Results 131 to 140 of about 27,606 (220)

Reductive rearrangement of substituted quinolines to 2,3-disubstituted indoles enabled by water activation. [PDF]

Chem Sci
Spreckelmeyer N, Kim J, Lammert J, Horst ES, Zhang J, Studer A.   +5 more
europepmc   +1 more source

Protective Effects of Potential Probiotic Pediococcus acidilactici 100 Against Multi‐Drug‐Resistant Diarrheal Escherichia coli Strains Induced Changes in Caenorhabditis elegans Model System

Food Safety and Health, EarlyView.
This study shows the protective effects of potential probiotic strain of Pediococci strains against diarrheal Escherichia coli strains in Caenorhabditis elegans model system. The E. coli strains resulted in severe morphological and physiological damage to the worm whereas the probiotic interventions were able to reduce these damages.
Gunjan Sadera, Anjali Jaglan, Lappasi Mohanram VenkataKrishna, Krishnaswamy Balamurugan, Gunjan Goel   +4 more
wiley   +1 more source

Copper-catalyzed atroposelective hydroarylation of 1-alkynylindoles. [PDF]

Nat Commun
Xu HJ, Chen CM, Zhang Z, Ye LW, Zhou B.
europepmc   +1 more source

Characterization of the Antioxidant Peptides Prepared From the Seed Kernel of Xanthoceras sorbifolium Using Enzymatic Hydrolysis: Molecular Docking Analysis and In Vitro Binding Studies

Food Safety and Health, EarlyView.
XSPH‐I exhibits excellent cellular antioxidant activity and cell protective effects. Four novel antioxidant peptides were screened from XSPH‐I peptide, and the newly synthetic peptide exhibits excellent antioxidant properties in vitro. ABSTRACT In this study, the antioxidant peptides (XSPH) from Xanthoceras sorbifolium oleifera were extracted and ...
Yalin Li, Chao Liu, Rong Sun, Jinyue Sun, Ye Shi, Shihai Lu, Dahu Zhang, Jinwei Qi, Xu Guo, Zhenlin Han, Ningyang Li   +10 more
wiley   +1 more source

Multi-Halogenated Indoles as Antimicrobial and Antivirulence Agents Against Drug-Resistant Staphylococcus aureus. [PDF]

Microb Biotechnol
Sim M, Boya BR, Kim YG, Lee JH, Lee J.
europepmc   +1 more source

Construction of Chronic Kidney Disease Mouse Model Induced by Diets With Different Adenine Content

Food Safety and Health, EarlyView.
By administering a 4 weeks adenine diet to C57BL/6J mice, we identified 0.2% adenine in purified feed as the optimal chronic kidney disease model. This model induces severe renal damage, gut dysbiosis, uremic toxin accumulation, and CKD mineral bone disorder, providing a clinically relevant platform for mechanistic and therapeutic studies.
Wanjun Liao, Jiayao Wang, Yilian Huang, Na Zhang, Xiaodan Shi, Zongcai Tu, Zuohua Xie, Tao Yuan, Hongmei Yin   +8 more
wiley   +1 more source

Antifungal Activities of Multi-Halogenated Indoles Against Drug-Resistant <i>Candida</i> Species. [PDF]

Int J Mol Sci
Jeong H, Boya BR, Kim YG, Lee JH, Lee J.
europepmc   +1 more source

Urolithin A, a Diet‐Derived Gut Microbial Metabolite Against Pulmonary Hypertension Identified via Molecular Docking, Molecular Dynamics and Surface Plasmon Resonance

Food Safety and Health, EarlyView.
Urolithin A, a gut microbial metabolite, binds TNF to suppress proliferation, inflammation, and oxidative stress, offering a promising microbe‐derived therapeutic avenue for pulmonary hypertension. ABSTRACT Pulmonary hypertension (PH) is a complex and multifactorial disease that poses a significant clinical challenge.
Yujie Qu, Yinghua Huo, Yichen Wang, Yao Mu, Xue Yu, Leiyu Tian, Jian Guo, Xuezhi Yang, Yucai Chen   +8 more
wiley   +1 more source

Benzophenone Oxime Tosylate as the Photoacid Generator for the Friedel-Crafts Arylation of Aldehydes With Indoles. [PDF]

Chemistry
Gkosios M, Papatasou P, Antonaki AM, Gkizis PL.   +3 more
europepmc   +1 more source

Interkingdom Interactions in the Gut: Ecological Mechanisms, Homeostasis, and Therapeutic Modulation

Gut Medicine, EarlyView.
ABSTRACT The gut microbiota constitutes a highly complex and dynamic ecosystem that profoundly influences host physiology, metabolism, and immunity. This review provides an integrative overview of the mechanisms through which gut microorganisms—particularly bacteria and fungi—interact with host cells and with each other to maintain intestinal ...
Rui‐Qi Wei, Xin‐Wei Sun, Hao‐Jie Huang, Yu‐Zhi Zhao, Shuang‐Jiang Liu, Chang Liu   +5 more
wiley   +1 more source