Results 141 to 150 of about 6,816 (174)

Indoxyl sulfate in atherosclerosis

Toxicology Letters, 2023
Atherosclerosis (AS), a chronic vascular inflammatory disease, has become a main focus of attention worldwide for its chronic progressing disease course and serious complications in the later period. Nevertheless, explanations for the exact molecular mechanisms of AS initiation and development remain to be an unsolved problem.
Cong, Lu, Li, Wu, Mu-Yao, Tang, Yi-Fan, Liu, Lei, Liu, Xi-Ya, Liu, Chun, Zhang, Liang, Huang   +7 more
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Indoxyl Sulfate Induces Nephrovascular Senescence

Journal of Renal Nutrition, 2012
Indoxyl sulfate is markedly accumulated in the serum of chronic kidney disease (CKD) patients. The oral sorbent AST-120 reduces serum levels of indoxyl sulfate in CKD patients by adsorbing indole, a precursor of indoxyl sulfate, in the intestine. Indoxyl sulfate is taken up by proximal tubular cells through organic anion transporters (OAT1, OAT3), and ...
Toshimitsu, Niwa, Hidehisa, Shimizu
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Growth-Promoting Activity of Potassium Indoxyl Sulfate and Indoxyl Acetate

Botanical Gazette, 1954
1. In this paper exploratory experiments have been described in which some oxidized indole derivatives have stimulated slightly the growth of corn coleoptile sections. 2. When potassium indoxyl sulfate and indoxyl acetate were supplied, light appeared to modify greatly the growth response. 3. Whether considered as degradation products in the metabolism
Richard C. French, Harry Beevers
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Indoxyl Sulfate and Arteriosclerosis

2020
The uremic toxin indoxyl sulfate, metabolized from dietary tryptophan, accumulates in the serum of patients with decreased renal function. A higher level of serum indoxyl sulfate is reported to be an independent risk factor for cardiovascular events and death in patients with chronic kidney disease.
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Effect of uremic toxin-indoxyl sulfate on the skeletal system

Clinica Chimica Acta, 2018
Chronic kidney disease-mineral bone disorders (CKD-MBD) exhibit abnormalities in the circulating mineral levels, vitamin D metabolism, and parathyroid function that contribute to the formation of a bone lesion. The uremic toxin, indoxyl sulfate (IS), accumulates in the blood in cases of renal failure and leads to bone loss. The bone and renal responses
Wen-Chih, Liu, Chia-Chao, Wu, Paik-Seong, Lim, Shiaw-Wen, Chien, Yi-Chou, Hou, Cai-Mei, Zheng, Jia-Fwu, Shyu, Yuh-Feng, Lin, Kuo-Cheng, Lu   +8 more
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Indoxyl Sulfate Is a Nephro-Vascular Toxin

Journal of Renal Nutrition, 2010
Indoxyl sulfate is markedly accumulated in the serum of patients with chronic kidney disease (CKD). The oral sorbent AST-120 reduces the serum levels of indoxyl sulfate in CKD patients by adsorbing indole, a precursor of indoxyl sulfate, in the intestine, and thereby stimulating its excretion in feces. AST-120 is used for the treatment of patients with
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Indoxyl Sulfate and Atherosclerotic Risk Factors in Hemodialysis Patients

American Journal of Nephrology, 2007
<i>Background:</i> Indoxyl sulfate is a uremic toxin that accelerates the progression of chronic kidney disease (CKD). Serum levels of indoxyl sulfate are increased in dialysis patients. It was reported that indoxyl sulfate plays a role in endothelial dysfunction in uremic patients, and stimulates proliferation of rat vascular smooth muscle
Kentaro, Taki, Yoshinari, Tsuruta, Toshimitsu, Niwa   +2 more
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Performance evaluation of an Indoxyl Sulfate Assay Kit “NIPRO”

Clinical Chemistry and Laboratory Medicine (CCLM), 2019
Abstract Background The relationship between renal disease and cardiovascular disease (CVD) is currently known as cardiorenal syndrome. Indoxyl sulfate (IS) is one of the uremic toxins that accelerates the progression of cardiorenal syndrome.
Yuki, Fushimi, Junko, Tatebe, Yuko, Okuda, Toshiaki, Ishii, Shinji, Ujiie, Toshisuke, Morita   +5 more
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The influence of indoxyl sulfate and ammonium on the autofluorescence of human urine

Talanta, 2010
Despite biological variability the spectral characteristics of undiluted human urine show relatively low autofluorescence at short UV (250-300nm) excitation. However with dilution the fluorescence intensity remarkably increases. This paper examines the mechanisms behind this effect, by using excitation-emission matrices.
Sandeep Menon, Perinchery, Unnikrishnan, Kuzhiumparambil, Subramanyam, Vemulpad, Ewa M, Goldys   +3 more
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Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-β-d-glucoside (indican) in rats

Toxicon, 2008
Indican (Indoxyl-beta-D-glucoside) is present in many Chinese herbs such as Isatis indigotica, Clerodendrum crytophyllum, Glehnia littoralis, Polygonum tinctorium and P. perfoliatum. This study aims to investigate whether indoxyl sulfate, a uremic toxin, would be biotransformed from indican in rats.
Yu-Chi, Hou, Shang-Yuan, Tsai, Shu-Ling, Chan, Shih-Ying, Yang, Pei-Dawn Lee, Chao   +4 more
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