Results 71 to 80 of about 487,159 (190)

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, EarlyView.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

Differences in the Profile of Aromatic Metabolites in the Corresponding Blood Serum and Cerebrospinal Fluid Samples of Patients with Secondary Bacterial Meningitis

Metabolites
Background: Secondary (nosocomial) bacterial meningitis remains a serious problem in patients with severe brain damage. The aim of this study was to assess the differences in the aromatic metabolites of tryptophan, phenylalanine, and tyrosine, in serum ...
Alisa K. Pautova, Peter A. Meinarovich, Vladislav E. Zakharchenko, Pavel D. Sobolev, Natalia A. Burnakova, Natalia V. Beloborodova   +5 more
doaj   +1 more source

Construction of an O2‐responsive engineering bioreactor for enhanced indole‐3‐propionic acid production and deoxynivalenol detoxification

Responsive Materials, EarlyView.
An oxygen‐responsive living bioreactor was engineered via interspecies protoplast fusion, converting oxygen from an inhibitory stress into a programmable signal for sustained indole‐3‐propionic acid (IPA) production. This genetically encoded bioreactor enables robust aerobic operation and therapeutic efficacy of deoxynivalenol detoxification in vivo ...
Ning Ma, Jiakun Shen, Kun Cai, Wenxi Zhao, Chuan Feng, Xingyao Wang, Yangyang Liu, Dongyan Zhang, Xi Ma   +8 more
wiley   +1 more source

Indole-3-propionic acid reduces lipid peroxidation induced by potassium iodate in porcine thyroid

Interdisciplinary Toxicology, 2021
Abstract Iodine is a trace element indispensable for thyroid hormone biosynthesis but its deficiency is a global problem. Programs of iodine prophylaxis are frequently based on salt iodization with the use of potassium iodate (KIO 3 ), which, however, reveals potential ...
Paulina Iwan, Malgorzata Karbownik-Lewinska   +1 more
openaire   +1 more source

Kaempferol Protects Intestinal Health in Chinese Forest Musk Deer Possibly by Regulating Intestinal Microbiota and Inhibiting the NF‐κB/NLRP3 Signaling Pathway

Integrative Zoology, EarlyView.
Kaempferol modulates the tryptophan metabolism pathway by increasing the abundances of Christensenellaceae R7 group, Bacteroides, and Blautia and reducing that of Rikenellaceae RC9 gut group, thereby significantly increasing the levels of ILA and IAA. This process inhibits the activation of NF‐κB/NLRP3 signaling pathway, reduces pro‐inflammatory factor
Xiangyu Liu, Zhanjun Ren, Xiuzhu Sun, Shuhui Wang   +3 more
wiley   +1 more source

Indole-3-acetic acid (IAA) Production from Sorghum Rhizosphere Bacteria in Ethiopia

, 2022
: Indole-3-acetic acid (IAA), a principal phytohormone, controls several crucial physiological processes of plants. Plant growth-promoting rhizobacteria (PGPR) are naturally occurring soil bacteria that can improve plant growth through phytohormone (IAA)
Birhanu Babiye
core   +1 more source

Potential role of indole-3-propionic acid in tuberculosis: current perspectives and future prospects

Expert Opinion on Therapeutic Targets
Indole-3-propionic acid (IPA), a tryptophan catabolite derived from gut bacterial metabolism, has been identified as a functional link between the gut microbiome and tuberculosis.IPA has gained ample attention over the past two decades on account of its multiple physiological roles, besides being both detectable and quantifiable.
Tejaswini Baral, Aieshel Serafin Johnson, Mazhuvancherry Kesavan Unnikrishnan, Mohan K. Manu, Kavitha Saravu, Chandrashekar Udyavara Kudru, Suhaj Abdulsalim, Jitendra Singh, Chiranjay Mukhopadhyay, Mahadev Rao, Sonal Sekhar Miraj   +10 more
openaire   +2 more sources

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

The FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi, Ayumu Takahashi, So Murakami, Nami Adachi, Tina Fujimoto, Yohta Fukuda, Taku Yamashita, Tsuyoshi Inoue, Hirofumi Tsujino   +8 more
wiley   +1 more source

Síntese e avaliação da atividade reguladora de crescimento vegetal de novos compostos indólicos derivados do safrol e relacionados ao ácido indol-3-acético [PDF]

, 2002
Tese (doutorado) - Universidade Federal de Santa Catarina, Centro de Ciências Físicas e Matemáticas. Programa de Pós-Graduação em Química.No presente trabalho explorou-se a reatividade do safrol e de seu derivado piperonal como materiais de partida para ...
Rosa, Flávia Aparecida Fernandes da
core  

Potent Enantioselective Auxin:  Indole-3-Succinic Acid

, 2016
Low levels of synthetic auxins are used as root growth promoters for a wide variety of botanicals. When properly used, they can produce earlier and more prolific root growth.
Charles F. Hammer (3009597), Charles L. Barnes (774654), Daniel W. Armstrong (1365207), Lingfeng He (2943162), Yan-Song Liu (3009594), K. Helen Ekborg-Ott (3009600)   +5 more
core   +1 more source