Results 101 to 110 of about 45,952 (286)

Unlocking Long‐Lived Charge‐Separated State in Pentamethine Cyanine Based on Anionic Hofmeister Effect for Photodynamic Immunotherapy

open access: yesAdvanced Science, EarlyView.
Based on the anionic Hofmeister effect, a universal strategy of incorporation of stereo‐π anion BPh4− into a series of Cy5 skeletons to unlock long‐lived charge‐separated states was reported, wherein the weak electronic coupling and low charge recombination driving force hinder the charge recombination process, elevating the oxygen‐independent ROS ...
Xuan Zhao   +9 more
wiley   +1 more source

(1H-Benzo[d][1,2,3]triazol-1-yl)(5-bromo-1-hydroxy-1H-indol-3-yl)methanone

open access: yesMolbank, 2014
The title compound was easily prepared by a nitrosoarene-alkyne cycloaddition reaction carried out in toluene at 80 °C. The product is a highly functionalized compound that can be further derivatized through various functional group interconversion ...
Francesco Tibiletti   +5 more
doaj   +1 more source

The Neber Route to Substituted Indoles

open access: yes, 2016
Two complementary procedures have been developed for the conversion of the oximes of α-aryl ketones to azirines. On heating, the azirines rearrange smoothly to the corresponding indoles.
Weiwei Tian (1903132)   +1 more
core   +1 more source

Gut Microbiota‐Derived Indole‐3‐Propionic Acid Alleviates Diabetic Osteoporosis Through Nrf2‐Mediated Ferroptosis Suppression

open access: yesAdvanced Science, EarlyView.
Diabetes‐associated dysbiosis is accompanied by reduced Clostridium abundance, impaired microbial tryptophan metabolism, and lower circulating indole‐3‐propionic acid (IPA). Exogenous IPA improves trabecular microarchitecture and bone formation and restores Nrf2‐associated antioxidant signaling in bone marrow mesenchymal stem cells, limiting iron ...
Jinwu Bai   +12 more
wiley   +1 more source

Solventless clay-promoted Friedel-Crafts reaction of indoles with alpha-amido sulfones: Unexpected synthesis of 3-(1-arylsulfonylalkyl) indoles

open access: yes, 2006
Friedel-Crafts reaction of indoles with r-amido sulfones in the presence of montmorillonite K-10 leads unexpectedly to 3-(1-arylsulfonylalkyl)indoles in good yield.
PETRINI, Marino   +3 more
core   +1 more source

An Efficient Route to 2,3-Disubstituted Indoles via Reductive Alkylation Using H2 as Reductant

open access: yes, 2011
An Efficient Route to 2,3-Disubstituted Indoles via Reductive Alkylation Using H2 as ...
曹亮亮   +3 more
core  

ROS‐Responsive Nanoparticle Delivery of Dexmedetomidine Protects the Gut Vascular Barrier After Intestinal Ischemia/Reperfusion via the HDAC‐H3K27ac‐TCF4 Axis

open access: yesAdvanced Science, EarlyView.
A low dose of dexmedetomidine, delivered by ROS‐responsive nanoparticles, preferentially accumulates in the ischemic intestine and restores gut vascular barrier integrity after ischemia/reperfusion injury. This nanoparticle‐based strategy prevents bacterial translocation and liver damage without cardiorespiratory side effects, working through HDAC ...
Hu‐Fei Zhang   +10 more
wiley   +1 more source

Radical intermediates in the peroxidation of indoles

open access: yes, 2001
2-Substituted and 1,2-disubstituted indoles react with m-chloroperbenzoic acid and hydrogen peroxide in the presence of acid or calcium chloride affording 2- and 3-(3-oxoindol-2-yl)indoles; whereas 2,3-disubstituted indoles, reacting with the same ...
P. ASTOLFI   +10 more
core   +1 more source

Photocatalytic Alkylation of Pyrroles and Indoles with α-Diazo Esters [PDF]

open access: yes, 2019
This article describes direct photoalkylation of electron-rich aromatic compounds with diazo compoiunds. C-2 alkylated indoles and pyrroles are obtained with good yields even though the photocatalyst (Ru(bpy)3Cl2) loading is as low as 0.075 mol %.
Jakub, Durka   +2 more
core   +1 more source

Ammonification Process Is Limited by Transformation of Medium Molecular Weight Nitrogenous Organics but Not Hydrolysis of Proteins

open access: yesAdvanced Science, EarlyView.
A multi‐level analytical framework, integrating protein‐level persistence analysis, nontargeted HRMS formula tracking, peptide‐level proteomics, and targeted monomer quantification under varying redox conditions, together with FMO calculations reveal that ammonification is limited by medium molecular weight nitrogenous multimers.
Jing Li   +4 more
wiley   +1 more source

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