Results 11 to 20 of about 195,525 (279)
Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment [PDF]
, 2006 Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D ...
Elena P. Moiseeva (7583435) +4 more
core +7 more sources
When Is an Indole Not an Indole? [PDF]
Clinical Chemistry, 1998 An indole is not an indole when it is a naphthalene derivative! We routinely measure 5-hydroxyindoleacetic acid (5HIAA) by a long-established method using nitrosonaphthol, as first described by Udenfriend in 1955 (1), but with various modifications to improve specificity (2).
Kathryn Brownbill, John A Martin
openaire +1 more source
, 2008 Indole-3-carbinol enhances anti-proliferative, but not anti-invasive effects of oxaliplatin in colorectal cancer cell ...
Margaret M. Manson (7583447) +4 more
core +6 more sources
Synthesis of Bis(3‐indolyl)methanes Mediated by Potassium tert‐Butoxide
ChemistryOpen, 2023 The indole moiety is an important N‐heterocycle found in natural products, and a key structural component of many value‐added chemicals including pharmaceuticals. In particular, bis(3‐indolyl)methanes (BIMs) are an important subgroup of indoles, composed
A. Sofia Santos +5 more
doaj +1 more source
Bisindolyl Maleimides and Indolylmaleimide Derivatives—A Review of Their Synthesis and Bioactivity
Pharmaceuticals, 2023 The evolution of bisindolyl maleimides and indolyl maleimide derivatives and their unique biological activities have stimulated great interest in medicinal chemistry programs.
Louise N. Cooney +5 more
doaj +1 more source
, 2022 Antimicrobial resistant (AMR) bacteria are emerging and spreading globally, threatening our ability to treat common infectious diseases. The development of new classes of antibiotics able to kill or inhibit the growth of such AMR bacteria through novel ...
Malgorzata Wegrzyn (9382760) +13 more
core +5 more sources
Indole-ynones as Privileged Substrates for Radical Dearomatizing Spirocyclization Cascades
, 2022 Indole-ynones have been established as general substrates for radical dearomatizing spirocyclization cascade reactions. Five distinct and varied synthetic protocols have been developedcyanomethylation, sulfonylation, trifluoromethylation, stannylation ...
Jason M. Lynam +17 more
core +1 more source
The Emergence of Insect Odorant Receptor-Based Biosensors
Biosensors, 2020 The olfactory receptor neurons of insects and vertebrates are gated by odorant receptor (OR) proteins of which several members have been shown to exhibit remarkable sensitivity and selectivity towards volatile organic compounds of significant importance ...
Jonathan D. Bohbot, Sefi Vernick
doaj +1 more source
Microorganisms, 2021 Gut microbiota metabolizes tryptophan into indole, which can influence brain and behavior. Indeed, some oxidized derivatives of indole, formed in the liver, have neuroactive properties, and indole overproduction by the gut microbiota induces an anxio ...
Catherine Philippe +8 more
doaj +1 more source
, 2021 We report herein the facile synthesis of indole-fused six-, seven-, or eight-membered N,O-heterocycles through rhodium-catalyzed C–H acetoxylation/hydrolysis/annulation. The notable features of this method include C–H acetoxylation using NH-indole as the
Leipeng Lu +7 more
core +1 more source