Results 91 to 100 of about 90,075 (209)
Enhanced mitochondrial activity reshapes a gut microbiota profile that delays NASH progression
Hepatology, EarlyView., 2022 Improved mitochondrial activity, due to the lack of methylation‐controlled J protein (MCJ), creates a specific microbiota signature that when transferred through cecal microbiota transplantation delays NASH progression by restoring the gut‐liver axis and enhancing hepatic fatty acid oxidation.
María Juárez‐Fernández +18 more
wiley +1 more source
AgriFood: Journal of Agricultural Products for Food, EarlyView.Natural Pharmaco‐remedial impacts of Allium sativum on Systemic health. ABSTRACT Arising from the emergence of diverse difficult‐to‐treat health cases, alterative‐therapeutic strategies have become a potential way forward for management/control. In traditional Chinese medicine (TCM), various plant materials have been sourced as alterative‐therapeutic ...
Patience O. Adomi +3 more
wiley +1 more source
, 1984 The Nenitszescu reaction has been investigated as a means of preparing several indoles, benz[g]-indoles and 1,2-annulated indoles (3),(9),(13),(17) and (18) and a number of their derivatives.Reactions between benzoquinone and enaminones to form Michael ...
RW Parr, JA Reiss
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International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Patients with chronic rhinosinusitis with nasal polyps (CRSwNP) exhibit heterogeneous responses to oral glucocorticoids (GCs), but the biological basis of this variability remains unclear. Objective To identify gut microbiome‒plasma metabolomic signatures associated with GC responsiveness in CRSwNP patients and to compare their ...
Ying‐Ying Zhang +7 more
wiley +1 more source
Electrophilic Substitutions of Indoles and Pyrroles: [PDF]
, 2007 The kinetics of the electrophilic substitutions of indoles and pyrroles have been investigated and new sythetic applications (i.e. electrophilic allylations and benzylations of indoles and regio- and stereoselective ring opening reactions of epoxides ...
Westermaier, Martin
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, 2013 Cu(OTf)2-Catalyzed Asymmetric Friedel-Crafts Alkylation Reaction of Indoles with Arylidene Malonates Using Bis(sulfonamide)-Diamine ...
吴凡, 王东平, 万伯顺, 吴静
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Synthetic applications of 3-(cyanoacetyl)indoles and related compounds
, 2005 Various synthetic applications of 3-(cyanoacetyl)indoles, as well as syntheses of some related indoles, have been investigated. Di-Et 2-(1H-indol-3-yl)-2-oxoethylphosphonate and a Me deriv. thereof have been prepd. in one step from indole.
Janosik, Tomasz, +5 more
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Friedel–Crafts hydroxyalkylation of indoles mediated by trimethylsilyl trifluoromethanesulfonate [PDF]
, 2015 Indoles and N-alkylindoles undergo Friedel–Crafts addition to aldehydes in the presence of trimethylsilyl trifluoromethanesulfonate and a trialkylamine to produce 3-(1- silyloxyalkyl)indoles.
Downey, C. Wade +2 more
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Angewandte Chemie, EarlyView.Catalytic, intramolecular N‐heterocycle arylation by nucleophilic aromatic substitution (SNAr) is now available for synthesis of highly strained macrocycles and medium‐sized heterobiaryl atropisomeric rings, including atropopeptides. Key to the approach is the ability to generate a strong base catalytically, taking advantage of base‐embedding ...
Alireza Abbasi Kejani +7 more
wiley +1 more source
27: Some Natural and Unnatural Indoles (1990)
, 2015 Liversidge Research Lecture delivered before the Royal Society of New South Wales, September 5th, 1990, at the University of New South Wales. Reproduced by permission of the Royal Society of New South Wales from J. Proc. Roy. N.S.W., 1990, 123, 1-13."New
Black, David St Clair
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