Results 61 to 70 of about 30,006 (268)
Food Safety and Health, EarlyView.In this review, we critically summarized the application of natural polysaccharides (NPs) for the treatment of IBD. This approach combines, in a unique way (right), the basic structure–activity relationships of NPs from different origins (left) with their multipronged mode of action, which involves modulation of the gut microbiota and other ...
Felix Danso +3 more
wiley +1 more source
Currencies of Mutualisms: Sources of Alkaloid Genes in Vertically Transmitted Epichloae
Toxins, 2013 The epichloae (Epichloë and Neotyphodium species), a monophyletic group of fungi in the family Clavicipitaceae, are systemic symbionts of cool-season grasses (Poaceae subfamily Poöideae).
Christopher L. Schardl +13 more
doaj +1 more source
ChemistryOpen, 2023 Strictosidine synthase (STR) catalyzes the Pictet–Spengler (PS) reaction of tryptamine and secologanin to produce strictosidine. Recent studies demonstrated that the enzyme can also catalyze the reaction of non‐natural substrates to form new alkaloid ...
Mingqi Mou +5 more
doaj +1 more source
Indole Alkaloids of Ailanthus altissima
Journal of Natural Products, 1984 Ailanthus altissima (Mill.) Swingle, Syn. A. glandulosa Desf. (Simaroubaceae), is a large tree indigenous to China. It is known as the “Tree of Heaven” and has been the subject of several chemical studies. The presence of quassinoid-type bitter principles (1-6), flavonols (7,8), and 2,6-dimethoxy-p-benzoquinone (9,10) has been reported in earlier ...
Souleles, C., Waigh, R.
openaire +2 more sources
Medicinal Research Reviews, EarlyView.ABSTRACT Alzheimer's disease (AD) is a debilitating neurodegenerative condition characterized by progressive cognitive impairment, memory deterioration, and neuronal dysfunction. Its complex pathophysiology involves multiple interlinked processes, including amyloid‐β (Aβ) aggregation, tau hyperphosphorylation, oxidative stress, neuroinflammation ...
Amandeep Thakur +6 more
wiley +1 more source
Memorias do Instituto Oswaldo Cruz, 2013 Infusions of Aspidosperma nitidum (Apocynaceae) wood bark are used to treat fever and malaria in the Amazon Region. Several species of this family are known to possess indole alkaloids and other classes of secondary metabolites, whereas terpenoids, an ...
Julia Penna Coutinho +9 more
doaj +1 more source
Enzyme-catalyzed cationic epoxide rearrangements in quinolone alkaloid biosynthesis. [PDF]
, 2017 Epoxides are highly useful synthons and biosynthons for the construction of complex natural products during total synthesis and biosynthesis, respectively.
Garcia-Borràs, Marc +8 more
core
Trichome Management to Enhance Camptothecins in Camptotheca Decaisne [PDF]
, 2014 Inducible chemical defenses of plants have received much attention in the last three decades, and these defenses often involve trichomes. It is known that some plant secondary metabolites may accumulate in trichomes which can protect plants from damage ...
Li, Shiyou +3 more
core +2 more sources
Proteins: Structure, Function, and Bioinformatics, EarlyView.ABSTRACT BorF is a short‐chain flavin reductase from a desert soil bacterium that uses NADH to reduce FAD to FADH2, which is used by the tryptophan‐6‐halogenase BorH to chlorinate tryptophan in the biosynthetic pathway of borregomycin A. The X‐ray crystal structure of BorF bound to FAD was solved to 2.37 Å by molecular replacement.
Zheng Ma +3 more
wiley +1 more source
Indole Synthesis via Allenyl Ester; Enantioselective Total Synthesis of Geissoschizoline
ChemistryEuropeMethyl indole‐2‐acetate is a key structural motif in plant‐derived indole alkaloids. In this study, a mild and efficient protocol is presented for its preparation using readily available aniline derivatives, which are synthesized from malonic esters. The
Sohsuke Moriue +5 more
doaj +1 more source