Results 61 to 70 of about 19,941 (251)

Crystal structure of akuammicine, an indole alkaloid from Catharanthus roseus

open access: yesActa Crystallographica Section E: Crystallographic Communications, 2017
The title compound, C20H22N2O2, an alkaloid isolated from the Madagascar periwinkle, crystallizes in P1 with two independent but closely similar molecules in the unit cell. The molecules are linked into pairs by two N—H...O=C hydrogen bonds. The absolute
Mahdi Yahyazadeh   +4 more
doaj   +1 more source

Recent Advances in Bioconjugation of Aromatic Amino Acid Residues by a Reactivity‐Guided Approach

open access: yesThe Chemical Record, EarlyView.
This review highlights recent advances in the bioconjugation of aromatic amino acids residues, focusing on strategies that leverage their inherent chemical reactivity to enable precise and versatile modifications of biomacromolecules, illustrating relevant applications.
Bruno M. da S. Santos   +3 more
wiley   +1 more source

Is the endophyte‐based plant protection against aphids mediated by changes in the insect microbiome?

open access: yesInsect Science, EarlyView.
We showed that the fungal endophyte Epichloë strain AR37 increased the plant resistance against aphids via the production of indole diterpene alkaloids. The reduction in aphid performance was not associated with changes in abundance/composition/diversity of the insect's bacterial microbiota, but additional endophyte effects on this microbiota cannot be
Daniel A. Bastías   +5 more
wiley   +1 more source

Current Status of Indole-Derived Marine Natural Products: Synthetic Approaches and Therapeutic Applications

open access: yesMarine Drugs
Indole is a versatile pharmacophore widely distributed in bioactive natural products. This privileged scaffold has been found in a variety of molecules isolated from marine organisms such as algae and sponges.
Sergio Fernández   +3 more
doaj   +1 more source

Neuropsychopharmacology of hallucinogenic and non‐hallucinogenic 5‐HT2A receptor agonists

open access: yesBritish Journal of Pharmacology, EarlyView.
Psychedelic drugs such as LSD and psilocin were once relegated to the fringes of medical research because of their association with counterculture movements and a perceived concern about harm through recreational use, and their consequent legal prohibition in the early 1970s.
Trevor Sharp, Aurelija Ippolito
wiley   +1 more source

Unveiling the impact of nitrogen deficiency on alkaloid synthesis in konjac corms (Amorphophallus muelleri Blume)

open access: yesBMC Plant Biology
Background Konjac corms are known for their alkaloid content, which possesses pharmacological properties. In the primary cultivation areas of konjac, nitrogen deficiency is a common problem that significantly influences alkaloid synthesis.
Ying Qi   +7 more
doaj   +1 more source

Heterogeneity of iridoid biosynthesis in catmints: Molecular background in a phylogenetic context

open access: yesJournal of Integrative Plant Biology, EarlyView.
Evolutionary gains and losses of key biosynthetic genes likely resulting from multiple independent evolutionary events explain why certain Nepeta (catnip) species produce both the active, cat‐attracting nepetalactones and sugar‐bound iridoids, while others make only the sugar‐bound forms, and some have lost iridoid production entirely.
Tijana Banjanac   +15 more
wiley   +1 more source

Picranitine, a new indole alkaloid from Picralima nitida (Apocynaceae)

open access: yesBulletin of the Chemical Society of Ethiopia, 2002
A new indole alkaloid, picranitine, has been isolated from the seeds of Picralima nitida, along with five known indole alkaloids picratidine, akuammine, pseudoakuammine, akuammicine and akuammidine previously identified from the same source.
Pierre Tane, Mathieu Tene, Olov Sterner
doaj  

Synthetic Derivatives of Natural Alkaloid Harmine

open access: yesEurasian Chemico-Technological Journal, 2009
The indole alkaloid harmine was extracted from underground part of Peganum harmala L. With the purpose of obtaining the new biological active derivatives on base of alkaloid harmine the chemical modification was carried out.
M. M. Ismagulova   +4 more
doaj   +1 more source

The Jasmonate‐Responsive SmMPK3–SmWRKY33 Module Positively Regulates Tanshinone Biosynthesis in Salvia miltiorrhiza

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Tanshinones, the major bioactive diterpenes in Salvia miltiorrhiza Bunge, are widely used to treat cardiovascular and cerebrovascular diseases. While jasmonates (JAs) are known to modulate tanshinones accumulation, the molecular link between JA signalling and tanshinone biosynthesis remains unclear.
Renjun Qu   +9 more
wiley   +1 more source

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