Results 1 to 10 of about 887 (215)
Total Synthesis of the Bridged Indole Alkaloid Apparicine [PDF]
The Journal of Organic Chemistry, 2009 An indole-templated ring-closing metathesis or a 2-indolylacyl radical cyclization constitute the central steps of two alternative approaches developed to assemble the tricyclic ABC substructure of the indole alkaloid apparicine. From this key intermediate, an intramolecular vinyl halide Heck reaction accomplished the closure of the strained 1 ...
Bennasar Fèlix, M. Lluïsa +5 more
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Total synthesis of the indole alkaloid (±)-tacamine
Tetrahedron Letters, 1994 Abstract The mixture of pentacyclic intermediates ( 4 ) was successfully converted into the pharmacologically interesting indole alkaloid (±)-tacamine ( 1 ). In a similar manner, the two unnatural isomers of 1 , (±)-14-epitacamine ( 9 ) and (±)-14-epi-16-epitacamine ( 10 ), were obtained from intermediate 7 .
Mauri Lounasmaa +2 more
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Total Synthesis of Indole Alkaloids [PDF]
Synfacts, 2016 Significance: Indole alkaloids represent challenging synthetic targets due to their highly congested architecture and rich chemical functionality. Li and co-workers report the first enantioselective total synthesis of (–)-aspidodasycarpine and (–)-lonicerine.
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Total Synthesis of the Chlorinated Pentacyclic Indole Alkaloid (+)-Ambiguine G [PDF]
Journal of the American Chemical Society, 2021 Reported herein is the total synthesis of (+)-ambiguine G, the first member of the chlorinated pentacyclic ambiguines to yield to chemical synthesis. The synthesis is accomplished through a convergent strategy that proceeds in 10 steps from (S)-carvone oxide.
Lingbowei Hu, Viresh H. Rawal
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Revista Colombiana de Biotecnología, 2014 Título en español: Efecto de rizobacterias promotoras de crecimiento vegetal solubilizadoras de fosfato en Lactuca sativa cultivar White Boston Título en ingles: Effect of plant growth promoting rhizobacteria phosate solubilizing Lactuca sativa ...
Diana Beatriz Sanchez López +3 more
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Recent advances in the total syntheses of indole diterpenoids [PDF]
Bioscience, Biotechnology, and Biochemistry, 2021 Abstract Indole diterpenoids constitute a large family of natural products that are characterized by a hybrid molecular architecture consisting of an indole nucleus and diterpenoid moiety. Their pharmacologically and agriculturally important biological properties as well as intriguing molecular architectures have attracted much attention
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Asymmetric Total Synthesis of the Indole Diterpene Alkaloid Paspaline [PDF]
The Journal of Organic Chemistry, 2015 An enantioselective synthesis of the indole diterpenoid natural product paspaline is disclosed. Critical to this approach was the implementation of stereoselective desymmetrization reactions to assemble key stereocenters of the molecule. The design and execution of these tactics are described in detail, and a thorough analysis of observed outcomes is ...
Robert J, Sharpe, Jeffrey S, Johnson
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Total synthesis of the tetracyclic indole alkaloid ht-13-A [PDF]
Tetrahedron Letters, 2015 An expedient synthesis corroborating the proposed structure of the tetracyclic indole alkaloid ht-13-B is presented. Key synthetic steps include acyliminium ion allylation, a Mitsunobu reaction, a palladium-catalyzed Stille-Kelly cross coupling reaction, and a carbon monoxide-mediated palladium-catalyzed reductive N-heterocyclization.
Yilin, Zhang +4 more
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Revista Colombiana de Biotecnología, 2012 Título en ingles: Evaluation of microorganisms with potential for plant growth promotion and biological control of Spongospora subterranea Resumen: La sarna polvosa de la papa es causada por el patógeno Spongospora subterranea, que disminuye la ...
Juliana Soler Arango +2 more
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Total Synthesis of the Unusual Monoterpenoid Indole Alkaloid (±)‐Alstilobanine A [PDF]
Angewandte Chemie International Edition, 2012 The monoterpene indole alkaloids, which are usually comprised of a tryptamine moiety appended to a single C9- or C10-terpenoid unit, constitute one of the largest known classes of natural products.[1] In 2004, Kam and Choo isolated a new type of monoterpenoid indole alkaloid, angustilodine (1), which contains a unique rearranged skeleton, from the ...
Yiqing, Feng +2 more
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