a, s\, )F$ to obtain information about the radiative capture reaction $A(x,\, )F$, where $a=(s\,x)$ and $F=
Mukhamedzhanov, A. M., Rogachev, G. R.
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

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