Results 61 to 70 of about 173,121 (147)

Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: Potential role in maturation of the naive immune system

open access: yes, 2009
Thymic indoleamine 2,3-dioxygenase-positive eosinophils in young children: Potential role in maturation of the naive immune ...
A Charles (7836275)   +10 more
core  

Inhibition of indoleamine 2,3 dioxygenase activity by H2O2

open access: yes, 2006
Indoleamine 2,3-dioxygenase is the first and rate limiting enzyme of the kynurenine pathway of tryptophan metabolism, has potent effects on cell proliferation and mediates antimicrobial, antitumorogenic, and immuno suppressive effects.
Smythe, George A   +17 more
core   +1 more source

Corrigendum: Untargeted metabolomics identified kynurenine as a predictive prognostic biomarker in acute myocardial infarction

open access: yesFrontiers in Immunology, 2023
Xiaolin Zhang   +13 more
doaj   +1 more source

Tryprophan metbolism in alcoholism. Tryptophan but not excitatory amino acid availablity to the brain is increased before the appearance of the alcohol-withdrawal syndrome in men [PDF]

open access: yes, 1998
Tryptophan (Trp) metabolism and disposition and excitatory and other amino acid concentrations were determined in alcohol-dependent subjects in relation to the alcohol-withdrawal syndrome (AWS).
Morgan, Christopher J.   +7 more
core  

Substrate Inhibition in Human Indoleamine 2,3-Dioxygenase

open access: yes, 2015
Human indoleamine 2,3-dioxygenase (hIDO) catalyzes the oxidative cleavage of the L-tryptophan (l-Trp) pyrrole ring. Catalysis is inhibited at high substrate concentrations; mechanistic details of this observation are, however, still under debate.
Elena Nickel (1308744)   +4 more
core   +1 more source

High INDO (indoleamine 2,3-dioxygenase) mRNA level in blasts of acute myeloid leukemic patients predicts poor clinical outcome [PDF]

open access: yes, 2008
Indoleamine 2,3-dioxygenase degrades the amino acid tryptophan which is essential for T cells. Tryptophan depletion causes T-cell cycle arrest and solid tumors that express high levels of indoleamine 2,3-dioxygenase can create immune suppression ...
Chamuleau, M.E.D. (Martine)   +8 more
core   +1 more source

Oral tolerance induction in indoleamine 2,3-dioxygenase-expressing CD11cdendritic cells of tolerized mice

open access: yes, 2011
The induction of oral tolerance increases the proportion of indoleamine 2,3-dioxygenase (IDO)-expressing CD11cdendritic cells (DCs) in Peyer's patches of tolerized mice.
Young-Ok Jung (46883)   +11 more
core   +1 more source

Characterization and Nonenzymatic Transformation of Three Types of Alkaloids from Streptomyces albogriseolus MGR072 and Discovery of Inhibitors of Indoleamine 2,3-Dioxygenase

open access: yes, 2019
The known benzonaphthyridine alkaloid, albogrisin A (1), and six new compounds, including two pyrazinone stereoisomers, albogrisin B (2)/B′ (2′), together with four 4H-pyrroloquinolinones, two diastereoisomers, albogrisin C (3)/C′ (3′), and their methyl ...
Du Gao (748330)   +7 more
core   +1 more source

Indoleamine 2,3-dioxygenase expression and overall survival in patients diagnosed with breast cancer in Pakistan

open access: yes, 2019
Kashif Asghar,1 Asif Loya,2 Iftikhar Ali Rana,2 Muhammad Tahseen,2 Muhammad Ishaq,2 Asim Farooq,3 Muhammad Abu Bakar,4 Iqra Masood5 1Department of Basic Sciences, Shaukat Khanum Memorial Cancer Hospital and Research Centre (SKMCH & RC), Lahore ...
Ishaq M   +7 more
core  

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