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Indoxyl sulfate, a uremic toxin, is biotransformed from indoxyl-β-d-glucoside (indican) in rats

Toxicon, 2008
Indican (Indoxyl-beta-D-glucoside) is present in many Chinese herbs such as Isatis indigotica, Clerodendrum crytophyllum, Glehnia littoralis, Polygonum tinctorium and P. perfoliatum. This study aims to investigate whether indoxyl sulfate, a uremic toxin, would be biotransformed from indican in rats.
Yu-Chi, Hou   +4 more
openaire   +2 more sources

Indoxyl-beta-D-glucuronide and 3-indoxyl sulfate in plasma of hemodialysis patients.

Clinical nephrology, 1997
The content of indoxyl-beta-D-glucuronide, which has been found in patients' plasma as a new indicator of renal failure, logarithmically correlated with that of 3-indoxyl sulfate (indican) in the plasma of hemodialysis patients, showing another weak correlation with beta(2)-microglobulin content.
S, Agatsuma, H, Sekino, H, Watanabe
openaire   +1 more source

Uremic Toxin Indoxyl Sulfate Promotes Macrophage-Associated Low-Grade Inflammation and Epithelial Cell Senescence

International Journal of Molecular Sciences, 2023
Maciej Lech   +2 more
exaly  

Major Role of Organic Anion Transporter 3 in the Transport of Indoxyl Sulfate in the Kidney

Kidney International, 2002
Tetsuya Terasaki   +2 more
exaly  

Interactions of Human Organic Anion as Well as Cation Transporters With Indoxyl Sulfate

European Journal of Pharmacology, 2003
Atsushi Enomoto   +2 more
exaly  

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