Results 101 to 110 of about 44,366 (284)

Comparaison des qualités sensorielles de la viande et de la carcasse d’agneaux élevés au pâturage en production biologique ou conventionnelle à deux niveaux de disponibilités en herbe [PDF]

, 2012
Nous avons comparé les qualités sensorielles des carcasses et des viandes d’agneaux engraissés au pâturage en élevage biologique ou conventionnel (O vs. C) à deux niveaux de disponibilités en herbe (Haut H vs. Bas L).
Prache, S., Guy, F., Ballet, J., Meteau, K., Vannier, E., Musset, M.A.   +5 more
core  

Soft Hypoxia‐Adaptive Bioelectronics Integrating PEDOT:PSS/Polydopamine/Enzyme Biocomposites for Closed‐Loop Therapeutics of Chronic Wounds

Advanced Science, EarlyView.
Hypoxia‐adaptive bioelectronics based on poly(3,4‐ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS)/polydopamine (PDA)/enzyme biocomposites couple O2‐centric biosensing with embedded O2 therapy to address oxygen‐deficient chronic wounds. Local O2 provision restores enzyme‐based metabolite sensing, while catalase‐mediated oxygen generation and
Songrui Liu, Bowen Yang, Cao Qi, Zhijie Zhou, Haochen Zou, Anjum Qureshi, Xiao Zhao, Ting Li, Li Gao, Ye Tao, Gang Song, Pingqiang Cai, Zheng Li, Zhiyuan Liu, Dianpeng Qi, Ting Wang, Lianhui Wang   +16 more
wiley   +1 more source

Copper(II)-Catalyzed Direct C3 Chalcogenylation of Indoles

Molecules
3-Chalcogenylindoles serve as crucial building blocks in organic synthesis and pharmaceutical chemistry. Herein, we describe a simple and general synthesis of 3-chalcogenylindoles through the direct C–H chalcogenation of indoles using N-selenophthalimide
Liuyan Pan, Shengwei Chen, Dongfang Wu, Jian Shao, Xiaofeng Bao, Gong-Qing Liu   +5 more
doaj   +1 more source

Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy

Advanced Science, EarlyView.
By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng, Lei Zheng, Rongkun Tao, Sirui Zheng, Yanke Zhong, Yongxia Niu, Peng Zhang, Xiang Ma, Chen Yang, Min Zhang, Fuyu Duan, Jing Yang, Xuan Wei, Xiang Zhou, Zhenbiao Yang, Zhaoxi Sun, Qizhou Lian   +16 more
wiley   +1 more source

Palladium-Catalyzed Synthesis of 3‑Acylated Indoles Involving Oxidative Cross-Coupling of Indoles with α‑Amino Carbonyl Compounds

, 2016
A new and selective C–N bond oxidative cleavage method to 3-acylated indoles by Pd-catalyzed oxidative cross coupling of indoles with α-amino carbonyl compounds has been developed; moreover, one-pot synthesis of 3-acylated indoles from 2-ethynylanilines ...
Ri-Yuan Tang (546362), Jin-Heng Li (1457626), Jian-Nan Xiang (1856548), Xiao-Kang Guo (1883434)   +3 more
core   +2 more sources

Deproto-metallation of N-arylated pyrroles and indoles using a mixed lithium–zinc base and regioselectivity-computed CH acidity relationship

Beilstein Journal of Organic Chemistry, 2015
The synthesis of N-arylated pyrroles and indoles is documented, as well as their functionalization by deprotonative metallation using the base in situ prepared from LiTMP and ZnCl2·TMEDA (1/3 equiv).
Mohamed Yacine Ameur Messaoud, Ghenia Bentabed-Ababsa, Madani Hedidi, Aïcha Derdour, Floris Chevallier, Yury S. Halauko, Oleg A. Ivashkevich, Vadim E. Matulis, Laurent Picot, Valérie Thiéry, Thierry Roisnel, Vincent Dorcet, Florence Mongin   +12 more
doaj   +1 more source

Cobalt‐Catalyzed Asymmetric Construction of Boron Stereocenters With C–N Axial Chirality

Advanced Science, EarlyView.
A cobalt/Salox‐catalyzed one‐pot annulation enables enantioselective formation of B‐stereogenic centers and C─N axial chirality via C─H/N─H annulation, affording diverse fluorescent products with high stereocontrol and optoelectronic potential. ABSTRACT The efficient construction of boron stereogenic centers alongside axial chirality remains a ...
Subramani Kumaran, Harihara Subramanian Ravi Sankar, Pritam Maity, J. Richard Premkumar, Abir Das, Basker Sundararaju   +5 more
wiley   +1 more source

Aminofluorination of 2-alkynylanilines: a Au-catalyzed entry to fluorinated indoles

Beilstein Journal of Organic Chemistry, 2014
The scope and limitations of gold-catalyzed tandem cycloisomerization/fluorination reactions of unprotected 2-alkynylanilines to have access to 3,3-difluoro-2-aryl-3H-indoles and 3-fluoro-2-arylindoles are described.
Antonio Arcadi, Emanuela Pietropaolo, Antonello Alvino, Véronique Michelet   +3 more
doaj   +1 more source

Dehydration triggered asymmetric hydrogenation of 3-(a-hydroxyalkyl)indoles.

, 2011
Dehydration triggered asymmetric hydrogenation of 3-(a-hydroxyalkyl ...
段英, 江国防, 唐杰, 余长斌, 王躲生, 陈木旺, 周永贵   +6 more
core  

Biochemically Constrained Multi‐Omics Integration Reveals Protein–Metabolite Dependencies Across Diseases

Advanced Science, EarlyView.
ProMetNet introduces a biologically constrained deep learning framework for proteo‐metabolomic integration by embedding Reactome‐derived pathway topology into neural networks. It captures non‐linear molecular dependencies and pathway‐level metabolic reorganization, enabling interpretable discrimination.
Minghui Zhao, Na Zhou, Ruotong Liu, Xiaofei Li, Jian Li, Fuzhong Xue, Qingzhen Hou   +6 more
wiley   +1 more source