Results 181 to 190 of about 90,075 (209)
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Total Synthesis of the Indole Alkaloid (±)‐ and (+)‐Methyl N‐Decarbomethoxychanofruticosinate
Angewandte Chemie International Edition, 2013All caged up: The first total synthesis of N-decarbomethoxychanofruticosinate is achieved by using a SmI2 -mediated intramolecular Reformatsky-like reaction to create the seven-membered ring, and an intramolecular oxidative coupling to install the caged and strained ring system.
Yi, Wei, Duo, Zhao, Dawei, Ma
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Total Syntheses of the Monoterpenoid Indole Alkaloids (±)‐Alstoscholarisine B and C
Angewandte Chemie, 2017AbstractTotal syntheses of the monoterpenoid indole alkaloids (±)‐alstoscholarisine B and C were accomplished starting from a readily available indole‐2‐acetic ester and an α,β‐unsaturated N‐sulfonyllactam.
Jeremy D. Mason, Steven M. Weinreb
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Metamorphosis of cycloalkenes for the divergent total synthesis of polycyclic indole alkaloids
Chemical Society Reviews, 2018This review summarizes the divergent synthesis of monoterpene indole alkaloids using cycloalkene as the turning point of structural diversity.
Zhengren Xu, Qian Wang, Jieping Zhu
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Hexacyclic indole alkaloids. A highly convergent total synthesis of cuanzine
The Journal of Organic Chemistry, 1991A novel route to the hexacyclic indole alkaloid cuanzine 1 has been developed. Key synthetic steps include the cyclocondensation of the imine 8 with the dihydrofuran 10 followed by homogeneous-catalyzed hydrogenation, wherein to COOMe group at C(20) serves as a diastereocontrol element in establishing the C(15) stereogenicity.
G. PALMISANO +4 more
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Direct approaches to annulated indoles. A formal total synthesis of 0231B
Tetrahedron, 2005AbstractFor Abstract see ChemInform Abstract in Full Text.
George A. Kraus, Tao Wu
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Organic Letters, 2017
A conceptually new synthetic approach that provides general access to the aspidosperma alkaloids (+)-aspidospermidine and (-)-tabersonine was developed. This method is based on the regioselective indolization of an ene-hydrazide, which was obtained via a base-catalyzed intramolecular aza-Michael reaction, in situ trapping of the resulting enolate, and ...
Joo-Young Kim +3 more
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A conceptually new synthetic approach that provides general access to the aspidosperma alkaloids (+)-aspidospermidine and (-)-tabersonine was developed. This method is based on the regioselective indolization of an ene-hydrazide, which was obtained via a base-catalyzed intramolecular aza-Michael reaction, in situ trapping of the resulting enolate, and ...
Joo-Young Kim +3 more
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Organic Letters, 2001
[structure: see text] The total synthesis of the indole alkaloid trinervine 1 was accomplished in enantiospecific fashion in an overall yield of 20% (from the tetracyclic ketone 8) in 10 reaction vessels (12.5% from tryptophan methyl ester). The synthesis of the N(a)-H substituted macroline equivalent 2 was also completed in high yield via the same ...
X, Liu, J M, Cook
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[structure: see text] The total synthesis of the indole alkaloid trinervine 1 was accomplished in enantiospecific fashion in an overall yield of 20% (from the tetracyclic ketone 8) in 10 reaction vessels (12.5% from tryptophan methyl ester). The synthesis of the N(a)-H substituted macroline equivalent 2 was also completed in high yield via the same ...
X, Liu, J M, Cook
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Divergent Enantioselective Total Synthesis of Aspidosperma Indole Alkaloids
The Journal of Organic ChemistryWe present a collective asymmetric synthesis of 11 aspidosperma indole alkaloids, (-)-aspidospermidine (1), (-)-N-methylaspidospermidine (2), (+)-O-demethylaspidospermine (3), (+)-aspidospermine (4), (-)-eburenine (5), (+)-quebrachamine (6), (-)-vincadifformine (7), (-)-limaspermidine (8), (+)-12-demethoxy-N-acetylcylindrocarine (9), (-)-N ...
Dong-Xing Tan, Fu-She Han
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Total Synthesis of the Tremorgenic Indole Diterpene Paspalinine
Angewandte Chemie International Edition, 2012Masaru, Enomoto +2 more
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