Results 31 to 40 of about 30,006 (268)

Indole Alkaloids and Chromones from the Stem Bark of Cassia alata and Their Antiviral Activities

Molecules, 2022
The Cassia (Leguminosae) genus has attracted a lot of attention as a prolific source of alkaloids and chromones with diverse structures and biological properties. The aim of this study is to screen the antiviral compounds from Cassia alata.
Pei-Song Yang, Jia-Meng Dai, Xue-Jiao Gu, Wen Xiong, De-Quan Huang, Shi-Yu Qiu, Jun-Na Zheng, Yong Li, Feng-Xian Yang, Min Zhou   +9 more
doaj   +1 more source

Marine Alkaloid 2,2-Bis(6-bromo-3-indolyl) Ethylamine and Its Synthetic Derivatives Inhibit Microbial Biofilms Formation and Disaggregate Developed Biofilms [PDF]

, 2019
The antimicrobial activity of the marine bisindole alkaloid 2,2-bis(6-bromo-3-indolyl) ethylamine (1) and related synthetic analogues (compounds 2–8) against target microorganisms was investigated by Minimum Inhibitory Concentration (MIC) determination ...
Baffone, Wally, Campana, Raffaella, Favi, Gianfranco, Lucarini, Simone   +3 more
core   +1 more source

Crystal structure of 2,3-dimethoxy-5,6,7,8,13,13a-hexahydro-6a,8-diazaindeno[2,1-b]phenanthrene methanol monosolvate

Acta Crystallographica Section E: Crystallographic Communications, 2015
The asymmetric unit of the title solvate, C21H22N2O2·CH3OH, contains one methanol solvent molecule and one molecule of the heterocycle that is built up by the fusion of four six-membered rings A, C, D, E and one five-membered ring B.
Shahobiddin M. Adizov, Abdusalom Sh. Saidov, Kambarali K. Turgunov, Rasul Ya. Okmanov, Bakhodir Tashkhodjaev   +4 more
doaj   +1 more source

Constituents of Medicinal Plants of Lombok: A New Antibacterial Alkaloid from (Bl.) Rolfe

Natural Product Communications, 2006
A new, weakly antibacterial indole alkaloid, named lombine, together with the known alkaloid voacangine, have been isolated from the bark of Voacanga foetida (Bl.) Rolfe (Apocynaceae), a plant used on Lombok, Indonesia, for medicinal purposes. A combined
Surya Hadi, John B. Bremner
doaj   +1 more source

Plant-symbiotic fungi as chemical engineers: multi-genome analysis of the Clavicipitaceae reveals dynamics of alkaloid Loci [PDF]

, 2013
The fungal family Clavicipitaceae includes plant symbionts and parasites that produce several psychoactive and bioprotective alkaloids. The family includes grass symbionts in the epichloae clade (Epichloë and Neotyphodium species), which are ...
A Dereeper, A Krogh, A Leuchtmann, A Markert, A Tanaka, AA Bacetty, AA Salamov, Adrian Leuchtmann, AJ Clutterbuck, AJ Enright, Anar K. Khan, Anna Gordon, Anthony E. Glenn, B Ewing, Barry Scott, Birgitt Oeser, BJ Blaney, BL Cantarel, BL Kutil, Bruce A. Roe, BS Margolin, C Young, C Young, CA Cuomo, CA Young, CA Young, Caroline Machado, Carolyn A. Young, Charles T. Bullock, Christine R. Voisey, Christopher L. Schardl, Chunjie Li, CJ Eaton, CL Schardl, CL Schardl, CL Schardl, CL Schardl, CL Schardl, CM Coyle, D-X Zhang, D-X Zhang, Damien J. Fleetwood, Daniel G. Panaccione, Daniel R. Harris, David C. Haws, DG Panaccione, DG Panaccione, DJ Fleetwood, DJ Fleetwood, Donal M. O'Sullivan, DP Malinowski, E Tanaka, Eckhard Leistner, Eiji Tanaka, Elissaveta G. Arnaoudova, Ella V. Wilson, F Chen, G Mey, GCM Latch, GE Tusnády, GH Sung, H Shimodaira, H Svardal, H-F Tsai, HG Knaus, I Masami, J Jurka, J Tor-Agbidye, J Wang, JA Rudgers, Jan Schmid, Jennifer L. Wiseman, Jennifer S. Webb, Jerzy W. Jaromczyk, JH Bouton, JinGe Liu, Jinze Liu, JL Cenis, Johanna E. Takach, Jolanta Jaromczyk, Joseph Heitman, JR Faulkner, Juan Pan, JW Spatafora, K Clay, K Urga, K Wang, K-R Chung, Kalina Andreeva, Kathryn K. Schweri, Koya Sugawara, KP Schliep, L Li, LD Stein, Li Chen, LJ Iannone, LR Caporael, M Anisimova, M Freitag, M Pava-Ripoll, M Stanke, Mark L. Farman, ME Afkhami, MG Kidwell, Miao Liu, MJ Eadie, MJ Spiering, MJ Spiering, MJ Spiering, MJ Spiering, ML Farman, MM Smith, Murray Cox, N Castagnoli Jr, N Lorenz, N Lorenz, N Lorenz, Neil Moore, Nikki D. Charlton, P Scott, P Tudzynski, Padmaja Nagabhyru, Patrick J. Calie, Paul Tudzynski, PC Lyons, PG Crosignani, PW Ewald, Q Gao, R Chenna, R Edgar, R Jothi, Randy D. Dinkins, RC Edgar, Richard D. Johnson, RJ Cole, RKA Giger, RM Andrie, RT Gallagher, Ruriko Yoshida, RW Thompson, S Guindon, S Huse, S Pažoutová, S Rasmussen, S Saari, S Saikia, S Saikia, S Saikia, S Uhlig, SF Altschul, Simona Florea, SM Li, Stefan G. Amyotte, T Haarmann, T Haarmann, T Philippi, T Rouxel, TH Al-Samarrai, U Steiner, U Steiner, Uljana Hesse, Ulrich Güldener, Ulrike Steiner, V Ter-Hovhannisyan, W Wiesemuller, Wade Mace, Walter Hollin, WM Gao, YY Zhu, Z-q An, Zheng Zeng, Zhiqiang An   +171 more
core   +4 more sources

