Results 141 to 150 of about 45,952 (286)

Synthesis of new N-Benzoxazole and N-Benzothiazole derivatives of 3-(4-Substituted- phenyl)aminoisoxazol-5(2H)-ones and comparison of their base induced rearrangement

Journal of the Brazilian Chemical Society, 2006
3-Arylaminoisoxazol-5(2H)-ones, substituted on nitrogen with benzoxazole and benzothiazole groups react with triethylamine in ethanol under reflux to afford the corresponding indole and imidazobenzothiazole derivatives, respectively.
Khalafy Jabbar, Marjani Ahmad Poursattar, Ebrahimlo Ali Reza Molla   +2 more
doaj  

Correction to “Gut Parabacteroides distasonis‐Derived Indole‐3‐Acetic Acid Promotes Phospholipid Remodeling and Enhances Ferroptosis Sensitivity via the AhR‒FASN Axis in Bladder Cancer”

Advanced Science, EarlyView.
wiley   +1 more source

Atroposelektiver Zugang zu Bizyklischen Peptiden Durch Eine Amid‐Photocaging‐Strategie

Angewandte Chemie, EarlyView.
Ansamere sind eine atypische Klasse von Atropisomeren (Pansa/Mansa) deren stereoselektive Synthese ihrer beiden Konformationsisomere anspruchsvoll ist. Wir stellen eine Strategie mit photogeschützten Amiden vor: Photolabile Gruppen in Monozyklen modulieren reversibel die Amidgeometrie und lenken die Macrolaktamisierung selektiv zu Pansa oder Mansa ...
Haijian Yang, Joseph De Luna, Hui Pan, Jiyong Park, Wu Su, Mu‐Hyun Baik, Roderich D. Süssmuth, Guiyang Yao   +7 more
wiley   +1 more source

Cobalt‐Catalyzed [2σ+2π] Cycloaddition via Site‐Selective Capture of Bicyclobutane Diradical

Angewandte Chemie, EarlyView.
We report a Co(II)‐catalyzed strategy that combines thermal activation of bicyclo[1.1.0]butane (BCBs) with site‐selective radical capture to furnish head‐to‐head fused bicyclo[2.1.1]hexanes via [2σ+2π] cycloaddition with indoles. Detailed mechanistic studies (31P NMR, EPR, CV, and DFT) support the catalytic pathway, while phosphine‐oxide trapping and X‐
Tanmayee Nanda, Alexander Umanzor, Julia Gartzke, Jeremy T. Maddigan‐Wyatt, Philipp Thielert, Stefan Weber, Sabine Richert, Shuming Chen, Daniel B. Werz   +8 more
wiley   +2 more sources

β‐C(sp3)—H Arylierung Aliphatischer Sulfonamide

Angewandte Chemie, EarlyView.
Das erste Protokoll zur β‐C(sp3)—H‐Aktivierung/Funktionalisierung aliphatischer Sulfonamide wird beschrieben. Die Arylierung solcher Substrate wird durch den Einsatz von N‐Acetylthioether‐Liganden ermöglicht und zeichnet sich durch ein breites Substratspektrum sowohl hinsichtlich des Sulfonamid‐Substrats als auch des Arylierungsreagenzes aus.
Friedrich Jurk, Isaac G. Sonsona, Manuel van Gemmeren   +2 more
wiley   +1 more source

Conformation‐Selective Binding Domains of Intramolecular Chemically Induced Protein Dimerisation Systems

Angewandte Chemie, EarlyView.
Intramolecular chemically induced dimerisation transforms FK506‐ and cyclosporine A‐responsive protein pairs into high‐affinity pseudo‐allosteric switches. Holo‐selective binders isolated by mRNA display convert these switches into gain‐of‐signal biosensors and ultrasensitive ELISAs, enabling direct quantification of both immunosuppressants in ...
Zhenling Cui, Zhong Guo, Yi Jin Liew, Alessandro T. Caputo, Maria M. Fiorito, Cagla Ergun Ayva, Roxane Mutschler, Mayra Barrios Leguarca, Sophia Newton, Gia Nghi Lam, Robert Speight, Brett McWhinney, Yanulla Essie Georges, Carel Pretorius, Jacobus P.J. Ungerer, Kirill Alexandrov   +15 more
wiley   +2 more sources

Augmented indoles

ARKIVOC, 2006
David StC. Black, Michelle F. Channon, Kylie A. Clayton, Glenn C. Condie, Jason B. Harper, Naresh Kumar, Karin Pchalek, Tutik Dwi Wahyuningsih   +7 more
doaj   +1 more source

Synthesis of some new 1,2,3-selenadiazolo[4',5':5,4]cyclopent[b]indoles and 6,11-dihydro-5-methylquinolino[2',3 ':5,4]cyclopent [b]indoles

, 2004
2231-2234Reaction of 1-oxo-1,2,3,8-tetrahydrocyclopent[b]indoles 1a-e with semicarbazide hydrochloride produced 1-semicarbazono-1,2,3,8-tetrahydrocyclopent[b]indoles 2a-e, which are subjected to oxidative cyclisation using seleniumdioxide to afford ...
Sangeetha, V, Prasad, K J Rajendra
core  

Synthesis of Large‐ and Medium‐Sized Heterobiaryl Atropisomeric Rings and Atropopeptides by Catalytic Intramolecular SNAr

Angewandte Chemie, EarlyView.
Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani, Paritosh Dey, Nicholas H. Stillman, Daniel M. Andrade, Michal Šimek, Martin Dračínský, Daniel Bím, Paulo H. S. Paioti   +7 more
wiley   +1 more source

Carbon Insertion into Electron-Deficient (Aza)indoles via a Radical-Polar Crossover Strategy. [PDF]

J Am Chem Soc
Roth AD, Hyland EE, Cook AJ, Lynch-Colameta T, Christian AH, Levin MD.   +5 more
europepmc   +1 more source