Results 31 to 40 of about 3,427 (196)
Antioxidants, 2021 Efficient drugs are needed for countering the worldwide high incidence of cutaneous squamous cell carcinoma (cSCC) and actinic keratosis. Indirubin derivatives represent promising candidates, but their effects in cSCC cells have not been reported before.
Jiaqi Zhu +3 more
doaj +1 more source
Über 6.6′‐Dibrom‐indirubin [PDF]
Berichte der deutschen chemischen Gesellschaft, 1912 n ...
Ettinger, L., Friedlaender, P.
openaire +2 more sources
Indirubin derivative E804 inhibits angiogenesis [PDF]
BMC Cancer, 2012 It has previously been shown that indirubin derivative E804 (IDR-E804) blocks signal transducer and activator of transcription-3 signaling in human breast and prostate cancer cells and inhibits Src kinase activity. To further establish its role in angiogenesis, we tested its potential using human umbilical vein endothelial cells (HUVECs) and analyzed ...
Shin, Eun-Kyung, Kim, Jin-Kyung
openaire +4 more sources
Nutrition & Metabolism, 2020 Background Obesity occurs when the body’s energy intake is constantly greater than its energy consumption and the pharmacological enhancing the activity of brown adipose tissue (BAT) and (or) browning of white adipose tissue (WAT) has been considered ...
Gang Wei +5 more
doaj +1 more source
Photoreactivity of indirubin derivatives
Photochemical & Photobiological Sciences, 2008 Twenty-nine analogs of indirubin, an isomer of indigo, have been synthesized to optimize its promising kinase inhibitory scaffold. These compounds being also pigmented, have been tested for their photoreactivity. Absorption maxima were between 485 nm and 560 nm.
Olivier, D. +11 more
openaire +3 more sources
Über Sauerstoff‐Isologe homologer Indirubine [PDF]
Berichte der deutschen chemischen Gesellschaft, 1908 n ...
Fries, K., Finck, G.
openaire +2 more sources
Anticancer effects and antimetastatic mechanisms of novel indirubin derivatives [PDF]
, 2010 In this current study, we are investigating the influence of 6-bromo-indirubin-3’oxime (6BIO) and 7-bromo-indirubin-3’oxime (7BIO) on induction of apoptosis, cell proliferation, and anti-migratory effects in the well characterized pancreatic carcinoma L3.
Kressirer, Christine
core +1 more source
Indirubin Derivative 6BIO Suppresses Metastasis [PDF]
Cancer Research, 2013 Abstract While metastasis is the chief cause of cancer mortality, there nonetheless remains a lack of antimetastatic therapies that are clinically available. In this study, we present the indirubin derivative 6-bromo-indirubin-3′-oxime (6BIO) as a promising antimetastatic agent.
Simone, Braig +6 more
openaire +2 more sources
Synthese und Struktur-Aktivitätsuntersuchungen von Indirubin-Derivaten [PDF]
, 2007 Indirubin wurde als aktive Komponente einer aus der traditionellen chinesischen Medizin stammenden Wirkstoffmischung namens Danggui Longhui Wan identifiziert, welche sich unter anderem als ein wirksames Mittel gegen chronisch myeloische Leukämie (CML ...
Mühlbeyer, Stephan
core +2 more sources
Acta Societatis Botanicorum Poloniae, 2018 The macroscopic and microscopic morphologies and indigo and indirubin concentration of the traditional Chinese medicine herbs Isatis indigotica Fort., Polygonum tinctorium Ait., and Baphicacanthus cusia (Nees) Bremek, all commonly known as “daqingye ...
Yingjiao Zhang +8 more
doaj +1 more source