Results 161 to 170 of about 887 (215)

The Structure of Carboxyl Methyltransferase Provides Insights Into the Substrate Specificity and Divergent Evolution of Iridoid

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Iridoids constitute a prominent class of plant‐specialised metabolites, with carbocyclic iridoids (e.g., geniposide) and secoiridoids (e.g., loganin) diverging early in their biosynthetic pathways. This divergence is marked by substrate‐specific carboxyl methyltransferases—GjGAMT and CrLAMT—that catalyse the decisive methylation step in ...
Li Li   +7 more
wiley   +1 more source

Deciphering Cold Stress Resilience: Multiomics Insights in Contrasting Wheat Genotypes From the Western Himalayas

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Cold stress threatens wheat productivity, particularly in regions with extreme climatic conditions. To elucidate the molecular mechanisms underlying wheat's response to cold stress, we performed a multiomics analysis integrating lipidomics, transcriptomics, proteomics and metabolomics.
Sofora Jan   +15 more
wiley   +1 more source

Total synthesis of monoterpenoid indole alkaloid (–)-arbophyllidine

Organic Chemistry Frontiers, 2022
The first asymmetric total synthesis of (–)-arbophyllidine, an unusual pentacyclic monoterpenoid indole alkaloid, has been achieved.
Hongbin Zhai   +5 more
openaire   +1 more source

Total Synthesis of Indole Alkaloid (±)-Subincanadine E

Organic Letters, 2014
The first total synthesis of indole alkaloid (±)-subincanadine E has been accomplished. Ni(COD)2-mediated intramolecular Michael addition and zinc-mediated fragmentation reaction served as two key transformations.
Jingjing, Tian   +5 more
openaire   +2 more sources

Total Synthesis of Indole Alkaloid Alsmaphorazine D

Angewandte Chemie International Edition, 2014
AbstractA concise total synthesis of rac‐alsmaphorazine D has been described for the first time. The efficient synthetic strategy features four key transformations: 1) a catalytic intramolecular oxidative cyclization for the δ‐lactamindole backbone; 2) an oxidative cyclic aminal formation for the hexahydropyrrolo[2,3‐b]pyrrole framework; 3) a ...
Chenlong, Zhu   +4 more
openaire   +2 more sources

Total synthesis of indole alkaloid pendolmycin

Tetrahedron, 1990
Abstract The teleocidin class of an indole alkaloid, pendolmycin (1) was synthesized from 1-(4-methylphenylsulfonyl)pyrrole in thirteen steps by way of the indole derivative (16), the amino- diester compound (6), and the ethyl carboxylate (5).
Kazuaki Okabe   +2 more
openaire   +1 more source

Total Syntheses of (−)‐Strictosidine and Related Indole Alkaloid Glycosides

Angewandte Chemie, 2020
AbstractA collective synthesis of glycosylated monoterpenoid indole alkaloids is reported. A highly diastereoselective Pictet–Spengler reaction with α‐cyanotryptamine and secologanin tetraacetate as substrates, followed by a reductive decyanation reaction, was developed for the synthesis of (−)‐strictosidine, which is an important intermediate in ...
Jukiya Sakamoto   +4 more
openaire   +2 more sources

Asymmetric Total Syntheses of Kopsia Indole Alkaloids

Angewandte Chemie International Edition, 2017
AbstractThe asymmetric total syntheses of a group of structurally complex Kopsia alkaloids, (−)‐kopsine, (−)‐isokopsine, (+)‐methyl chanofruticosinate, (−)‐fruticosine, and (−)‐kopsanone, has been achieved. The key strategies for the construction of the molecular complexity in the targets included an asymmetric Tsuji–Trost rearrangement to set the ...
Lingying, Leng   +7 more
openaire   +2 more sources

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