The ORCA2 transcription factor plays a key role in regulation of the terpenoid indole alkaloid pathway [PDF]

, 2013
Background: The terpenoid indole alkaloid (TIA) pathway leads to the production of pharmaceutically important drugs, such as the anticancer compounds vinblastine and vincristine.
Gibson, Susan, Leopold, Alex, Li, Chun, Sander, Guy, Shanks, Jacqueline, Shanks, Jacqueline, Zhao, Le   +6 more
core   +3 more sources

Plant Genetic Engineering: Technological Pathways, Application Scenarios, and Future Directions

Advanced Science, EarlyView.
This review maps the fast‐evolving landscape of plant genetic engineering, linking enabling platforms with trait‐focused applications in architecture optimization, stress resilience, yield improvement, and quality enhancement. It highlights how genome editing, transgenic strategies, and emerging multi‐gene approaches reshape breeding pipelines, while ...
Peilin Wang, Wenzhi Wang, Dongjiao Wang, Qibin Wu, Youxiong Que   +4 more
wiley   +1 more source

Antibacterial activity of alkaloid extracts from Ochrosia oppositifolia [PDF]

, 2017
Ochrosia oppositifolia can be found along the coastline and is locally known as ‘Mempelam pasih’ or ‘Mangga laut’. In this study, the alkaloids from the leaves, stem-bark and roots were extracted and tested for their antibacterial activity.
Nazlina Ibrahim,, Puteri I.A.M. Mahmud,, W.A. Yaacob,   +2 more
core   +1 more source

Chromosome-level genome assembly of Ophiorrhiza pumila reveals the evolution of camptothecin biosynthesis

Nature Communications, 2021
Ophiorrhiza pumila is a medicinal plant that can produce the anti-cancer monoterpene indole alkaloid (MIA) camptothecin. Here, the authors report its genome assembly and propose a working model for MIA evolution and biosynthesis through comparative ...
Amit Rai, Hideki Hirakawa, Ryo Nakabayashi, Shinji Kikuchi, Koki Hayashi, Megha Rai, Hiroshi Tsugawa, Taiki Nakaya, Tetsuya Mori, Hideki Nagasaki, Runa Fukushi, Yoko Kusuya, Hiroki Takahashi, Hiroshi Uchiyama, Atsushi Toyoda, Shoko Hikosaka, Eiji Goto, Kazuki Saito, Mami Yamazaki   +18 more
doaj   +1 more source

Catalytic enantioselective synthesis of quaternary carbon stereocentres. [PDF]

, 2014
Quaternary carbon stereocentres-carbon atoms to which four distinct carbon substituents are attached-are common features of molecules found in nature. However, before recent advances in chemical catalysis, there were few methods of constructing single ...
Overman, Larry E, Quasdorf, Kyle W
core