Results 151 to 160 of about 27,606 (220)

NaHMDS/B(C₆F₅)₃-promoted diastereoselective Friedel-Crafts alkylation of indoles/pyrroles with <i>N-tert</i>-butanesulfinylimines: towards the asymmetric synthesis of bisindole alkaloid Calcicamide B. [PDF]

RSC Adv
Zhang G, Chen X, Liu Y, Peng R, Xu M, Yan S, Xiao J, Liu Z, Min Q, Liao G, Wang X, Qin S.   +11 more
europepmc   +1 more source

Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases

iNew Medicine, EarlyView.
ABSTRACT Insulin resistance is the biological phenomenon in which the human body's normal response to the metabolic hormone insulin is compromised. Insulin is a regulator of most of the essential metabolic steps in the body that control energy homoeostasis, so dysregulation leads to multiple diverse human diseases including, most prominently, Type 2 ...
Peter J. Little, Stefan Offermanns, Haaglim Cho, Zhiping Liu, Pinglian Yang, Qiaozhu Su, Henry Wade, Wah Yang, Danielle Kamato, Neale Cohen, Alex Bobik, Iqra Ilyas, Suowen Xu   +12 more
wiley   +1 more source

Palladium-Catalyzed Heteroannulation of Bdan-Capped Alkynes: Rapid Access to Complex Indole Scaffolds. [PDF]

J Org Chem
Roberts DD, Halford-McGuff JM, Varga M, McKay AP, Watson AJB.   +4 more
europepmc   +1 more source

Gut microbiome‐derived metabolites show promise in cancer research and therapy

Interdisciplinary Medicine, EarlyView.
The metabolites produced by the gut microbiome, which are subject to regulation by multiple factors, play a pivotal role in the progression of various types of cancer. These metabolites not only function as potential biomarkers for the early detection and monitoring of tumor development, but also actively participate in cancer therapeutic processes ...
Kangjie Yang, Yifan Wang, Daolin Tang, Peilong Li, Lutao Du   +4 more
wiley   +1 more source

Microbiota-Derived Regulation of AhR and VDR Signaling in Intestinal Inflammation: Protective Roles of Prebiotics, Probiotics, and Postbiotics. [PDF]

Int J Mol Sci
Huang FC.
europepmc   +1 more source

Experimental Assessment of the Effects of Substrate Choice on the Duration of Chemical Signals in Fecal Scent‐Marks of Free‐Ranging Iberian Wolves

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, EarlyView.
ABSTRACT Chemical communication, typically based on feces, urine, and glandular secretions, often deposited as substrate scent marks, plays a key role in social organization and communication among many mammals, especially carnivores. This study assesses experimentally whether the type of substrate chosen for fecal deposition and the temperature ...
Elisa Espartosa, Jose Martin, Isabel Barja   +2 more
wiley   +1 more source

Iridium-Catalyzed Direct and Site-Selective C-H Heteroarylation, Alkenylation, and Alkylation of Indoles. [PDF]

J Org Chem
Cao T, Hu W, Hao L, Guo L, Wu L, Xu L, Gao Z, Li J, Tian F, Wu X.   +9 more
europepmc   +1 more source

Indole‐Based π‐Extended Monophosphine Ligands for Enhanced Palladium‐Catalyzed Sonogashira Coupling

Journal of Heterocyclic Chemistry, EarlyView.
A general palladium‐catalyzed Sonogashira cross‐coupling of (hetero)aryl chlorides with aliphatic, (hetero)aryl alkynes is described using Pd(dba)₂/PCy2‐Napdole‐phos catalyst system. The reaction protocol exhibits broad substrate scope and the catalyst loading can be down to 0.2 mol% Pd.
Yu Kiu Lau, Chun Pong Hui, Cheuk Long Li, Ho Chung Chang, Man Ho Tse, Ho Kwan Lou, Iat In Chan, Raymond Wai‐Yin Sun, Pui Ying Choy, Fuk Yee Kwong   +9 more
wiley   +1 more source

Site-Selective Benzylic Dehydrogenation of Alkylindoles. [PDF]

JACS Au
Zhang X, Kang X, Ren J, Wang J, Liu XJ.
europepmc   +1 more source

Carbon Dots as Nano-Photocatalysts: A Green Tool for Indole and Heteroarenes Alkylation. [PDF]

Chemistry
Sargueil J, Santoni M, Cichella S, Sabato AD, Moldoveanu VG, Sturabotti E, Simonis B, Giustini M, Migneco LM, Leonelli F, Vetica F.   +10 more
europepmc   +1 more source