Results 81 to 90 of about 487,159 (190)

The emerging role of the Hippo signaling pathway in interorgan crosstalk

open access: yesThe FEBS Journal, EarlyView.
Hippo signaling functions as a central hub of interorgan communication. Systemic cues from the gut, adipose tissue, and skeletal muscle—including hormones, metabolites, and microbial signals—regulate YAP/TAZ activity in a tissue‐ and context‐dependent manner.
Gahyeon Song   +2 more
wiley   +1 more source

-benzyladenine and indole-3-butyric acid on photosynthetic apparatus of Orthosiphon stamineus plants grown in vitro

open access: yes, 2012
The leaf structure and chloroplast ultrastructure of kidney tea (Orthosiphon stamineus Benth.) was studied in in vitro culture on standard MS medium supplemented with or without plant growth regulators (PGRs).
V. Kapchina-Toteva   +3 more
core   +1 more source

Effects of Weight Loss Interventions on Gut Microbiota‐Derived Metabolites Linked to Cardiometabolic Health: A Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Background Gut microbiota‐derived metabolites are emerging as potential mediators between obesity and cardiometabolic conditions. While weight loss interventions modify microbiota composition, their effects on systemic microbial metabolites remain unclear.
Fernando Q. Iorra   +5 more
wiley   +1 more source

Exploring the biological impact of bacteria-derived indole compounds on human cell health: Cytotoxicity and cell proliferation across six cell lines

open access: yesToxicology Reports
Over the past two decades, research has increasingly focused on the interactions between diet, gut microbiota, and host organisms. Recent evidence suggests that tryptophan, an essential amino acid, can be metabolized by gut microbiota into indoles, which
Alisha Janiga-MacNelly   +4 more
doaj   +1 more source

Synthesis and characterization of 3-indole carboxylates of niobocene dichloride [PDF]

open access: yes, 1995
908-910The reaction of Cp2NbCI2 with sodium salts of 3-indole carboxylic acids viz. 3-indole carboxylic acid (ICNa), 3-indole acetlc acid (IANa), 3-indole propionic acid (IPNa), 3.-indole butyric acid (IBNa) and L-tryptophan (TRNa) in 1: 1 and 1:2 ratios
Sharma, Sangeeta   +3 more
core  

Indole-3-carboxylic acid

open access: yes, 2003
The crystal structure of indole-3-carboxylic acid, C9H7NO2, shows the presence of centrosymmetric hydrogen-bonded cyclic carboxylic acid dimers [OO = 2.649 (2) ŝ. These dimers are linked into a sheet structure through peripheral intermolecular hydrogen
Healy, Peter   +5 more
core   +1 more source

Interplay between gut microbiota and tryptophan metabolism in type 2 diabetic mice treated with metformin

open access: yesMicrobiology Spectrum
Tryptophan (TRP) metabolites have been identified as potent biomarkers for complications of type 2 diabetes mellitus (T2DM). However, it remains unclear whether the therapeutic effect of metformin in T2DM is related to the modulation of TRP metabolic ...
Yvhao Xie   +7 more
doaj   +1 more source

Indole-3-propionic Acid Attenuates HI-Related Blood–Brain Barrier Injury in Neonatal Rats by Modulating the PXR Signaling Pathway

open access: yes
The blood–brain barrier (BBB) is an important physiological barrier of the human body contributing to maintaining brain homeostasis and normal function. Hypoxic-ischemic (HI)-related brain injury is one of the main causes of neonatal acute morbidity and ...
Yan Nan (335311)   +11 more
core   +1 more source

The Gut Microbiota-Produced Indole-3-Propionic Acid Confers the Antihyperlipidemic Effect of Mulberry-Derived 1-Deoxynojirimycin

open access: yesmSystems, 2020
Hyperlipidemia has been intensively focused on by researchers around the world owing to its major contribution to cardiovascular diseases. Various evidence reveals that women are more susceptible than male counterparts to dyslipidemia, making sex-dependent therapeutic strategies and drugs urgently needed.
Yougui Li   +7 more
openaire   +3 more sources

Concentration difference of auxin involved in stem development in soybean

open access: yesJournal of Integrative Agriculture, 2020
Auxin regulates cell division and elongation of the primordial cells through its concentration and then shaped the plant architecture. Cell division and elongation form the internode of soybean and result in different plant heights and lodging resistance.
Zhen-feng JIANG   +6 more
doaj   +1 more source

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