Results 111 to 120 of about 394,249 (378)

DIRECTED RE-PROGRAMMING OF SOMATIC CELLS: ADVANTAGES AND LIMITATIONS OF INDUCED PLURIPOTENT STEM CELLS (REVIEW)

open access: yesСибирский научный медицинский журнал, 2019
Stem cells are divided into embryonic and adult stem cells. The relevance of the use of stem cells in clinical practice has received new evidence in recent years however, the methods of obtaining stem cells for medical purposes cause ethical rejection ...
A. V. Korel, S. B. Kuznetsov
doaj   +1 more source

Bioengineering of functional human induced pluripotent stem cell-derived intestinal grafts

open access: yesNature Communications, 2017
Patients with short bowel syndrome lack sufficient functional intestine to sustain themselves with enteral intake alone. Transplantable vascularized bioengineered intestine could restore nutrient absorption.
K. Kitano   +11 more
semanticscholar   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

open access: yesAdvanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana   +2 more
wiley   +1 more source

A Visible Light‐Responsive Hydrogel to Study the Effect of Dynamic Tissue Stiffness on Cellular Mechanosensing

open access: yesAdvanced Functional Materials, EarlyView.
A visible light‐responsive polyacrylamide‐azobenzene hydrogel enables safe, reversible stiffness control for studying cell mechanobiology without harmful UV exposure. This approach reveals stem cells respond rapidly to mechanical changes, showing altered shape and protein distribution within one hour.
Aafreen Ansari   +11 more
wiley   +1 more source

Establishment of pluripotent cell lines from vertebrate species - Present status and future prospects [PDF]

open access: yes, 1999
Pluripotent embryonic stem (ES) cells are undifferentiated cell lines derived from early embryos and are capable of unlimited undifferentiated proliferation in vitro.
Prelle, Katja   +4 more
core   +1 more source

Generation of a human induced pluripotent stem cell line KUMi006 from a patient with multiple myeloma

open access: yesStem Cell Research, 2022
In this study, we report the generation of a novel human induced pluripotent stem cell (hiPSC) line from bone marrow mononuclear cells of a patient with multiple myeloma, using an integrative Sendai virus vector. This pluripotent cell line has been shown
Ji-Hyeon Hong   +5 more
doaj  

High purity human-induced pluripotent stem cell-derived cardiomyocytes: electrophysiological properties of action potentials and ionic currents.

open access: yesAmerican Journal of Physiology. Heart and Circulatory Physiology, 2011
Human-induced pluripotent stem cells (hiPSCs) can differentiate into functional cardiomyocytes; however, the electrophysiological properties of hiPSC-derived cardiomyocytes have yet to be fully characterized.
Junyi Ma   +8 more
semanticscholar   +1 more source

Perfusable Brain Microvascular Network‐On‐Chip Model to Study Flavivirus NS1‐Induced Endothelial Dysfunction

open access: yesAdvanced Functional Materials, EarlyView.
This study presents a microfluidic brain microvascular network‐on‐chip (BMVasChip) to investigate endothelial barrier dysfunction caused by flavivirus non‐structural protein 1 (NS1), including virus‐ and time‐dependent vascular damage, leakiness, and dysfunction.
Monika Rajput   +5 more
wiley   +1 more source

Co-cultures with stem cell-derived human sensory neurons reveal regulators of peripheral myelination [PDF]

open access: yes, 2017
Effective bidirectional signalling between axons and Schwann cells is essential for both the development and maintenance of peripheral nerve function. We have established conditions by which human induced pluripotent stem cell-derived sensory neurons can
Bennett, David L.H.   +5 more
core   +2 more sources

Modeling human trophoblast, the placental epithelium at the maternal fetal interface. [PDF]

open access: yes, 2020
Appropriate human trophoblast lineage specification and differentiation is crucial for the establishment of normal placentation and maintenance of pregnancy. However, due to the lack of proper modeling systems, the molecular mechanisms of these processes
Bui, Tony   +3 more
core   +1 more source

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