Results 131 to 140 of about 41,236 (276)
Angewandte Chemie, EarlyView.A new class of “super‐strained” spiro heterocycles—spirocyclic 1‐azabicyclo[1.1.0]butanes—was synthesized via insertion of cyclobutane‐, oxetane‐, and azetidine‐containing sulfonium reagents into substituted azirines. The stability of this new class of compounds was studied.
Philipp Natho +9 more
wiley +2 more sources
Rational Design of π‐Conjugated Polymers for Enantioselective Recognition of Amino Acids
Advanced Electronic Materials, EarlyView.A family of conducting polymers is proposed for the enantioselective recognition of amino acids. The films are generated by electropolymerization of thiophene trimers containing chiral features, with the advantage that the polymerization can be induced at much lower overpotentials compared to classic thiophene monomers, thus avoiding parasitic ...
Gerardo Salinas +8 more
wiley +1 more source
Palladium‐Catalyzed Annulations of an Anti‐Bredt Olefin
Angewandte Chemie, EarlyView.We report metal‐catalyzed trappings of a [2.2.1]‐bridged bicyclic anti‐Bredt olefin (ABO). The methodology yields unusual heterocyclic products and is expected to prompt the further development of unconventional reactions, including metal‐catalyzed processes of ABOs and other strained olefins. ABSTRACT A famous class of alkene‐containing compounds that
Zach G. Walters +3 more
wiley +2 more sources
AgriFood: Journal of Agricultural Products for Food, EarlyView.Heavy metal pollution reduces soil health and threatens food safety by entering plants; however, the use of nanoparticles, biofertilizers, and organic fertilizers such as biochar offers a promising strategy for improvement and sustainable agriculture. ABSTRACT Heavy metal (HM) pollution, resulting from human activities such as mining and the excessive ...
Sina Siavash Moghaddam +4 more
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.The gut–brain axis is a bidirectional communication network between the intestines and brain, mediated by gut microbiota and exosomes, that regulates neuroinflammation, protein aggregation, and neuronal health processes central to neurodegenerative diseases.
Waheeb Sami Aggad +9 more
wiley +1 more source
Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles
Angewandte Chemie, EarlyView.Saturated nitrogen‐containing heterocycles are ubiquitous in bioactive molecules and are thus attractive synthetic targets. A readily accessible cyclometalated iridium(III) complex reduces 14 different aromatic aza heterocycles to (partially)saturated multi aza‐heterocycles enlarging accessible chemical space while displaying high tolerance toward ...
Arthur Despois, Nicolai Cramer
wiley +2 more sources
27: Some Natural and Unnatural Indoles (1990) [PDF]
, 2015 Liversidge Research Lecture delivered before the Royal Society of New South Wales, September 5th, 1990, at the University of New South Wales. Reproduced by permission of the Royal Society of New South Wales from J. Proc. Roy. N.S.W., 1990, 123, 1-13."New
Black, David St Clair
core
Generation of the Camptothecin Scaffold by a Flavin‐Catalyzed Photooxidative Skeletal Reorganization
Angewandte Chemie, EarlyView.The biosynthetic pathway of the anticancer drug precursor camptothecin involves an enigmatic skeletal reorganization from a 6/5/6 tetrahydro‐β‐carboline to a 6/6/5 pyrroloquinoline ring system. Here, we show that this transformation can be achieved by photooxidation with flavin cofactors, such as flavin mononucleotide (FMN) as catalysts.
Shenyu Liu +6 more
wiley +2 more sources
Mapping Proton‐Coupled Electron Transfer With Real Space Coordinates
Angewandte Chemie, EarlyView.We explore how proton‐coupled electron transfer (PCET) proceeds on a potential energy surface defined by two coordinates for proton and electron transfer that are obtained from quantum chemical calculations. The two‐dimensional maps for PCET show distinct characteristics for concerted proton–electron transfer and hydrogen atom transfer.
Adam Šrut +4 more
wiley +2 more sources
Transition Metal‐Free Heteroarene Insertion Into C─C Bonds of Benzocyclobutenones
Angewandte Chemie, EarlyView.A transition metal‐free insertion of five‐membered heteroarenes into the C─C bonds of benzocyclobutenones has been achieved under mild and operationally simple conditions. This method provides an efficient and modular approach to access fused partially saturated hetero‐polycyclic scaffolds that exist in many bioactive molecules.
Cole J. Wagner, Guangbin Dong
wiley +2 more sources