Results 11 to 20 of about 90,075 (209)
Total Synthesis of the Bridged Indole Alkaloid Apparicine [PDF]
The Journal of Organic Chemistry, 2009 An indole-templated ring-closing metathesis or a 2-indolylacyl radical cyclization constitute the central steps of two alternative approaches developed to assemble the tricyclic ABC substructure of the indole alkaloid apparicine. From this key intermediate, an intramolecular vinyl halide Heck reaction accomplished the closure of the strained 1 ...
Bennasar Fèlix, M. Lluïsa +5 more
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Recent advances in the total syntheses of indole diterpenoids [PDF]
Bioscience, Biotechnology, and Biochemistry, 2021 Abstract Indole diterpenoids constitute a large family of natural products that are characterized by a hybrid molecular architecture consisting of an indole nucleus and diterpenoid moiety. Their pharmacologically and agriculturally important biological properties as well as intriguing molecular architectures have attracted much attention
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Undirected, Pd-catalysed deuteration of indoles with programmable regioselectivity [PDF]
, 2022 Methods for selective deuterium-incorporation into drug-like molecules have become extremely valuable due to the commercial and biological importance of deuterated compounds.
Rachael, McNulty +7 more
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, 2022 Establishing three-dimensional chemicals by using the C2–C3 π bond of indoles has always been a research hotspot in organic synthesis; however, employing the oxidative C2–C3 π bond of indoles to generate imine which would lead to the N1–C2 π bond ...
Kui Du (3488084) +6 more
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Oxidative rearrangement of indoles to oxindoles [PDF]
, 2012 An unexpected oxidative rearrangement was observed when indoles substituted with 2-hydroxymalonates were subjected to typical iodination conditions.
Rodriguez, Arantxa +2 more
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Efficient copper-catalyzed synthesis of C3-alkylated indoles from indoles and alcohols
, 2021 A highly efficient copper(II) catalyst system for alkylation of indoles with alcohols via hydrogen borrowing method has been developed to afford C3-alkylated indoles in good to excellent yields. Cu(OAc)2 in the combination with dppm ligand has been found
Van Phuc, Ban +20 more
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Total Synthesis of Indole Alkaloids [PDF]
Synfacts, 2016 Significance: Indole alkaloids represent challenging synthetic targets due to their highly congested architecture and rich chemical functionality. Li and co-workers report the first enantioselective total synthesis of (–)-aspidodasycarpine and (–)-lonicerine.
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Determination of Free and Total Indole-3-acetic Acid and of the Indole Index
Clinical Chemistry, 1964 Abstract A new method is described for measurement of the urinary excretion of free and total indole-3-acetic acid and for obtaining the chromogenic value of the total indoles. The color reaction employed is Fischl's (1) tryptophan reaction. Hydrolysis and extractions were done by Weissbach's (2) procedure.
J, FISCHL, S, RABIAH
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Total Synthesis of the Unusual Monoterpenoid Indole Alkaloid (±)‐Alstilobanine A [PDF]
Angewandte Chemie International Edition, 2012 The monoterpene indole alkaloids, which are usually comprised of a tryptamine moiety appended to a single C9- or C10-terpenoid unit, constitute one of the largest known classes of natural products.[1] In 2004, Kam and Choo isolated a new type of monoterpenoid indole alkaloid, angustilodine (1), which contains a unique rearranged skeleton, from the ...
Yiqing, Feng +2 more
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Umpolung of Indoles: Triflic Acid-Mediated C3-Regioselective Hydroarylation of N-H Indoles [PDF]
, 2022 The direct dearomative addition of arenes to the C3-position of unprotected indoles is reported under operationally simple condi-tions, using triflic acid at room temperature.
Vincent, Gandon +4 more
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