Results 31 to 40 of about 18,349 (196)

IDO1 (indoleamine 2,3-dioxygenase 1) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on IDO1 (indoleamine 2,3-dioxygenase 1), with data on DNA, on the protein encoded, and where the gene is implicated.
Chang, MY, Muller, AJ, Prendergast, GC
openaire   +2 more sources

Vitamin e-loaded membrane dialyzers reduce hemodialysis inflammaging

BMC Nephrology, 2019
Background Inflammaging is a persistent, low−grade, sterile, nonresolving inflammatory state, associated with the senescence of the immune system. Such condition downregulates both innate and adaptive immune responses during chronic disorders as type II ...
Vincenzo Sepe, Marilena Gregorini, Teresa Rampino, Pasquale Esposito, Rosanna Coppo, Francesco Galli, Carmelo Libetta   +6 more
doaj   +1 more source

Chronic lymphocytic leukemia nurse-like cells express hepatocyte growth factor receptor (c-MET) and indoleamine 2,3-dioxygenase and display features of immunosuppressive type 2 skewed macrophages

Haematologica, 2014
Hepatocyte growth factor, produced by stromal and follicular dendritic cells, and present at high concentrations in the sera of patients with chronic lymphocytic leukemia, prolongs the survival of leukemic B cells by interacting with their receptor, c ...
Paolo Giannoni, Gabriella Pietra, Giorgia Travaini, Rodolfo Quarto, Genti Shyti, Roberto Benelli, Laura Ottaggio, Maria Cristina Mingari, Simona Zupo, Giovanna Cutrona, Ivana Pierri, Enrico Balleari, Alessandra Pattarozzi, Marco Calvaruso, Claudio Tripodo, Manlio Ferrarini, Daniela de Totero   +16 more
doaj   +1 more source

Enhanced Immunomodulation in Inflammatory Environments Favors Human Cardiac Mesenchymal Stromal-Like Cells for Allogeneic Cell Therapies [PDF]

, 2019
Rising numbers of patients with cardiovascular diseases and limited availability of donor hearts require new and improved therapy strategies. Human atrial appendage-derived cells (hAACs) are promising candidates for an allogeneic cell-based treatment. In
Diedrichs, Falk, Haag, Marion, Jürchott, Karsten, Seifert, Martina, Sittinger, Michael, Stolk, Meaghan   +5 more
core   +1 more source

IDO2 (indoleamine 2,3-dioxygenase 2) [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
Review on IDO2 (indoleamine 2,3-dioxygenase 2), with data on DNA, on the protein encoded, and where the gene is implicated.
Chang, MY, Metz, R, Muller, AJ, Prendergast, GC   +3 more
openaire   +2 more sources

Indoleamine 2,3-dioxygenase (IDO): Only an enzyme or a checkpoint controller?

Journal of Oncological Sciences, 2017
Tryptophan (Trp) is one of the important essential amino acids and Kynurenine pathway (KP) is the first and rate limiting step of degrading Trp to active metabolites.
Cemil Bilir, M.D., Can Sarisozen, PhD
doaj   +1 more source

The role of immune homeostasis in patients with new coronavirus infection (COVID-19) in the development of invasive pulmonary aspergillosis

Журнал инфектологии, 2023
Recently, more attention has been paid to the role of indolamine-2,3-dioxygenase and aryl hydrocarbon receptor in maintaining a balance between immune reactivity and tolerance in various infectious diseases.
A. E. Taraskina, E. V. Frolova, O. V. Shadrivova, O. V. Sekretareva, N. V. Vasilyeva   +4 more
doaj   +1 more source

Effects of upregulated indoleamine 2, 3-dioxygenase 1 by interferon γ gene transfer on interferon γ-mediated antitumor activity. [PDF]

, 2014
Interferon γ (IFN-γ), an anticancer agent, is a strong inducer of indoleamine 2, 3-dioxygenase 1 (IDO1), which is a tryptophan-metabolizing enzyme involved in the induction of tumor immune tolerance.
Ando, M, Nishikawa, M, Saito, K, Takahashi, Y, Takakura, Y, Watanabe, Y, Watcharanurak, K, Yamamoto, Y, Yoshinaga, K, Zang, L   +9 more
core   +1 more source

Engineering Osteoimmune Responses with Functionalized Orthopedic Implants for Post‐Operative Osteosarcoma Treatment

Advanced Science, EarlyView.
Osteosarcoma is the most common primary bone tumor with limited treatment options and a terrible prognosis. This review provides a comprehensive summary of the recent development of osteoimmunomodulatory implants for post‐operative osteosarcoma treatment, of which the potential utility in evoking durable anti‐osteosarcoma immunity and accelerating bone
Yilong Dong, Lingshuang Wang, Hui Zhang, Menghuan Li, Zhong Luo, Yan Hu, Chunyuan Cai   +6 more
wiley   +1 more source

Genetic deficiency of indoleamine 2,3-dioxygenase promotes gut microbiota-mediated metabolic health. [PDF]

, 2018
The association between altered gut microbiota, intestinal permeability, inflammation and cardiometabolic diseases is becoming increasingly clear but remains poorly understood1,2.
Alzaid, Fawaz, Burcelin, Remy, Callebert, Jacques, Cardellini, Marina, Chajadine, Mouna, Dairou, Julien, Denis, Raphael GP, Esposito, Bruno, Federici, Massimo, Fernandez-Real, José Manuel, Haddad, Yacine, Jegou, Sarah, Launay, Jean-Marie, Laurans, Ludivine, Luquet, Serge H, Mallat, Ziad, McQuitty, Claire, Metghalchi, Sarvenaz, Moreno-Navarrete, Jose-Maria, Sokol, Harry, Sovran, Bruno, Straub, Marjolene, Taleb, Soraya, Tavitian, Bertrand, Tedgui, Alain, Venteclef, Nicolas, Viel, Thomas   +26 more
core   +2 more sources