Results 51 to 60 of about 30,006 (268)

Bifunctional Photocatalysts: Exploiting Proximity for Enhanced Reaction Performance

Chemistry – A European Journal, EarlyView.
This review covers the application of the bifunctional approach to photocatalysis as a means to attain (enhanced) enantioselectivity, and, more in general, as a strategy to enhance the catalytic performance through an effective use of short‐lived reaction intermediates.
Luigi Dolcini, Daniele Lavelli, Alberto Dal Corso, Luca Pignataro   +3 more
wiley   +1 more source

Indole alkaloid glycosides with a 1′-(phenyl)ethyl unit from Isatis indigotica leaves

Acta Pharmaceutica Sinica B, 2020
Seven indole alkaloid glycosides containing a 1′-(4″-hydroxy-3″,5″-dimethoxyphenyl)ethyl unit (1–7) were isolated from an aqueous extract of Isatis indigotica leaves (da qing ye).
Qinglan Guo, Dawei Li, Chengbo Xu, Chenggen Zhu, Ying Guo, Haibo Yu, Xiaoliang Wang, Jiangong Shi   +7 more
doaj   +1 more source

Transcriptome analysis of stem wood of Nothapodytes nimmoniana (Graham) Mabb. identifies genes associated with biosynthesis of camptothecin, an anti-carcinogenic molecule [PDF]

, 2016
Camptothecin (CPT), a monoterpene indole alkaloid, is a potent inhibitor of DNA topoisomerase I and has applications in treating ovarian, small lung and refractory ovarian cancers. Stem wood tissue of Nothapodytes nimmoniana (Graham) Mabb.
Kumar, Sanjay, Manunatha, BL, Nataraja, KN, Ravikanth, G, Shankar , R, Singh, HR, Uma Shaanker, R   +6 more
core   +1 more source

Monosubstituted N‐Arylhydroxylamine Chemistry: Integrating Contemporary Synthetic Approaches for the Efficient Construction of Diverse Heterocyclic Scaffolds

Chemistry – A European Journal, EarlyView.
Monosubstituted N‐arylhydroxylamines represent a unique subclass of hydroxylamines that act as pivotal intermediates in redox transformations and as versatile platforms for further synthetic transformations. They serve as key building blocks in the synthesis of architecturally complex heterocycles and other valuable organic compounds.
Michael G. Kallitsakis, Kyriakos D. Nikopoulos, Ioannis N. Lykakis   +2 more
wiley   +1 more source

Push–Pull Ynamines and Push–Pull Ynamides: Synthesis, Structure, Reactivity, and Application

European Journal of Organic Chemistry, EarlyView.
Push–pull ynamines and push–pull ynamides, which carry an EWG and an amino or amido group as EDG, are highly interesting classes of EDG‐EWG alkynes that have been intensively studied due to their exceptional reactivity. In this review, the synthesis, structure, reactivity, and application of push–pull ynamines, push–pull ynecarbamates, push–pull ...
Hans‐Joachim Gais
wiley   +1 more source

Design and Synthesis of Lactose‐Derived Ligands and Their Application in Asymmetric Friedel–Crafts Alkylation

European Journal of Organic Chemistry, EarlyView.
This work describes the synthesis of lactose‐ and glucose‐derived chiral ligands and their application in the catalytic enantioselective Friedel–Crafts alkylation of indole with a series of trans‐β‐nitrostyrenes. The optimal ligand was an acetate protected, lactose‐derived pyridyl imine and its zinc complex afforded ees up to 93% and yields up to 93 ...
Sandra Bulawa, Julia Bruno‐Colmenarez, Patrick J. Guiry   +2 more
wiley   +1 more source

Isoquinoline Alkaloids and Indole Alkaloids Attenuate Aortic Atherosclerosis in Apolipoprotein E Deficient Mice: A Systematic Review and Meta-Analysis

Frontiers in Pharmacology, 2018
Background: Several studies have attempted to relate the bioactive alkaloid with atherosclerotic cardiovascular diseases prevention in animal models, providing inconsistent results.
Yibing Zhang, Yibing Zhang, Min Li, Xiangjun Li, Tong Zhang, Meng Qin, Liqun Ren   +6 more
doaj   +1 more source

3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity [PDF]

, 2015
A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized.
Attanzio, A., Barraja, P., Carbone, A., Ciancimino, C., Cirrincione, G., Di Vita, G., Diana, P., Livrea, M., Montalbano, A., Parrino, B., Span\uf2, V., Tesoriere, L.   +11 more
core   +2 more sources

Phase‐Transfer‐Catalyzed Interrupted Barton–Zard Reaction Between Electron‐Deficient Indoles and Benzophenone‐Derived Isocyanides

European Journal of Organic Chemistry, EarlyView.
A cascade reaction under phase‐transfer conditions between 3‐nitro indoles and isocyanomethylene dibenzenes affords the construction of pyrrolo[3,4‐b]indole cores. Control experiments provide insight into moderate product yields and clarify why the reaction is not amenable to asymmetric induction. A cascade reaction enabling the construction of pyrrolo[
Ana Mikleušević, Ines Bašić, Mateja Matišić, Josip Rešetar, Matija Gredičak   +4 more
wiley   +1 more source

Analysis of alkaloids (indole alkaloids, isoquinoline alkaloids, tropane alkaloids)

, 2020
Alkaloids are a large cluster of molecules found in Mother Nature all over the world. They are all secondary compounds and collection of miscellaneous elements and biomolecules, derived from amino acids or from transamination. This diverse chemical group is categorized, based on the amino acids that deliver their nitrogen atom and part of their ...
Dey, Prasanta, Kundu, Amit, Kumar, Anoop, Gupta, Meenakshi, Lee, Byung Mu, Bhakta, Tejendra, Dash, Suvakanta, Kim, Hyung Sik   +7 more
openaire   +1 more source