Results 21 to 30 of about 13,763,316 (290)

Indirect treatment comparison of lanadelumab and a C1-esterase inhibitor in pediatric patients with hereditary angioedema [PDF]

open access: yesJournal of Comparative Effectiveness Research
Aim: To compare the efficacy and safety of lanadelumab versus other approved long-term prophylaxis (LTP) treatments in patients with pediatric hereditary angioedema (HAE) aged
Maureen Watt   +3 more
doaj   +2 more sources

Monoclonal antibodies against calcitonin gene-related peptide in chronic migraine: an adjusted indirect treatment comparison [PDF]

open access: yes, 2020
Objective:New monoclonal antibodies against the calcitonin generelated peptide pathway have recently been developed for the prevention of migraine.
Manuel David Gil-Sierra   +4 more
core   +5 more sources

Indirect and mixed treatment comparisons in arthritis research [PDF]

open access: yesRheumatology, 2011
Evidence for the efficacy of biologic therapies in inflammatory arthritis comes overwhelmingly from placebo-controlled trials. Increasingly, however, authorities responsible for purchasing and reimbursement have tried to determine whether there are differences between these powerful new therapies, which would lead them to recommend some in preference ...
Ades, Anthony E.   +2 more
openaire   +3 more sources

Indirect treatment comparison of nivolumab versus placebo for the adjuvant treatment of melanoma [PDF]

open access: yesEuropean Journal of Cancer, 2020
Until recently, adjuvant treatment options for stage III and IV resectable melanoma have been limited. Patients were often managed through routine surveillance. The phase III randomised controlled trial (RCT) CheckMate 238 (238) demonstrated the safety and efficacy of nivolumab as an adjuvant treatment for melanoma in patients with stage IIIB/C or IV ...
Matthew Hemstock   +7 more
openaire   +2 more sources

Statistical Methods for Aggregation of Indirect Information [PDF]

open access: yes, 2015
How to properly aggregate indirect information is more and more important. In this dissertation, we will present two aspects of the issue: indirect comparison of treatment effects and aggregation of ordered-based rank data ...
Han, Simeng
core   +6 more sources

Effect modification in anchored indirect treatment comparison: Comments on “Matching‐adjusted indirect comparisons: Application to time‐to‐event data”

open access: yesStatistics in Medicine, 2022
This commentary regards a recent simulation study conducted by Aouni, Gaudel-Dedieu and Sebastien, evaluating the performance of different versions of matching-adjusted indirect comparison (MAIC) in an anchored scenario with a common comparator. The simulation study uses survival outcomes and the Cox proportional hazards regression as the outcome model.
Antonio Remiro‐Azócar   +2 more
openaire   +4 more sources

Indirect Treatment Comparison of Biologics in Chronic Rhinosinusitis with Nasal Polyps

open access: yesThe Journal of Allergy and Clinical Immunology: In Practice, 2021
Among patients with chronic rhinosinusitis with nasal polyps (CRSwNP), randomized clinical trials (RCTs) of biologics, such as anti-interleukin-4/interleukin-13 (dupilumab) and anti-immunoglobulin E (omalizumab), have demonstrated efficacy compared with intranasal corticosteroids (INCS).
Peters, Anju T.   +12 more
openaire   +3 more sources

Indirect treatment comparison of nivolumab versus placebo as adjuvant treatment for resected melanoma [PDF]

open access: yesEuropean Journal of Cancer, 2021
Nivolumab (an anti-programmed death-1 antibody) is an adjuvant standard of care for patients with high-risk resected melanoma, although a watch-and-wait strategy remains an option. In the absence of head-to-head evidence, an indirect treatment comparison (ITC) of adjuvant nivolumab versus placebo, the proxy for a watch-and-wait strategy, was conducted ...
Jeffrey S. Weber   +10 more
openaire   +3 more sources

International Comparison of Constitutional Reform Processes in Terms of the Requirements of Indirect and Direct Democracy

open access: yes, 2023
This paper is an international comparison of the requirements for indirect and direct democracy in the constitutional revision process. It aims to examine whether a “comparison with other countries’ constitutional revision procedures” is a valid basis ...
Takashi Kitamura
core   +1 more source

A Response to “Letter to the Editor Regarding ‘Dupilumab Versus Lebrikizumab Demonstrates Greater Likelihood of Achieving and Maintaining Improvements in Efficacy Outcomes Using a Placebo-Adjusted Indirect Treatment Comparison’” [PDF]

open access: yesDermatology and Therapy
Sonja Ständer   +11 more
doaj   +2 more sources

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