Results 31 to 40 of about 3,209 (136)

Dual metabolism-disrupted nanoparticles for reprogramming the immune microenvironment to potentiate cuproptosis immunotherapy

Materials Today Bio
Reprogramming the metabolism-mediated tumor microenvironment is a promising strategy to revitalize antitumor immunity. However, single metabolic modulation is often insufficient to achieve significant antitumor effects due to the intricate metabolic ...
Songyan Li, Zilin Ma, Yilei Zhao, Jie Yan, Xuechun Wang, Wen Zhao, Jianwei Jiao, Xiuying Duan, Guiqiang Zhang   +8 more
doaj   +1 more source

A latent ability to persist: differentiation in Toxoplasma gondii [PDF]

, 2018
A critical factor in the transmission and pathogenesis of Toxoplasma gondii is the ability to convert from an acute disease-causing, proliferative stage (tachyzoite), to a chronic, dormant stage (bradyzoite).
Jeffers, Victoria, Kim, Kami, Sullivan, William J., Jr., Tampaki, Zoi   +3 more
core   +1 more source

DPSCs from Inflamed Pulp Modulate Macrophage Function via the TNF-α/IDO Axis [PDF]

, 2016
Human dental pulp stem cells (DPSCs) can be isolated from inflamed pulp derived from carious teeth with symptomatic irreversible pulpitis (I-DPSCs), which possess stemness and multidifferentiation potentials similar to DPSCs from healthy pulp.
Karabucak, B, Le, A D, Lee, S, Zhang, Q Z   +3 more
core   +2 more sources

Effect of Cell Seeding Density and Inflammatory Cytokines on Adipose Tissue-Derived Stem Cells: an in Vitro Study [PDF]

, 2017
Adipose tissue-derived stem cells (ASCs) are known to be able to promote repair of injured tissue via paracrine factors. However, the effect of cell density and inflammatory cytokines on the paracrine ability of ASCs remains largely unknown.
Bastiaansen-Jenniskens, Y.M. (Yvonne), Hesselink, J.W. (Jan Willem), Kirpensteijn, J. (Jolle), Osch, G.J.V.M. (Gerjo) van, Sukho, P. (Panithi), Verseijden, F. (Femke)   +5 more
core   +1 more source

Lactobacillus Johnsonii YH1136 alleviates schizophrenia-like behavior in mice: a gut–microbiota–brain axis hypothesis study

BMC Microbiology
Based on the microbiota–gut–brain axis (MGBA) hypothesis, probiotics play an increasingly important role in treating various psychiatric disorders. Schizophrenia (SCZ) is a common mental disease with a complex pathogenesis and is challenging to treat ...
Liqin Zheng, Jinge Xin, Huiqian Ye, Ning Sun, Baoxing Gan, Xuemei Gong, Shusheng Bao, Min Xiang, Hesong Wang, Xueqin Ni, Hao Li, Tao Zhang   +11 more
doaj   +1 more source

Pathways and molecules for overcoming immunotolerance in metastatic gastrointestinal tumors

Frontiers in Immunology
Worldwide, gastrointestinal (GI) cancer is recognized as one of the leading malignancies diagnosed in both genders, with mortality largely attributed to metastatic dissemination.
Qixin Gan, Yue Li, Yuejun Li, Haifen Liu, Daochuan Chen, Lanxiang Liu, Churan Peng   +6 more
doaj   +1 more source

Irradiation to Improve the Response to Immunotherapeutic Agents in Glioblastomas. [PDF]

, 2019
PurposeGlioblastoma (GBM) remains an incurable disease despite extensive treatment with surgical resection, irradiation, and temozolomide. In line with many other forms of aggressive cancers, GBM is currently under consideration as a target for ...
Kaprealian, Tania, Lee, Mi-Heon, McBride, William H, Nesseler, Jean Philippe, Nickers, Philippe, Niclou, Simone P, Schaue, Dorthe   +6 more
core  

Tumoricidal efficacy coincides with CD11c up-regulation in antigen-specific CD8+ T cells during vaccine immunotherapy [PDF]

, 2016
Background: Dendritic cells (DCs) mount tumor-associated antigens (TAAs), and the double-stranded RNA adjuvant Poly(I:C) stimulates Toll-like receptor 3 (TLR3) signal in DC, which in turn induces type I interferon (IFN) and interleukin-12 (IL-12), then ...
A Driessche Van, AM Eggermont, BK Choi, BL Myones, D Fujiwara, DS Vinay, DS Vinay, E Yefenof, EM Shevach, J Crespo, JJ Obar, JM Chinai, JP Metlay, JW Huleatt, K Franciszkiewicz, LS Schlesinger, M Aldarouish, M Azuma, M Matsumoto, M Matsumoto, M Sznol, Masahiro Azuma, Misako Matsumoto, OP Joffre, PG Coulie, SA Ju, SA Rosenberg, T Seya, T Seya, T Seya, Tsukasa Seya, Y Lin, Yohei Takeda   +32 more
core   +5 more sources

Mesenchymal stem cells and immunomodulation: current status and future prospects [PDF]

, 2016
published_or_final_versio
CHEN, L, Chiu, SM, Fu, QINF-LING, GAO, F, Ji, HONG-LIN, Lian, Q, Motan, DAL, Tse, HF, ZHANG, Z   +8 more
core   +1 more source

Tissue Engineering and Regenerative Medicine: Perspectives and Challenges

MedComm, Volume 6, Issue 5, May 2025.
Tissue engineering and regenerative medicine. This review presents cell therapy, extracellular vesicle therapy, and tissue engineering in regenerative medicine, highlighting their key historical milestones, clinical applications, and current challenges.
Van T. Hoang, Quyen Thi Nguyen, Trang Thi Kieu Phan, Trang H. Pham, Nhung Thi Hong Dinh, Le Phuong Hoang Anh, Lan Thi Mai Dao, Van Dat Bui, Hong‐Nhung Dao, Duc Son Le, Anh Thi Lan Ngo, Quang‐Duong Le, Liem Nguyen Thanh   +12 more
wiley   +1 more source