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Human Indoleamine 2,3-Dioxygenase 1 Is an Efficient Mammalian Nitrite Reductase

Biochemistry, 2018
The heme enzyme indoleamine 2,3-dioxygenase-1 (IDO1) catalyzes the first reaction of l-tryptophan oxidation along the kynurenine pathway. IDO1 is a central immunoregulatory enzyme with important implications for inflammation, infectious disease, autoimmune disorders, and cancer.
Yean J. Lim   +9 more
openaire   +3 more sources

Reliable detection of indoleamine 2,3 dioxygenase-1 in murine cells and tissues

2019
The essential amino acid tryptophan is catabolized by the first and rate-limiting enzyme of the kynurenine pathway, indoleamine 2,3-dioxygenase-1 (IDO1). IDO1 is implicated in several diseases including cancer, chronic infection, autoimmune disorders and neurodegenerative diseases.
Sunil, Thomas   +2 more
openaire   +2 more sources

Indoleamine 2,3-dioxygenase (IDO) inhibitors and cancer immunotherapy

Cancer Treatment Reviews, 2022
Sarabjot Pabla   +2 more
exaly  

Indoleamine 2,3‐dioxygenase 1 (IDO1): an up‐to‐date overview of an eclectic immunoregulatory enzyme

FEBS Journal, 2022
Ursula Grohmann   +2 more
exaly  

The Role of Indoleamine 2, 3-Dioxygenase in Immune Suppression and Autoimmunity

Vaccines, 2015
Jacques Christian Mbongue   +2 more
exaly  

Studies on Tissue and Cellular Distribution of Indoleamine 2,3-Dioxygenase 2

Journal of Histochemistry and Cytochemistry, 2012
Masato Hoshi, Yasuko Yamamoto
exaly  

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