Results 51 to 60 of about 256,812 (272)

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Moving beyond IPS: a person-centred approach to social inclusion and mental health

BJPsych Bulletin
Many people experiencing mental ill health are trapped in cycles of worsening social exclusion. Individual Placement and Support (IPS) is being implemented to support those with mental ill health into employment.
Anna Greenburgh, Mark Bertram, Helen Baldwin, Shaun Williams, Sarah McDonald, Craig Morgan   +5 more
doaj   +1 more source

Learning the Principle of Zero Exclusion. Managers Challenging the Logic of Professionalism in Services for People with Psychosocial Disabilities

Scandinavian Journal of Disability Research, 2023
Individuals with psychosocial disabilities face substantial barriers that hinder their equal participation in working life, such as discrimination and lack of self-determination.
Line Fossum Skogstad
doaj   +1 more source

The potential of technology for enhancing individual placement and support supported employment. [PDF]

Psychiatric Rehabilitation Journal, 2014
The potential of technology to enhance delivery and outcomes of Individual Placement and Support (IPS) supported employment.IPS supported employment has demonstrated robust success for improving rates of competitive employment among individuals with psychiatric disabilities.
Sarah E, Lord, Susan R, McGurk, Joanne, Nicholson, Elizabeth A, Carpenter-Song, Justin S, Tauscher, Deborah R, Becker, Sarah J, Swanson, Robert E, Drake, Gary R, Bond   +8 more
openaire   +2 more sources

IPS: Individual Placement and Support. L’esperienza italiana [PDF]

, 2012
Cappa C., Fioritti A., IPS: Individual Placement and Support. L’esperienza italiana, Intervento a "Si può fare in azienda. Aziende, lavoro e disturbo psichico", Roma, 13 dicembre 2011. Isfol OA: Presentation.
Cappa, Corrado, Fioritti, Angelo
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Exploring the non-vocational outcomes of the individual placement and support (IPS) employment model [PDF]

Irish Journal of Occupational Therapy
Purpose – Individual Placement and Support (IPS) is an evidence-based employment model, effective in supporting individuals with severe mental health difficulties to gain competitive employment.
Leonie Boland, Michelle Kennedy, Lauren Jane Lynch, Meabh Bonham-Corcoran, Sarah Quinn   +4 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Vocational Service Models and Approaches to Improve Job Tenure of People With Severe and Enduring Mental Illness: A Narrative Review

Frontiers in Psychiatry, 2021
Employment is a valued occupation that offers a sense of meaning, identity, and belonging. For people with severe and enduring mental illness, employment has also been associated with personal recovery and decreased use of mental health services. However,
Caitlin McDowell, Caitlin McDowell, Caitlin McDowell, Priscilla Ennals, Priscilla Ennals, Priscilla Ennals, Ellie Fossey, Ellie Fossey   +7 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source