Results 141 to 150 of about 149,836 (290)

Synthesis and D2-like binding affinity of new derivatives of N3-[(1- ethyltetrahydro-1H-2-pyrrolyl)methyl]-4,5-dihydrobenzo[g]indole-3- carboxamide and related compounds [PDF]

open access: yes, 2000
In previous papers 4a,b we have reported the syntheses and structure-activity relationships of a series of 5-phenyl-3-pyrrole carboxamide and related 4,5-dihydrobenzo[g]indole-3-carboxamide analogues whose most representative terms were 1a and 2a ...
Chelucci, Giorgio Adolfo   +5 more
core  

Synthesis of pyrrolo[1,2-a]indole-1,8(5H)-diones as new synthons for developing novel tricyclic compounds of pharmaceutical interest [PDF]

open access: yes, 2004
In the course of our work aimed at developing novel heterocycles of pharmaceutical interest, a new tricycle, the tetrahydropyrrolo[1,2-a]indole-1,8-dione, has been synthesized by an intramolecular Friedel-Crafts acylation, as a synthon suitable to be ...
Mura, Alessio   +4 more
core  

Engineered cells for production of indole-derivatives

open access: yes, 2020
Integral membrane proteins capable of transporting melatonin and other indole-derivatives across biological membranes, and uses thereof.
Kell, Douglas, Yang, Lei, Malla, Sailesh
openaire   +1 more source

Ribozymes for RNA‐Catalyzed RNA Methylation and Labeling

open access: yesAngewandte Chemie International Edition, EarlyView.
Ribozymes are powerful tools for site‐specific RNA modification. Their activities range from installing tags and fluorophores to generating natural RNA methylations, making them valuable tools to uncover the many functions that RNA plays in nature.
Carolin P. M. Scheitl   +1 more
wiley   +1 more source

Microbiota-dependent indole production stimulates the development of collagen-induced arthritis in mice

open access: yesThe Journal of Clinical Investigation
Altered tryptophan catabolism has been identified in inflammatory diseases like rheumatoid arthritis (RA) and spondyloarthritis (SpA), but the causal mechanisms linking tryptophan metabolites to disease are unknown.
Brenda J. Seymour   +21 more
doaj   +1 more source

Indol Production of Bacteria [PDF]

open access: yesInternational Bulletin of Bacteriological Nomenclature and Taxonomy, 1952
openaire   +1 more source

Cane molasses as a source of precursors in the bioproduction of tryptophan by Bacillus subtilis

open access: yesIranian Journal of Microbiology, 2013
Background and Objectives: The essential amino acid L-tryptophan can be produced by a condensation reaction between indole and L-serine, catalyzed by B. subtilis with tryptophan synthase activity.
Marzieh Dehghan-Shasaltaneh   +3 more
doaj  

AraC‐Family Transcriptional Regulator WhpR Controls Virulence in Pseudomonas savastanoi pv. savastanoi Through Regulation of Indole Metabolism

open access: yesMicrobial Biotechnology
The Pseudomonas syringae complex WHOP genomic island underpins virulence in woody hosts by mediating the catabolism of aromatic compounds. However, the biochemical functions of the ipoABC and dhoAB operons and the regulatory gene whpR remain unknown ...
Antonio Arroyo‐Mateo   +3 more
doaj   +1 more source

Longitudinal Modulation of the Gut Microbiome and Growth Performance by Phytochemicals as Antibiotic Alternatives in Swine Production

open access: yesAnimal Research and One Health, EarlyView.
We conducted a longitudinal trial across nursery, growing, and finishing phases, showing that phytochemical supplementation as a potential antibiotic alternative reduced potential pathogens and promoted beneficial Lactobacillus amylovorus in the nursery phase, and enriched amino acid and carbohydrate metabolism pathways (prediction) during finishing ...
Ziyu Liu   +11 more
wiley   +1 more source

Gut Health in Ostriches (Struthio camelus): Insights Into Intestinal Structure, Functions, Microbiome, and Improvement Strategies

open access: yesAnimal Research and One Health, EarlyView.
Our paper systematically reviews the intestinal structure, function, and microbiota of ostriches, along with strategies for improving their gut health. We analyze how these factors collectively influence intestinal homeostasis and ostrich welfare, emphasizing probiotics as a promising intervention to enhance gut health, boost population well‐being, and
Zi‐Qun Zhang   +6 more
wiley   +1 more source

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